Search Hotels Near St. Mary's Medical Center, San Francisco

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30 Dec - 31 Dec
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Our top choices for St. Mary's Medical Center hotels

Exterior
Chapter San Francisco

Chapter San Francisco

Chapter San Francisco
2.0 star property
3.1 km from St. Mary's Medical Center
9.2 out of 10, Wonderful, (380)
"Wonderful place to stay and relax. Professional staff and services."
United States
Syed
Chapter San Francisco
Interior entrance
Cow Hollow Inn & Suites

Cow Hollow Inn & Suites

Cow Hollow Inn & Suites
3.5 star property
Cow Hollow, 3.2 km from St. Mary's Medical Center
9.0 out of 10, Wonderful, (1466)
"Perfect for our 1 night stay in SF, walkable and convenient taxi rides to all areas. We would definitely stay again!"
United States
Ashlee
Cow Hollow Inn & Suites
Terrace/patio
Signature Inn San Francisco Marina District

Signature Inn San Francisco Marina District

Signature Inn San Francisco Marina District
2.0 star property
Marina District, 3 km from St. Mary's Medical Center
8.6 out of 10, Excellent, (352)
"Comfortable!"
United States
Franchesca
The price is ฿2,817
฿3,276 total
includes taxes & fees
4 Jan - 5 Jan 2026
Signature Inn San Francisco Marina District
Lobby
La Luna Inn, an Ascend Collection Hotel

La Luna Inn, an Ascend Collection Hotel

La Luna Inn, an Ascend Collection Hotel
2.5 star property
Cow Hollow, 2.9 km from St. Mary's Medical Center
8.2 out of 10, Very good, (365)
"Well located, Safe, Clean !!"
Canada
mohamed
The price is ฿2,936
฿3,421 total
includes taxes & fees
27 Jan - 28 Jan 2026
La Luna Inn, an Ascend Collection Hotel
Property entrance
Casa Loma Hotel

Casa Loma Hotel

Casa Loma Hotel
2.0 star property
Western Addition, 2 km from St. Mary's Medical Center
7.8 out of 10, Good, (1001)
"clean room, great location, easy check-in, redone bathroom, clean beds"
United States
Daniel
The price is ฿2,529
฿2,941 total
includes taxes & fees
25 Jan - 26 Jan 2026
Casa Loma Hotel
Shared kitchen
Hayes Valley Inn

Hayes Valley Inn

Hayes Valley Inn
2.0 star property
2.7 km from St. Mary's Medical Center
7.8 out of 10, Good, (318)
"Basic accommodation but clean and in a good area"
United Kingdom
Daniel
The price is ฿2,405
฿2,798 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hayes Valley Inn
Room, 1 Queen Bed, Non Smoking | In-room safe, desk, free WiFi, bed sheets
Inn at Golden Gate

Inn at Golden Gate

Inn at Golden Gate
2.0 star property
Marina District, 2.8 km from St. Mary's Medical Center
7.6 out of 10, Good, (1003)
"Good room"
United States
Diego
The price is ฿2,473
฿2,940 total
includes taxes & fees
5 Jan - 6 Jan 2026
Inn at Golden Gate
Standard Room, 1 Double Bed, Shared Bathroom | 1 bedroom, desk, laptop workspace, iron/ironing board
Perramont Hotel

Perramont Hotel

Perramont Hotel
2.0 star property
2.2 km from St. Mary's Medical Center
7.2 out of 10, Good, (109)
"Excellent bargain, clean rooms, and the owners let me store my baggage. "
United States
Joshua
The price is ฿1,955
฿2,274 total
includes taxes & fees
12 Jan - 13 Jan 2026
Perramont Hotel
Reception
Twin Peaks Hotel

Twin Peaks Hotel

Twin Peaks Hotel
2.0 star property
2.2 km from St. Mary's Medical Center
7.2 out of 10, Good, (145)
"Good room, clean, staff was great, hotel very secure. Will stay there again. "
United States
Joel
The price is ฿1,898
฿2,333 total
includes taxes & fees
30 Jan - 31 Jan 2026
Twin Peaks Hotel
Room | Free WiFi, bed sheets
Union Hotel

Union Hotel

Union Hotel
2.0 star property
3.2 km from St. Mary's Medical Center
7.0 out of 10, Good, (291)
"Great for the price point. Friendly staff and quiet hotel."
United States
Michael
The price is ฿1,709
฿1,991 total
includes taxes & fees
4 Jan - 5 Jan 2026
Union Hotel
Family Room Suite w/ Sofa Bed | Living area | TV
Surf Motel

Surf Motel

Surf Motel
2.0 star property
Cow Hollow, 3.1 km from St. Mary's Medical Center
7.0 out of 10, Good, (1000)
"Clean room"
United States
Aaron
The price is ฿1,846
฿2,150 total
includes taxes & fees
5 Jan - 6 Jan 2026
Surf Motel
Exterior
Hotel Sunrise

Hotel Sunrise

Hotel Sunrise
2.0 star property
3 km from St. Mary's Medical Center
6.8 out of 10, (638)
"Great place to stay in the heart of the Mission District. Spartan accomodations but excellent. Location is amazing. Dining options are limitless and it is so close to public transportation. "
United States
Brock
The price is ฿2,297
฿2,671 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Sunrise
View from property
Alpha Inn & Suites

Alpha Inn & Suites

Alpha Inn & Suites
2.0 star property
Cow Hollow, 2.9 km from St. Mary's Medical Center
6.6 out of 10, (989)
"It was good for the price I paid. "
United States
Felicity
The price is ฿2,793
฿3,249 total
includes taxes & fees
21 Jan - 22 Jan 2026
Alpha Inn & Suites
Desk, laptop workspace, blackout curtains, iron/ironing board
Rodeway Inn San Francisco City Center

Rodeway Inn San Francisco City Center

Rodeway Inn San Francisco City Center
2.0 star property
3 km from St. Mary's Medical Center
6.4 out of 10, (1000)
"Room was nice and clean. Parking a breeze."
United States
Mary
The price is ฿2,576
฿2,996 total
includes taxes & fees
11 Jan - 12 Jan 2026
Rodeway Inn San Francisco City Center
Superior Quadruple Room, Shared Bathroom, Park View (Golden Gate Park View)
Sunset Edwardian Bed and Breakfast at Golden Gate Park

Sunset Edwardian Bed and Breakfast at Golden Gate Park

Sunset Edwardian Bed and Breakfast at Golden Gate Park
2.0 star property
2.5 km from St. Mary's Medical Center
8.0 out of 10, Very good, (18)
"Very clean and safe, stores are within a walking distance, and the breakfast was complimentary, will be attended again"
United States
Khari
The price is ฿2,532
฿2,945 total
includes taxes & fees
4 Jan - 5 Jan 2026
Sunset Edwardian Bed and Breakfast at Golden Gate Park
Restaurant
Castle Inn

Castle Inn

Castle Inn
2.0 star property
Downtown San Francisco, 3.6 km from St. Mary's Medical Center
9.2 out of 10, Wonderful, (1002)
"Clean room, friendly staff, free parking a plus good place to stay "
United States
Jose
The price is ฿2,361
฿2,774 total
includes taxes & fees
6 Jan - 7 Jan 2026
Castle Inn
Exterior
LUMA Hotel San Francisco

LUMA Hotel San Francisco

LUMA Hotel San Francisco
4.0 star property
Mission Bay, 5.6 km from St. Mary's Medical Center
9.6 out of 10, Exceptional, (2401)
"Staff were so nice, the rooms were clean will definitely come back "
United States
Karla
The price is ฿6,172
฿7,264 total
includes taxes & fees
4 Jan - 5 Jan 2026
LUMA Hotel San Francisco
Exterior
Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA
4.0 star property
South of Market, 4.7 km from St. Mary's Medical Center
9.4 out of 10, Exceptional, (1309)
"Staff were helpful, kind and professional. The hotel was beautiful and easy to walk to restaurants, movies, and shopping."
United States
SHANNON
The price is ฿5,152
฿7,302 total
includes taxes & fees
30 Jan - 31 Jan 2026
Hyatt Regency San Francisco Downtown SOMA
Queen Room with Balcony and Ensuite | Desk, laptop workspace, free WiFi, bed sheets
Samesun San Francisco - Hostel

Samesun San Francisco - Hostel

Samesun San Francisco - Hostel
2.0 star property
Cow Hollow, 3.9 km from St. Mary's Medical Center
9.0 out of 10, Wonderful, (299)
"Comfortable beds, privacy, clean room"
United States
Corey
Samesun San Francisco - Hostel
Lobby sitting area
The Marker Union Square San Francisco

The Marker Union Square San Francisco

The Marker Union Square San Francisco
4.0 star property
3.9 km from St. Mary's Medical Center
9.0 out of 10, Wonderful, (1132)
"The staff was so fabulous, the hotel is gorgeous, and we are already having the best time!"
United States
Faith
The price is ฿4,632
฿5,452 total
includes taxes & fees
29 Jan - 30 Jan 2026
The Marker Union Square San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Mary's Medical Center Hotel Reviews

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

10/10 Excellent
"Food is good and staff friendly "
Clara 2-night trip
Posted 4 days ago
Hotel Riu Plaza Fisherman's Wharf

Hotels near other St. Mary's Medical Center attractions

Conservatory of Flowers

Admire the incredible array of blooms on display, from insect-eating plants to elaborately shaped orchids, at this well-preserved Victorian-era conservatory.
See properties

Jefferson Airplane House

Find out about the history of San Francisco when you spend time at Jefferson Airplane House. Discover the acclaimed art galleries and shops in this vibrant area.
See properties

Frequently asked questions

What's the area like around St. Mary's Medical Center?
St. Mary's Medical Center is located in San Francisco. If you're looking for a convenient place to stay, take a look at the 95 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to St. Mary's Medical Center?
Stanyan Park Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a coffee shop. It's located just a short 0.4 mi (0.7 km) from St. Mary's Medical Center. Other good options close by include The Metro Hotel and The Monte Cristo.
How many hotels can I expect to find near St. Mary's Medical Center?
Expedia has 95 hotels and other accommodation options within a mile from St. Mary's Medical Center.
If I need to cancel the hotel reservation for my stay near St. Mary's Medical Center, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near St. Mary's Medical Center.
What can I see and do near St. Mary's Medical Center?
California Academy of Sciences, De Young Museum and Walt Disney Family Museum feature a variety of fascinating exhibits to see while you're in town. Golden Gate Bridge, Full House House and Painted Ladies are some of the notable landmarks to see in the area. You can check out the local talent at The Fillmore, Louise Davies Symphony Hall and Bill Graham Civic Auditorium.
How can I get to St. Mary's Medical Center?
Nearby metro stations include Irving St & 9th Ave Stop, Irving St & 8th Ave Stop and Irving St & 7th Ave Stop. If you'd like to venture farther outside of the area, you may want a car rental for your journey.