Find hotels in Santa María Mixtequilla from ฿1,133

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa María Mixtequilla hotels

Hotel Calli

Hotel Calli
3.5 star property
Tehuantepec
9.0 out of 10, Wonderful, (90)
Explore Tehuantepec culture from this hotel near the House of Culture and Guiengola. Enjoy the outdoor pool, grab refreshments at the café, or relax with a drink at the bar. The garden and terrace create a tranquil setting with free WiFi and parking.

"Property was nice and well maintained. Nice outside pool. Breakfast was available for a price. "
United States
Angel
The price is ฿1,712
฿2,037 total
includes taxes & fees
24 Dec - 25 Dec
Hotel Calli

Hotel Express Inn Juchitan

Hotel Express Inn Juchitan
2.5 star property
Juchitan de Zaragoza
7.8 out of 10, Good, (19)
Relax at this entertainment district hotel with comforting amenities like free WiFi and parking. After exploring nearby Jardín Juárez, unwind with a drink at the bar or enjoy a bite at the café. The 24-hour front desk ensures seamless service.

"Ok"
Mexico
obed
Hotel Express Inn Juchitan

Hotel Boutique Alebrijes Salina Cruz

Hotel Boutique Alebrijes Salina Cruz
3.0 star property
Salina Cruz
9.4 out of 10, Exceptional, (18)
Colourful Mexican-inspired property with a refreshing outdoor pool near the Zocalo and Malecón. This hotel offers convenient amenities including free WiFi, complimentary parking, and a café for quick bites after exploring nearby attractions.

"The room was clean and the housekeeping lady was friendly and helpful."
United States
Jaymie
The price is ฿1,379
฿1,641 total
includes taxes & fees
24 Dec - 25 Dec
Hotel Boutique Alebrijes Salina Cruz

Sicarú

Sicarú
2.0 star property
Salina Cruz
9.0 out of 10, Wonderful, (14)
This welcoming hotel offers daily housekeeping and attentive front desk support around the clock. Just moments from Zocalo of Salina Cruz and the scenic Malecón waterfront, guests enjoy convenient access to the city's main attractions.

"Very clean, comfortable, and well located hotel in the heart of downtown Salina Cruz, Oaxaca, México. Nice price, very acceptable."
Mexico
John
The price is ฿1,212
฿1,442 total
includes taxes & fees
23 Jan - 24 Jan 2026
Sicarú

Hotel Central

Hotel Central
3.0 star property
Juchitan de Zaragoza
8.6 out of 10, Excellent, (87)
This welcoming hotel combines practical amenities like free WiFi and 24-hour front desk service with thoughtful extras. Garden spaces offer tranquil moments, while business travellers appreciate the round-the-clock business centre and bike cleaning facilities.

"Perfect hotel!"
Belgium
Lukas
The price is ฿1,350
฿1,607 total
includes taxes & fees
23 Jan - 24 Jan 2026
Hotel Central

City Express by Marriott Salina Cruz

City Express by Marriott Salina Cruz
3.5 star property
Salina Cruz
8.4 out of 10, Very good, (308)
This business-friendly hotel offers an outdoor pool for morning swims and a fitness centre for workouts. Enjoy free breakfast, WiFi, and parking while exploring the nearby Zocalo and Malecón Salina Cruz waterfront.

"Excelente"
Mexico
Yeeviani
The price is ฿1,781
฿2,120 total
includes taxes & fees
31 Dec - 1 Jan 2026
City Express by Marriott Salina Cruz

One Salina Cruz

One Salina Cruz
3.0 star property
Salina Cruz
9.0 out of 10, Wonderful, (424)
Business travellers will appreciate this hotel's strategic position near the train station and the Zocalo of Salina Cruz. Complimentary perks include daily buffet breakfast, WiFi, and parking, while the Malecón waterfront promenade awaits nearby for leisure moments.

"Excelente "
Mexico
Elizabeth Yazmin
The price is ฿1,633
฿1,944 total
includes taxes & fees
4 Jan - 5 Jan 2026
One Salina Cruz

Hotel Santa Cruz Juchitan

Hotel Santa Cruz Juchitan
3.0 star property
Juchitan de Zaragoza
7.8 out of 10, Good, (111)
Set in Juchitan de Zaragoza, this welcoming hotel offers convenient amenities including free WiFi and parking. Just minutes from the charming Jardín Juárez and featuring 24-hour front desk service for travellers seeking authentic local exploration.

"Being the only hotel in town, it was fine."
United States
Tony
Hotel Santa Cruz Juchitan

Bungalows Punta Conejo

Bungalows Punta Conejo
3.0 star property
Salina Cruz
9.2 out of 10, Wonderful, (10)
This beachside hotel offers relaxing massages and a tranquil garden setting. Just minutes from Playa Brasil and Playa Azul, guests enjoy convenient amenities including free WiFi, parking, and an inviting coffee shop for refreshments.

"The shower had a very bad water flow. When we arrived, there were no towels and toilet-paper in the room. At the end we could almost not pay with our creditcard (raison ??) But the breakfast was very good! Thank you"
Mexico
Hans
The price is ฿1,558
฿1,854 total
includes taxes & fees
23 Jan - 24 Jan 2026
Bungalows Punta Conejo

Casa de Huéspedes Juanita

Casa de Huéspedes Juanita
2.5 star property
Salina Cruz
7.2 out of 10, Good, (17)
Modern accommodation near Zocalo and Malecón Salina Cruz with free WiFi and a health club. This hotel offers convenient amenities including a 24-hour front desk to enhance your stay in this coastal Mexican destination.

"To rest its okay, there’s nothing to enjoy or feel surprised by the are. "
United States
Juana
The price is ฿952
฿1,133 total
includes taxes & fees
24 Dec - 25 Dec
Casa de Huéspedes Juanita

Hotel Express Inn Ixtepec

Hotel Express Inn Ixtepec
3.0 star property
Ixtepec
7.4 out of 10, Good, (54)
Located in the heart of Ixtepec, this welcoming hotel offers free WiFi and round-the-clock front desk service. Just 35 minutes from Ixtepec Airport, enjoy comfortable accommodation with breakfast available to fuel your Oaxaca adventures.

"Express Inn is quiet , clean , and comfortable. The location is great for dining and shopping. A very fun little town "
United States
Tami
Hotel Express Inn Ixtepec

Hotel De La Peña Inn

Hotel De La Peña Inn
3.0 star property
Santa María
8.2 out of 10, Very good, (36)
Tropical garden surroundings complement this Tehuantepec hotel with an inviting outdoor pool. Savour a meal at the on-site restaurant after exploring nearby House of Culture and Guiengola. Free WiFi and parking enhance the experience.

"Highly recommend this place for the price. Friendly professional staff. Clean room and super comfy bed. Nice bathroom. The location is a little odd being on a sort of roundabout, but as I was in town to visit the ruins of Guiengola it was ideal for me. Can't fault the plaxe "
United Kingdom
Ralph
Hotel De La Peña Inn

Punta Conejo Resort

Punta Conejo Resort
3.0 star property
Salina Cruz
7.2 out of 10, Good, (12)
"If you want to get off the grid and feel isolated with ocean front accommodations, this is the spot . "
United States
Anonymous traveller
Punta Conejo Resort

Casa Majeva

Casa Majeva
3.0 star property
Salina Cruz
10.0 out of 10, Exceptional, (3)
Unwind in this welcoming Oaxaca retreat with an outdoor pool and on-site restaurant. Just minutes from Las Escolleras Beach and Playa Brasil, the hotel offers free WiFi and round-the-clock front desk assistance for seamless exploration.

"The property is truly a gem in quite a remote area. As it is a non season, everything is closed, but this hotel is working and that is nice. But actually besides its teritory there is nothing to do there. The owner is extremely nice and chatty! It gives property a lot if charm. Other staff members unfortunatelly really dont speak english much so the communication is very limited. Well, almost like in all Mexico. Overall nice pool and interior in the apartments, would be great to have some...
United States
Vismante
The price is ฿3,687
฿4,387 total
includes taxes & fees
25 Dec - 26 Dec
Casa Majeva

Hotel Calendas

Hotel Calendas
2.5 star property
Salina Cruz
7.8 out of 10, Good, (27)
This laid-back lodge offers convenient amenities near Zocalo and Malecón Salina Cruz. Enjoy complimentary WiFi and parking while exploring local attractions. The 24-hour front desk ensures assistance is always available during your coastal getaway.

"The antique look and all the beautiful historical pictures"
United States
Veronica
The price is ฿1,371
฿1,632 total
includes taxes & fees
23 Jan - 24 Jan 2026
Hotel Calendas

HOTEL CASA TERESA GALERIA CAFE

HOTEL CASA TERESA GALERIA CAFE
3.0 star property
Juchitan de Zaragoza
7.2 out of 10, Good, (18)
Immerse in local culture at this unique hotel with an art gallery and café. Enjoy complimentary continental breakfast and WiFi while staying near Jardín Juárez. Room service adds convenience for a relaxing Mexican getaway.

"Very nice owners who helped us in many ways including personally driving us to the bus station when our taxi did not arrive on time to make sure we did not miss our bus to San Cristobal."
United States
jeffrey
HOTEL CASA TERESA GALERIA CAFE

Hotel San Francisco

Hotel San Francisco
2.5 star property
Salina Cruz
8.0 out of 10, Very good, (96)
Unwind at this hotel located near the Zocalo and Malecón Salina Cruz. Take advantage of the 24-hour front desk service, complimentary WiFi, and free parking while enjoying the convenience of being right next to a stunning golf course.

"One scorpion in the towel up my bed "
United States
Mariano
The price is ฿1,388
฿1,651 total
includes taxes & fees
12 Jan - 13 Jan 2026
Hotel San Francisco

Gran Hotel Don Nacho

Gran Hotel Don Nacho
3.5 star property
Salina Cruz
7.2 out of 10, Good, (27)
Unwind at this welcoming retreat featuring hot stone massages and a poolside bar. Enjoy free WiFi and parking while staying near Zocalo and Malecón Salina Cruz. An outdoor pool and 24-hour fitness centre enhance your coastal Mexico experience.

"Excelente "
Mexico
Javier
The price is ฿2,786
฿3,315 total
includes taxes & fees
10 Jan - 11 Jan 2026
Gran Hotel Don Nacho
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa María Mixtequilla Hotel Reviews

More cheap stays in Santa María Mixtequilla

Frequently asked questions

What's the best place to stay in Santa María Mixtequilla?
One Salina Cruz, located 14.1 mi (22.7 km) from the heart of Santa María Mixtequilla, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are City Express by Marriott Salina Cruz and Hotel Central. See all available top hotels, or vacation rentals in Santa María Mixtequilla.
If I need to cancel my hotel reservation in Santa María Mixtequilla, will I receive a refund?
Yes! Most hotel reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa María Mixtequilla.
What is staying in Santa María Mixtequilla like?
Travellers to Santa María Mixtequilla will find plenty to explore and enjoy. There are 23 hotels and other accommodation options in the surrounding area. Find out more about Santa María Mixtequilla.
What should I see while I'm in Santa María Mixtequilla?
Places to visit in the wider area include Tehuantepec House of Culture, Las Escolleras Beach and Jardín Juárez. You'll also find Salina Cruz Lighthouse and Guiengola Archaeological Site in the area. Take a look at what more there is to see and do in Expedia's Santa María Mixtequilla guide.
What's the seasonal weather in Santa María Mixtequilla?
The hottest months are usually May and April, with an average temperature of 28°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in Santa María Mixtequilla are September, June, August and July, with each month seeing an average of 191 mm of rainfall.