A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

Search Luxury Hotels in St. Charles

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Charles Luxury Hotels

Next weekend
6 Nov - 8 Nov
In two weeks
13 Nov - 15 Nov

Our top choices for St. Charles luxury hotels

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

1. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1,003 reviews)
"Wonderful place to stay and great location!"
United States
Robert
The price is ฿4,897
฿5,677 total
includes taxes & fees
15 Nov - 16 Nov
Drury Plaza Hotel St. Louis St. Charles
A brick building with a sign reading "Country Inn & Suites."

2. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1,106 reviews)
"Very convenient to downtown St Charles. As per previous visits this hotel is excellent for the price range of the rooms."
United States
Stewart
The price is ฿4,304
฿4,946 total
includes taxes & fees
22 Nov - 23 Nov
Country Inn & Suites by Radisson, St. Charles Historic District
A modern meeting room with a long table, comfortable seating, and a brick wall backdrop.

3. Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
St. Charles
9.0 out of 10, Wonderful, (754 reviews)
"Great stay!"
United States
Sara
The price is ฿3,991
฿4,795 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites St. Charles Old Town Area
A multi-level hotel lobby with numerous seating areas, a central water feature, and a variety of plants.

4. Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,005 reviews)
"Great place to stay"
United States
Elyse
The price is ฿4,404
฿5,061 total
includes taxes & fees
22 Nov - 23 Nov
Embassy Suites by Hilton St. Louis St. Charles
A modern hotel with a prominent Hilton logo, multiple floors, and a well-lit entrance.

5. Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
St. Charles
8.6 out of 10, Excellent, (888 reviews)
"Check-in desk agents were wonderful and very knowledgeable about the area."
United States
Marvin
The price is ฿4,278
฿4,959 total
includes taxes & fees
22 Nov - 23 Nov
Tru by Hilton St. Charles St. Louis, MO
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,086 reviews)
"Great place"
United States
Samuel
The price is ฿5,377
฿6,845 total
includes taxes & fees
16 Nov - 17 Nov
Ameristar Casino Resort and Spa
A hotel with a prominent 'Comfort Suites' sign, a covered entrance with columns, and a parking lot.

7. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,000 reviews)
"Great stay."
United States
Bryan
The price is ฿3,138
฿3,607 total
includes taxes & fees
29 Nov - 30 Nov
Comfort Suites St Charles - St Louis
A spacious living room with a large sectional sofa, a coffee table, and a fireplace. There is a television mounted on the wall and a chandelier hanging from the ceiling.

8. Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
St. Charles
8.2 out of 10, Very good, (1,002 reviews)
"Hotel was clean and staff were super friendly. Breakfast was good and coffee bar was excellent!"
United States
Steven
The price is ฿2,943
฿3,411 total
includes taxes & fees
2 Nov - 3 Nov
Best Western Plus The Charles Hotel
A hotel room with a bed, a desk with two chairs, a TV, and a mirror.

9. Candlewood Suites St Louis St Charles by IHG

Candlewood Suites St Louis St Charles by IHG
2.5 star property
St. Charles
7.6 out of 10, Good, (830 reviews)
"Only stayed for 6 hours after returning from a trip but the staff who checked me in was awesome and v3ry helpful!!!"
United States
Jeffrey
The price is ฿3,006
฿3,455 total
includes taxes & fees
29 Nov - 30 Nov
Candlewood Suites St Louis St Charles by IHG
A spacious lobby with a reception desk, seating area, and a fireplace.

10. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
St. Charles
5.6 out of 10, (1,002 reviews)
"Staff was extremely accommodating and helpful"
United States
ROSE
The price is ฿3,377
฿3,915 total
includes taxes & fees
2 Nov - 3 Nov
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a door, and a wall with a road map mural.

11. Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.2 out of 10, Very good, (1,000 reviews)
"Clean room, staff was polite and helpful!"
United States
Tammie
The price is ฿2,699
฿3,102 total
includes taxes & fees
8 Nov - 9 Nov
Super 8 by Wyndham St Charles
A Holiday Inn Express & Suites hotel with a covered entrance and a brick facade.

12. Holiday Inn Express Hotel and Suites St. Charles by IHG

Holiday Inn Express Hotel and Suites St. Charles by IHG
3.0 star property
St. Charles
8.2 out of 10, Very good, (771 reviews)
"As always with a Holiday Inn property, our room was clean and very comfortable. The staff was very friendly. Breakfast was good and served hot."
United States
sharon
The price is ฿3,783
฿4,348 total
includes taxes & fees
27 Nov - 28 Nov
Holiday Inn Express Hotel and Suites St. Charles by IHG
A reception desk with a wooden counter, a computer, a telephone, and a small plant. There are three pendant lights above the desk.

13. Country Inn & Suites by Radisson, St. Peters, MO

Country Inn & Suites by Radisson, St. Peters, MO
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,004 reviews)
"Great location. Friendly staff decent breakfast."
United States
Heather
The price is ฿2,842
฿3,267 total
includes taxes & fees
29 Nov - 30 Nov
Country Inn & Suites by Radisson, St. Peters, MO
A swimming pool area with red and white lounge chairs, a glass table, and a blue and yellow ceiling.

14. Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,005 reviews)
"Fantastic place to stay! The staff was amazing!"
United States
Catherine
The price is ฿3,698
฿4,250 total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn St. Charles St. Peters
A reception area with a counter, a clock, a coffee station, and a seating area with chairs and a table.

15. Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
St. Charles
6.8 out of 10, (1,002 reviews)
"It was nice"
United States
Christoph
The price is ฿2,128
฿2,446 total
includes taxes & fees
2 Nov - 3 Nov
Relax Inn Saint Charles
A spacious lobby with a staircase, a reception desk, and a green wall with white floral patterns.

16. Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
St. Charles
5.8 out of 10, (564 reviews)
"Great stay!"
United States
Christine
The price is ฿2,459
฿2,826 total
includes taxes & fees
27 Nov - 28 Nov
Sleep Inn Saint Charles North
A multi-story hotel with a parking lot in front.

17. WoodSpring Suites St Louis St Charles

WoodSpring Suites St Louis St Charles
2.5 star property
St. Charles
5.6 out of 10, (308 reviews)
"Clean and staff was nice."
United States
Erica
The price is ฿2,871
฿3,299 total
includes taxes & fees
5 Nov - 6 Nov
WoodSpring Suites St Louis St Charles
A hotel room with a large bed, a desk, and a television.

18. Home2 Suites by Hilton St. Charles St.Louis

Home2 Suites by Hilton St. Charles St.Louis
3.0 star property
St. Charles
The price is ฿3,850
฿4,272 total
includes taxes & fees
2 Dec - 3 Dec
Home2 Suites by Hilton St. Charles St.Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top St. Charles Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

8/10 Good
"It was a lovely room, great location and I have no complaints. I would stay there again."
Margaretta 1-night trip
Posted 2 hours ago
Hyatt Regency St. Louis at The Arch

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Charles is 1172 mm.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.