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16 Aug - 17 Aug
Tomorrow
17 Aug - 18 Aug
Next weekend
21 Aug - 23 Aug
In two weeks
28 Aug - 30 Aug

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Our top choices for San Francisco hotels

Reserve now, pay later
Breakfast included
Hotel
Spa
Hostel/Backpacker accommodation
Outdoor pool
Exterior
Front of property
Deluxe Single Room | Desk, laptop workspace, free WiFi

1. HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena
United States
Eduardo
฿2,535
฿2,789 total
includes taxes & fees
17 Aug - 18 Aug
HOTEL VISTA LAGO
Outdoor pool, free pool cabanas, pool umbrellas
Interior detail
Interior entrance
Exterior

2. Hotel Gran David

Hotel Gran David
Santiago
United States
Roxani
฿1,968
฿2,165 total
includes taxes & fees
17 Aug - 18 Aug
Hotel Gran David
3 outdoor pools, free pool cabanas, pool umbrellas
Lobby sitting area
Front of property
3 outdoor pools, free pool cabanas, pool umbrellas

3. Hotel Mykonos Panama

Hotel Mykonos Panama
Nuevo Santiago
United States
Ismael
฿3,314
฿3,646 total
includes taxes & fees
17 Aug - 18 Aug
Hotel Mykonos Panama
Interior
Interior
Junior Studio Suite | Interior
Shower, towels

4. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
Nuevo Santiago
United States
James
฿1,521
฿1,673 total
includes taxes & fees
24 Aug - 25 Aug
Hotel Plaza Los Tucanes
Restaurant
Exterior
Terrace/patio
Basic Cabin, 2 Queen Beds | Free WiFi, individually decorated, individually furnished, bed sheets

5. Hotel Anachoreo

Hotel Anachoreo
Santa Fe
United States
John
฿2,802
฿3,083 total
includes taxes & fees
17 Aug - 18 Aug
Hotel Anachoreo
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Top San Francisco Hotel Reviews

Hotel Gran David

Hotel Gran David

10/10 Excellent
"Limpio todo y el desayuno variado"
Paola 1-night trip
Posted 3 days ago
Hotel Gran David
HOTEL VISTA LAGO

HOTEL VISTA LAGO

10/10 Excellent
"We went to this hotel for the first time and it’s so amazing, excellent food nothing else to add"
Christian 1-night trip
Posted 13 days ago
HOTEL VISTA LAGO
Hotel Mykonos Panama

Hotel Mykonos Panama

10/10 Excellent
"Very well located"
Ismael 1-night trip
Posted 2 weeks ago
Hotel Mykonos Panama
Hotel Anachoreo

Hotel Anachoreo

8/10 Good
"Great property location and beautiful views, room and bath areas great. Breakfast was solid. Hot water was very inconsistent, usually cold. WiFi great"
michael 1-night trip
Posted 3 weeks ago
Hotel Anachoreo
Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes

10/10 Excellent
"👌"
Franklin 1-night trip
Posted 1 month ago
Hotel Plaza Los Tucanes
Hotel Galería

Hotel Galería

10/10 Excellent
"Hay un restaurante en el hotel con desayuno y comida económica y muy sabrosa. La ubicación del hotel es muy céntrica. Es seguro. Tiene centro comercial al lado. Parqueo de carro seguro. Es perfecto para una visita a Santiago."
Lionel 1-night trip
Posted 5 months ago
Hotel Galería

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Frequently asked questions

What's the best place for a stay in San Francisco?
Hotel Gran David, located 9.5 mi (15.4 km) from the heart of San Francisco, is a top choice for your stay, based on our traveller data. Other good options for your stay in the area are Hotel Mykonos Panama and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in San Francisco.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in San Francisco.
What is staying in San Francisco like?
Visitors to San Francisco will definitely find plenty to explore and enjoy. There are 18 hotels and other accommodation options in the surrounding area. Find out more about San Francisco.
What should I see while I'm in San Francisco?
Places to visit in the wider area include Laguna de La Yeguada, Parque Acuatico Italia Guadalupe Panama and Los Pozos Termales. You'll also find Omar Torrijos Herrera Stadium and Plaza Banconal in the area. Take a look at what more there is to see and do in Expedia's San Francisco guide.
What's the seasonal weather like in San Francisco?
The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in San Francisco are October, August, June and November, with each month seeing an average of 447 mm of rainfall.