Find hotels in Seneca, MO from ฿2,212

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
14 Dec - 15 Dec
Tomorrow
15 Dec - 16 Dec
Next weekend
19 Dec - 21 Dec
In two weeks
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Seneca hotels

Outdoor spa tub
La Quinta Inn & Suites by Wyndham Joplin

La Quinta Inn & Suites by Wyndham Joplin

La Quinta Inn & Suites by Wyndham Joplin
3.0 star property
Joplin
9.0 out of 10, Wonderful, (1483)
"Everything was phenomenal, especially the breakfast!"
United States
Peter
The price is ฿2,814
฿3,189 total
includes taxes & fees
5 Jan - 6 Jan 2026
La Quinta Inn & Suites by Wyndham Joplin
Lobby
Sleep Inn South Joplin

Sleep Inn South Joplin

Sleep Inn South Joplin
2.5 star property
Joplin
8.6 out of 10, Excellent, (674)
"Friendly staff, clean room. Good food, comfortable bed"
United States
Sanjayanand
The price is ฿2,811
฿3,186 total
includes taxes & fees
21 Dec - 22 Dec
Sleep Inn South Joplin
Exterior
Hampton Inn Miami

Hampton Inn Miami

Hampton Inn Miami
2.5 star property
Miami
9.2 out of 10, Wonderful, (1004)
"The staff was friendly and helpful and the entire hotel was clean. The breakfast offered was the best we have ever had at any hotel, including other Hampton Inns."
United States
Steve
The price is ฿2,751
฿3,150 total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn Miami
Basic Double Room, City View | Dining
Quality inn Neosho

Quality inn Neosho

Quality inn Neosho
2.0 star property
Neosho
9.4 out of 10, Exceptional, (3)
"Staff was very kind. There was a recent remodel and the rooms were nice. My family had 2 rooms and they were both remodeled. We'll definitely stay there in the future."
United States
Joey
The price is ฿2,776
฿3,133 total
includes taxes & fees
15 Dec - 16 Dec
Quality inn Neosho
Indoor pool
Drury Inn & Suites Joplin

Drury Inn & Suites Joplin

Drury Inn & Suites Joplin
3.0 star property
Joplin
9.2 out of 10, Wonderful, (1005)
"We love this hotel"
United States
justin
The price is ฿2,965
฿3,361 total
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites Joplin
Premium bedding, pillow-top beds, blackout curtains, iron/ironing board
Days Inn by Wyndham Miami

Days Inn by Wyndham Miami

Days Inn by Wyndham Miami
2.5 star property
Miami
7.2 out of 10, Good, (596)
"Solid option for what you pay"
United States
Jeff
The price is ฿1,931
฿2,211 total
includes taxes & fees
11 Jan - 12 Jan 2026
Days Inn by Wyndham Miami
Front of property
Plaza Motel

Plaza Motel

Plaza Motel
2.5 star property
Joplin
8.2 out of 10, Very good, (57)
"Had a nice stay"
United States
Retha
The price is ฿1,956
฿2,212 total
includes taxes & fees
15 Dec - 16 Dec
Plaza Motel
Interior entrance
River Bend Casino & Hotel

River Bend Casino & Hotel

River Bend Casino & Hotel
2.5 star property
Wyandotte
9.4 out of 10, Exceptional, (1001)
"Yes, stay was great!"
United States
Laura
The price is ฿2,356
฿2,545 total
includes taxes & fees
15 Dec - 16 Dec
River Bend Casino & Hotel
Indoor pool
Holiday Inn Express And Suites Joplin Southeast by IHG

Holiday Inn Express And Suites Joplin Southeast by IHG

Holiday Inn Express And Suites Joplin Southeast by IHG
2.5 star property
Joplin
8.2 out of 10, Very good, (563)
"Clean room, fully stocked and great variety at breakfast, nice staff! "
United States
Meghan
The price is ฿4,007
฿4,541 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express And Suites Joplin Southeast by IHG
Coffee service
Quality Inn Joplin I-44

Quality Inn Joplin I-44

Quality Inn Joplin I-44
2.5 star property
Joplin
8.4 out of 10, Very good, (1001)
"Great staff and very clean room and hotel! Breakfast was good!"
United States
Timothy
The price is ฿2,557
฿2,898 total
includes taxes & fees
13 Jan - 14 Jan 2026
Quality Inn Joplin I-44
Exterior
Booneslick Lodge of Neosho

Booneslick Lodge of Neosho

Booneslick Lodge of Neosho
2.0 star property
Neosho
7.8 out of 10, Good, (370)
"The room was clean and the price was very affordable."
United States
Jeramy
The price is ฿2,271
฿2,563 total
includes taxes & fees
15 Dec - 16 Dec
Booneslick Lodge of Neosho
Premium bedding, in-room safe, desk, iron/ironing board
Microtel Inn & Suites by Wyndham Miami

Microtel Inn & Suites by Wyndham Miami

Microtel Inn & Suites by Wyndham Miami
2.0 star property
Miami
7.0 out of 10, Good, (440)
"I stayed at the hotel for a week. There were a couple of minor maintenance issues with my room (light burned out & broken coffee pot) and the staff fixed them as soon as I notified them of the problem. The breakfast was very good. The service from the front desk and housekeeping were exceptional. The staff worked really hard to make my stay a pleasant experience. "
United States
Adrien
The price is ฿2,429
฿2,781 total
includes taxes & fees
15 Dec - 16 Dec
Microtel Inn & Suites by Wyndham Miami
Lobby
Fairfield Inn by Marriott Joplin

Fairfield Inn by Marriott Joplin

Fairfield Inn by Marriott Joplin
2.5 star property
Joplin
8.8 out of 10, Excellent, (474)
"Very easy check in and property was very clean. "
United States
William
The price is ฿3,663
฿4,151 total
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn by Marriott Joplin
Desk, laptop workspace, iron/ironing board, cots/infant beds
Best Western Big Spring Lodge

Best Western Big Spring Lodge

Best Western Big Spring Lodge
2.5 star property
Neosho
9.0 out of 10, Wonderful, (652)
"Was clean,good breakfast bar and coffee available all day."
United States
Cassandra
The price is ฿3,123
฿3,524 total
includes taxes & fees
21 Dec - 22 Dec
Best Western Big Spring Lodge
Lobby
Residence Inn Marriott Joplin

Residence Inn Marriott Joplin

Residence Inn Marriott Joplin
3.0 star property
Joplin
9.2 out of 10, Wonderful, (1001)
"Clean rooms!"
United States
Yvonne
The price is ฿3,541
฿4,048 total
includes taxes & fees
20 Dec - 21 Dec
Residence Inn Marriott Joplin
Lobby
Days Inn by Wyndham Joplin

Days Inn by Wyndham Joplin

Days Inn by Wyndham Joplin
2.0 star property
Joplin
7.0 out of 10, Good, (1002)
"Courteous staff and clean room. "
United States
Frances
The price is ฿2,118
฿2,401 total
includes taxes & fees
16 Dec - 17 Dec
Days Inn by Wyndham Joplin
Reception
Route 66 lnn & Suites

Route 66 lnn & Suites

Route 66 lnn & Suites
2.5 star property
Miami
8.0 out of 10, Very good, (91)
"Traveled with partner the location is quiet and convenient to all locations in town and to Joplin Missouri. Rooms very clean as were the property grounds, this is our second stay here and will be our go to location "
United States
Shirley Jean
The price is ฿3,345
฿3,830 total
includes taxes & fees
15 Dec - 16 Dec
Route 66 lnn & Suites
Room, 2 Queen Beds, Accessible, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Anderson

Econo Lodge Anderson

Econo Lodge Anderson
2.0 star property
Anderson
7.6 out of 10, Good, (414)
"Very comfy beds. "
United States
Nikki
The price is ฿2,172
฿2,351 total
includes taxes & fees
28 Dec - 29 Dec
Econo Lodge Anderson
Reception
Deluxe Inn & Suites By OYO Miami OK

Deluxe Inn & Suites By OYO Miami OK

Deluxe Inn & Suites By OYO Miami OK
2.0 star property
Miami
7.0 out of 10, Good, (245)
"Clean and comfortable "
United States
Frosty
The price is ฿1,766
฿2,243 total
includes taxes & fees
15 Dec - 16 Dec
Deluxe Inn & Suites By OYO Miami OK
Lobby
Homewood Suites by Hilton Joplin

Homewood Suites by Hilton Joplin

Homewood Suites by Hilton Joplin
3.0 star property
Joplin
9.6 out of 10, Exceptional, (760)
"Great place to stay and the staff is friendly "
United States
Kenji
The price is ฿4,013
฿4,538 total
includes taxes & fees
21 Dec - 22 Dec
Homewood Suites by Hilton Joplin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Seneca Hotel Reviews

Residence Inn Marriott Joplin

Residence Inn Marriott Joplin

10/10 Excellent
"Very good food "
Terry 1-night trip
Posted 2 weeks ago
Residence Inn Marriott Joplin
Holiday Inn Express And Suites Joplin Southeast by IHG

Holiday Inn Express And Suites Joplin Southeast by IHG

10/10 Excellent
"All of the above"
Michael 1-night trip
Posted 1 month ago
Holiday Inn Express And Suites Joplin Southeast by IHG

More cheap stays in Seneca

Days Inn by Wyndham Joplin

Days Inn by Wyndham Joplin

3500 South Rangeline RD Joplin MO
The price is ฿2,118 per night from 16 Dec to 17 Dec
฿2,118
฿2,401 total
16 Dec - 17 Dec
includes taxes & fees
6.8/10 (1,001 reviews)

Frequently asked questions

What's the best place for a stay in Seneca?
Located 16.4 mi (26.3 km) from the heart of Seneca, La Quinta Inn & Suites by Wyndham Joplin is a top choice for your stay, based on our traveller data. Other good options for your stay in the area are Days Inn by Wyndham Joplin and River Bend Casino & Hotel. See all available top hotels, or vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes! Most hotel bookings are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What is staying in Seneca like?
Visitors can enjoy all that Seneca has to offer, including its casinos. There are 262 hotels and other accommodation options in the surrounding area. Find out more about Seneca.
What is there to see in Seneca?
Places to visit in the wider area include Indigo Sky Casino, Downstream Casino Resort and Buffalo Run Casino. You'll also find Miami Tribe Entertainment & Gaming and Stables Casino in the area. Take a look at what more there is to see and do in Expedia's Seneca guide.
What's the weather like in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Seneca is 1319 mm.

Explore a world of travel with Expedia