Santa Fe de Antioquia Travel Guide

Tourist Guide

A historic fountain with water jets, surrounded by lush greenery and a white church with a bell tower in the background.
A street with buildings, a motorcycle, a tricycle, and a mountain in the background.
A vintage-themed living room with a large arched wall, a vintage camera, a red armchair, a wooden cabinet, and a large black and white portrait.
A colorful bus with 'La Santafrenia' written on it parked in front of a building with a tiled roof.
A white tuk-tuk parked on a cobblestone street in a historic town.

Where to stay in Santa Fe de Antioquia

Find the best Santa Fe de Antioquia areas for the activities you enjoy most.
A narrow street flanked by white buildings with green shutters, a clear sky, and mountains in the background.
Photo by Botak Jon
Open Photo by Botak Jon

Zona Colonial

While visiting Zona Colonial, you might make a stop by sights like Cathedral of Santa Fe de Antioquia and Bolivar Square.

Ivanna Hotel Campestre - Santa Fe de Antioquia

Ivanna Hotel Campestre - Santa Fe de Antioquia

4.5 out of 5
Via Anza Vereda, KM 1, Obregon Santa Fe de Antioquia Antioquia
The price is ฿2,413 per night from 2 Sept to 3 Sept
฿2,413
฿2,413 total
2 Sept - 3 Sept
Stay at this luxury hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and 2 outdoor pools. Popular attractions Bolivar Square and Cathedral of ...
Ivanna Hotel Campestre - Santa Fe de Antioquia
Arde La Selva

Arde La Selva

4 out of 5
km 1 via anza vereda obregon Santa Fe de Antioquia Antioquia
The price is ฿5,771 per night from 30 Aug to 31 Aug
฿5,771
฿5,771 total
30 Aug - 31 Aug
Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Bolivar Square and Cathedral of Santa Fe ...
Arde La Selva
Entrecielos

Entrecielos

3 out of 5
Carrera 9 Santa Fe de Antioquia
The price is ฿2,411 per night from 28 Aug to 29 Aug
฿2,411
฿2,411 total
28 Aug - 29 Aug
Stay at this hotel in Santa Fe de Antioquia. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Bolivar Square and Casa Atanasio Girardot ...
9/10 Wonderful! (51 reviews)
"Very lovely stay, friendly staff, comfy bed and two really nice pools. Because Santa Fe de Antioquia is so hot, keep in mind, the showers don’t come equipped with hot water."

Reviewed on 12 Aug 2026

Entrecielos
See all 529 properties in Santa Fe de Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Finca hotel mi refugio

Finca hotel mi refugio

2 out of 5
1541 Camino real Santa Fé de Antioquia Antioquia
Stay at this cottage in Santa Fe de Antioquia. Enjoy free Wi-Fi, free parking and a garden. Popular attractions Bolivar Square and Cathedral of Santa Fe de Antioquia ...
Finca hotel mi refugio
SANTA FE DE ANTIOQUIA

SANTA FE DE ANTIOQUIA

2 out of 5
111 Cl. 8 Santa Fe de Antioquia Antioquia
Stay at this aparthotel in Santa Fe de Antioquia. Enjoy free Wi-Fi, 6 outdoor pools and a garden. Popular attractions Bolivar Square and Cathedral of Santa Fe ...
8/10 Very good! (1 review)
"Todo Ok"

Reviewed on 10 Feb 2025

SANTA FE DE ANTIOQUIA
Otalu Suites

Otalu Suites

3 out of 5
Diagonal 80A #45E 09 Medellín Antioquia
Stay at this apartment in Medellín. Enjoy free Wi-Fi, a fitness centre and a 24-hour front desk. Popular attractions Atanasio Giradot Stadium and Botero Plaza ...
Otalu Suites
See all properties in Santa Fe de Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Fe de Antioquia attractions

Bridge of the West

9.0/10 (19 reviews)
After visiting Bridge of the West, make a plan to see the other sights and activities in Santa Fe de Antioquia. Make time to visit the cathedral and monuments while you're in the area.
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Things to do

Santa Fe de Antioquia Tour with Western Bridge Visit

Santa Fe de Antioquia Tour with Western Bridge Visit

฿1,836
per adult
Santa Fe de Antioquia Tour with Western Bridge Visit
Coffee tour in Medellín with tastings and transportation

Coffee tour in Medellín with tastings and transportation

฿2,482
per adult
100% of travellers recommend
Coffee tour in Medellín with tastings and transportation
Tour Santa Fe de Antioquia

Tour Santa Fe de Antioquia

฿4,964
per adult
Tour Santa Fe de Antioquia
Private Coffee & Panel Tour Near Medellin All Inclusive

Private Coffee & Panel Tour Near Medellin All Inclusive

฿4,964
per adult
Private Coffee & Panel Tour Near Medellin All Inclusive
Horseback Riding Tour and Coffee Tour with Lunch and Refreshment

Horseback Riding Tour and Coffee Tour with Lunch and Refreshment

฿3,044
per adult
Horseback Riding Tour and Coffee Tour with Lunch and Refreshment
Santa Fe de Antioquia + Coffee Sightseeing Tour from Medellín, Private Tour

Santa Fe de Antioquia + Coffee Sightseeing Tour from Medellín, Private Tour

฿4,898
per adult
Santa Fe de Antioquia + Coffee Sightseeing Tour from Medellín, Private Tour
See all activities in Santa Fe de Antioquia