Santa Cruz Island Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ฿27,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Santa Cruz Island

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
The price is ฿5,320 per night from 29 Oct to 30 Oct
฿5,320
฿5,320 total
29 Oct - 30 Oct
9/10 Wonderful! (452 reviews)
"Great place"

Reviewed on 24 Oct 2026

Hotel Fiesta
Maidith Galapagos Inn

Maidith Galapagos Inn

3 out of 5
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
The price is ฿3,940 per night from 29 Oct to 30 Oct
฿3,940
฿3,940 total
29 Oct - 30 Oct
10/10 Exceptional! (172 reviews)
"I loved absolutely everything about the Maidith. The rooms are impeccable, the breakfast was delicious, the proprietors made us feel at home. He gave us great advice about tours, places to go and things to do. I wouldn't stay anywhere else in Puerto Ayora!"

Reviewed on 26 Oct 2026

Maidith Galapagos Inn
El Barranco Galapagos

El Barranco Galapagos

2.5 out of 5
Los colonos Puerto Ayora Galapagos
The price is ฿8,816 per night from 6 Nov to 7 Nov
฿8,816
฿8,816 total
6 Nov - 7 Nov
El Barranco Galapagos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Cruz Island attractions

What to do in Santa Cruz Island

Frequently asked questions

How much does a Santa Cruz Island holiday package cost?
From as low as . Yes, you read that right. Our Santa Cruz Island packages are a simple way to stretch your budget. Combine your preferred flights, hotels and rental car and explore this vibrant destination.
How do I get a cheap travel package to Santa Cruz Island?
Simply by bundling. Hotels, rental cars and flights — combine whatever you need into a Santa Cruz Island holiday package to save a ton of cash. Score even more discounts when you include extras such as sightseeing tours to your booking. But that's not the only good part. You have the flexibility to tailor your trip your way. We offer over 550 airlines and 1,000,000 properties throughout the world, so that everyone has an opportunity to travel and fulfil those holiday dreams.
How far in advance should I book my Santa Cruz Island holiday?
Reserving your flight early with Expedia means one less thing to worry about. Many air carriers advertise prices up to 12 months prior to take off. This is generally the cheapest time to book. If circumstances have left you booking late, discount flights to Santa Cruz Island sometimes occur a few weeks before departure.
What does an Expedia Santa Cruz Island travel package include?
Choose from any combination of rental cars, flights and hotels. Once you've made your booking, you can add activities and tours. Want to pick your fare class? That's also easy to do. The choice is yours when it comes to arranging your dream Santa Cruz Island getaway.
What should I know before booking a Santa Cruz Island travel package?
We already have low prices. However, you'll pick up even more savings when you book your hotels, flights and car rentals together. With an Expedia package, you'll always get transparent pricing and a terrific range of choice.
Can I choose my airline with a Santa Cruz Island Expedia holiday package?
You can. We offer more than 550 airline partners globally, so select the carrier that best fits your budget and travelling style.
If I'm not able to travel, can I cancel my Santa Cruz Island holiday package?
Yes, you can. We get that life doesn't always go to plan, so we're here to help if you need to make changes to your Santa Cruz Island holiday package. It may be possible to amend or cancel your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may charge you a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for further information. Also, check your itinerary for the finer details on change fees.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.