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Our top choices for St. Luke's Hospital hotels

Indoor pool, seasonal outdoor pool
Marriott St. Louis West

Marriott St. Louis West

Marriott St. Louis West
3.5 star property
1.1 km from St. Luke's Hospital
8.4 out of 10, Very good, (1000)
"Needs to fix the heat "
United States
Falah
The price is ฿4,688
฿5,449 total
includes taxes & fees
15 Jan - 16 Jan 2026
Marriott St. Louis West
Breakfast, lunch, dinner served; American cuisine
Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
5 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (1001)
"Wonderful staff, easy parking, nice breakfast, very comfortable room."
United States
Carole
The price is ฿3,817
฿4,428 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hyatt Place St. Louis/Chesterfield
Exterior
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
5.1 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (1038)
"Absolutely amazing stay very nice play our family stays there every time very kid friendly"
United States
Matthew
The price is ฿4,034
฿4,679 total
includes taxes & fees
1 Jan - 2 Jan 2026
Drury Plaza Hotel St. Louis Chesterfield
Property amenity
Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
3.0 star property
7.3 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (199)
"Very clean and safe place, wonderful location "
United States
Ashley
The price is ฿5,866
฿6,862 total
includes taxes & fees
3 Jan - 4 Jan 2026
Residence Inn by Marriott St. Louis Chesterfield
Free daily buffet breakfast
Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur
3.0 star property
Creve Coeur, 5.3 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (1001)
"Excellent hotel! "
United States
Sara
The price is ฿3,561
฿4,139 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel St. Louis Creve Coeur
Lobby
AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield
3.5 star property
5.9 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (247)
"Newer hotel, very clean, up to date and in nice area. "
United States
Johnny
The price is ฿3,941
฿4,572 total
includes taxes & fees
4 Jan - 5 Jan 2026
AC Hotel by Marriott St. Louis Chesterfield
Exterior
Residence Inn by Marriott St. Louis West County

Residence Inn by Marriott St. Louis West County

Residence Inn by Marriott St. Louis West County
3.0 star property
6.5 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (245)
"Very dog friendly place to stay"
United States
William
The price is ฿4,301
฿4,946 total
includes taxes & fees
23 Jan - 24 Jan 2026
Residence Inn by Marriott St. Louis West County
Room, 2 Queen Beds | Desk, laptop workspace, blackout curtains, iron/ironing board
Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Fairfield Inn & Suites by Marriott St. Louis Chesterfield
3.0 star property
4.2 km from St. Luke's Hospital
9.0 out of 10, Wonderful, (1002)
"Rooms clean, pool area nice and warm, staff excellent."
United States
Demontra
The price is ฿3,139
฿3,641 total
includes taxes & fees
11 Jan - 12 Jan 2026
Fairfield Inn & Suites by Marriott St. Louis Chesterfield
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
14.9 km from St. Luke's Hospital
9.4 out of 10, Exceptional, (2763)
"Great place to stay before your early morning flight. "
United States
Henry
The price is ฿2,793
฿3,288 total
includes taxes & fees
1 Jan - 2 Jan 2026
Pear Tree Inn St. Louis Airport
Free daily buffet breakfast
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
13.4 km from St. Luke's Hospital
9.4 out of 10, Exceptional, (1005)
"Everything was great!"
United States
Rita
The price is ฿3,465
฿3,982 total
includes taxes & fees
25 Jan - 26 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior
Courtyard by Marriott St. Louis West County

Courtyard by Marriott St. Louis West County

Courtyard by Marriott St. Louis West County
3.0 star property
6.5 km from St. Luke's Hospital
9.0 out of 10, Wonderful, (454)
"Business friendly great staff."
United States
Elijah
The price is ฿4,070
฿4,680 total
includes taxes & fees
2 Jan - 3 Jan 2026
Courtyard by Marriott St. Louis West County
Ballroom
The Wildwood Hotel

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
13.6 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (1614)
"Great place!"
United States
Biju
The Wildwood Hotel
Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
12.7 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (1002)
"Staff and hotel were amazing"
United States
Allison
The price is ฿3,569
฿4,137 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel St. Louis St. Charles
Exterior
Residence Inn St Louis Westport

Residence Inn St Louis Westport

Residence Inn St Louis Westport
3.0 star property
7.8 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (411)
"Great room for the price. Breakfast was amazing and the staff is super friendly! "
United States
Jimmy
The price is ฿4,720
฿5,475 total
includes taxes & fees
9 Jan - 10 Jan 2026
Residence Inn St Louis Westport
Lobby
Drury Inn & Suites St. Louis Brentwood

Drury Inn & Suites St. Louis Brentwood

Drury Inn & Suites St. Louis Brentwood
3.0 star property
13.9 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (1001)
"Love this place "
United States
Timothy
The price is ฿3,972
฿4,718 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Inn & Suites St. Louis Brentwood
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
15 km from St. Luke's Hospital
9.4 out of 10, Exceptional, (842)
"Clean, would stay again."
United States
Eryka
The price is ฿3,139
฿3,851 total
includes taxes & fees
29 Dec - 30 Dec
Courtyard by Marriott St. Louis Brentwood
Exterior
TownePlace Suites by Marriott Brentwood

TownePlace Suites by Marriott Brentwood

TownePlace Suites by Marriott Brentwood
3.0 star property
14.7 km from St. Luke's Hospital
9.4 out of 10, Exceptional, (375)
"Staff was friendly and central location. "
United States
Demetrius
The price is ฿4,097
฿4,989 total
includes taxes & fees
15 Jan - 16 Jan 2026
TownePlace Suites by Marriott Brentwood
Exterior
Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport
2.5 star property
7.8 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (812)
"Everything was great "
United States
Alan
The price is ฿3,796
฿4,403 total
includes taxes & fees
2 Jan - 3 Jan 2026
Fairfield Inn & Suites St Louis Westport
Exterior
Holiday Inn St. Louis - Creve Coeur by IHG

Holiday Inn St. Louis - Creve Coeur by IHG

Holiday Inn St. Louis - Creve Coeur by IHG
3.0 star property
5.3 km from St. Luke's Hospital
8.8 out of 10, Excellent, (351)
"Overall great stay, very clean and updated. Would stay again. "
United States
Alisa
The price is ฿3,662
฿4,377 total
includes taxes & fees
27 Jan - 28 Jan 2026
Holiday Inn St. Louis - Creve Coeur by IHG
Lobby
Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur, 5.6 km from St. Luke's Hospital
8.8 out of 10, Excellent, (1002)
"Clean room and very helpful staff"
United States
Amy
The price is ฿3,786
฿4,401 total
includes taxes & fees
8 Jan - 9 Jan 2026
Courtyard by Marriott St Louis Creve Coeur
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top St. Luke's Hospital Hotel Reviews

Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur

10/10 Excellent
"Super clean room, great parking and quiet area. Staff at front desk was very helpful. "
Janice 1-night trip
Posted 5 days ago
Courtyard by Marriott St Louis Creve Coeur
Holiday Inn St. Louis - Creve Coeur by IHG

Holiday Inn St. Louis - Creve Coeur by IHG

10/10 Excellent
"The food was delicious, and your Chef was fast in completing orders. "
Rosie 1-night trip
Posted 3 weeks ago
Holiday Inn St. Louis - Creve Coeur by IHG

Hotels near other St. Luke's Hospital attractions

Bellerive Country Club

Enjoy a round of golf in St. Louis at Bellerive Country Club. Experience the area's acclaimed theatre scene and entertainment choices.
See properties

Bowlero Chesterfield

You can take time to visit Bowlero Chesterfield during your travels to Chesterfield. Visit the shops and top-notch restaurants in this family-friendly area.
See properties

Frequently asked questions

What's the area like around St. Luke's Hospital?
St. Luke's Hospital is located in St. Louis. Travellers love the area for its great live music scene and top museums. You'll find 94 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay near St. Luke's Hospital?
Marriott St. Louis West is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an indoor pool. It's located just a short 0.7 mi (1.1 km) from St. Luke's Hospital. Other good options within 5 miles include Sonesta ES Suites St. Louis - Chesterfield and Fairfield Inn & Suites by Marriott St. Louis Chesterfield.
How many hotels can I expect to find near St. Luke's Hospital?
Expedia has 94 hotels and other accommodation options a few miles from St. Luke's Hospital.
If I need to cancel the hotel reservation for my stay near St. Luke's Hospital, will I receive a refund?
Yes, most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get top deals close to St. Luke's Hospital.
What can I see and do near St. Luke's Hospital?
You'll want to browse the collections at Myseum, American Kennel Club Museum of the Dog and Historic Aircraft Restoration Museum. Get outside and spend some time strolling around Lou Fusz Soccer Complex, Sophia M. Sachs Butterfly House and Faust Park. Attractions like Chesterfield Arts and Chesterfield Amphitheater highlight the local culture.