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Find hotels in Pythagorio from ฿2,093

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Our top choices for Pythagorio hotels

Scorpios Hotel & Suites

Scorpios Hotel & Suites
3.0 star property
Samos
8.8 out of 10, Excellent, (19)
Discover Greek island tranquility at this Samos aparthotel near Gagou Beach. Elegant apartments feature Egyptian cotton sheets and Select Comfort beds. Refresh at the seasonal outdoor pool before enjoying drinks at the beach bar.

"It has a very nice view to the ocean and great quality of services "
Mexico
Karla
The price is ฿2,367
฿2,648 total
includes taxes & fees
15 Dec - 16 Dec
Scorpios Hotel & Suites

Samos Hotel

Samos Hotel
3.0 star property
Samos
7.6 out of 10, Good, (231)
Enjoy island tranquility at this Samos hotel offering an outdoor pool with poolside bar. Unwind with drinks from the bar/lounge or grab a bite at the café. Just minutes from Port of Samos, the hotel includes free WiFi, parking, and 24-hour fitness access.

"Central location Extremely small rooms for two single beds. "
United States
Phyllis
The price is ฿2,400
฿2,685 total
includes taxes & fees
15 Dec - 16 Dec
Samos Hotel

Villa of the old olive oil factory

Villa of the old olive oil factory
Samos
8.0 out of 10, Very good, (6)
"Service de ménage catastrophique mais proprietaire reactif suite a des problemes d enlèvement des courses personnelles lors d un passage"
France
Bruno Michel
Villa of the old olive oil factory

Hotel Aria

Hotel Aria
1.0 star property
Samos
6.6 out of 10, (30)
Just steps from Samos Port, this well-maintained hotel offers easy access to the Samos Archaeological Museum. Enjoy a drink at the bar after exploring nearby attractions. Free WiFi and parking enhance your Greek island stay.

"uygun fiyata merkezi yerde sadece uyumak için ideal bir otel. İşletmecisi orta yaşlarda bir teyze çok tatlı ve misafirperver... "
Turkey
Nuran
Hotel Aria

Erato by Samian Mare

Erato by Samian Mare
4.0 star property
Samos
9.2 out of 10, Wonderful, (17)
Experience Samos Island charm at this spa hotel featuring 2 outdoor pools and a poolside bar. Enjoy local cuisine at Samian Mare Restaurant, then relax with deep-tissue massages. The Karlovasi museums are nearby, with free breakfast, WiFi and parking included.

"Great stay! The staff was very helpful with booking taxis for us. The breakfast was great too!"
United States
Anonymous traveller
The price is ฿3,864
฿4,344 total
includes taxes & fees
15 Dec - 16 Dec
Erato by Samian Mare

Aegeon

Aegeon
3.0 star property
Samos
7.6 out of 10, Good, (19)
Bask in Mediterranean charm at this coastal haven near Karlovasi Tannery Museum. After enjoying the complimentary breakfast, unwind by the outdoor pool or indulge in massages. The restaurant, poolside bar, and free parking enhance your Greek island experience.

"Great pool & outdoor area with a lovely bar"
Australia
Tracey
The price is ฿1,860
฿2,093 total
includes taxes & fees
7 Jan - 8 Jan 2026
Aegeon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Pythagorio attractions

Learn more about Pythagorio

The ancient harbour town showcases Pythagoras' legacy at its archaeological museum and the impressive remains of Tunnel of Eupalinos. Waterfront tavernas serve fresh seafood beside bobbing fishing boats, while nearby beaches offer perfect swimming spots.

Energy limonate😋👌
Photo by Erdem Yücel
Open Photo by Erdem Yücel

Top Pythagorio Hotel Reviews

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Frequently asked questions

What's the best place to stay in Pythagorio?
Casa Cook Samos is ranked highly by Expedia customers. This hotel offers a full-service spa and 2 bars. Another favourite option for your stay based on traveller reviews is Glicorisa Beach. See all available top hotels, or vacation rentals in Pythagorio.
If I need to cancel my hotel reservation in Pythagorio, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Pythagorio.
What's the best family accommodation in Pythagorio?
Anna Studios is a guesthouse with child-friendly meals and free WiFi, and it's a top choice on Expedia for families. Also, attractions in the area such as Natural History Museum of the Aegean are fun for the whole family. Find more child-friendly accommodations in Pythagorio.
What is the favourite LGBTQ-friendly accommodation in Pythagorio?
Sama is a top LGBTQ-friendly hotel and features private balconies. See all available hotels listed as LGBTQ-friendly in Pythagorio.
What's the best dog-friendly place to stay in Pythagorio?
Casa Cook Samos is a top hotel for people travelling with their pets, and offers a full-service spa and free WiFi for its human guests. Other good choices for you and your pet's trip include Doryssa Boutique Hotel and Nisea Hotel Samos. See more pet-friendly hotel accommodations in Pythagorio.
What's the best accommodation option for a beach holiday in Pythagorio?
Casa Cook Samos is a top beachfront hotel with a seasonal outdoor pool and free breakfast, and it's located close to Potakaki beach . Other good options for your beach trip include Proteas Blu Resort - Adults Only and Doryssa Seaside Resort. See more stays near the beach in Pythagorio.
What's the best luxury hotel in Pythagorio?
Casa Cook Samos is a luxury hotel with a beachfront restaurant and 2 bars, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Proteas Blu Resort - Adults Only and Doryssa Seaside Resort are other upscale choices for your holiday. Find more luxury hotels in Pythagorio.
What's the best boutique-style hotel in Pythagorio?
Casa Cook Samos is a favourite hotel with Expedia travellers looking for a stylish stay, and features a beachfront restaurant and 2 bars. Doryssa Boutique Hotel and Naftilos are other boutique-style choices. See all boutique hotels in Pythagorio.
What are some accommodation options with pools in Pythagorio?
Proteas Blu Resort - Adults Only is a top hotel with an indoor pool, an outdoor pool and a private beach. View all hotels with pools in Pythagorio.
What is the best spa hotel in Pythagorio?
Casa Cook Samos is a top beach spa hotel featuring a fitness centre, a hair salon, a beach bar and a restaurant. Treat yourself to a facial, body scrub or Swedish massage at the on-site spa. In-room massages are also available. Other popular spa hotels in Pythagorio include Proteas Blu Resort - Adults Only and Doryssa Seaside Resort. See all spa hotels in Pythagorio.
What's it like staying in Pythagorio?
Visitors to Pythagorio will definitely enjoy the seaside. Tourists can also enjoy the city's monuments, museums and gardens. In Pythagorio, there are 74 hotels and other accommodation options to choose from. Find out more about Pythagorio.
What are the top places to visit in Pythagorio?
Cultural venues include Folklore Museum of Samos, Nikolaos Dimitriou Folklore Museum and Folklore Museum of the Nikolaos Dimitriou Foundation of Samos. Landmarks like Pythagoreion, Heraion of Samos and Castle of Lycurgus might be worth a visit. Natural beauty is on display at Glicorisa Beach, Mykali Beach and Papa Beach. Take a look at what more there is to see and do in Expedia's Pythagorio guide.
What's the seasonal weather in Pythagorio?
The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are January and February, with an average of 13°C. Average annual precipitation for Pythagorio is 837 mm.