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8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

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Our top choices for Odessa Regional Medical Center hotels

A modern interior with a high ceiling, exposed beams, and a central staircase. There are seating areas with tables and chairs, and a bar area with a counter.
A modern lobby with a central staircase, seating areas, and a reception desk.
A Marriott hotel with a swimming pool, lounge chairs, and potted plants.
A modern interior with a bar area, seating, and a fireplace.

1. Odessa Marriott Hotel & Conference Center

Odessa Marriott Hotel & Conference Center
0.2 km from Odessa Regional Medical Center
United States
John
฿6,123
฿7,042 total
includes taxes & fees
16 Oct - 17 Oct
Odessa Marriott Hotel & Conference Center
An outdoor patio area with stone flooring, tables, and chairs.
A modern hotel lobby with a bar area, seating, and a large screen.
A hotel room with a large bed, a desk, a chair, a TV, and a window.
A room with two desks, each with a laptop and a chair. There is a bookshelf with colorful books and a door in the background.

2. Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG
3.1 km from Odessa Regional Medical Center
United States
Corina I.
฿3,261
฿3,789 total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Express & Suites Odessa I-20 by IHG
A modern kitchen with a central island, bar stools, and a flat-screen TV mounted on the wall.
A modern lobby with a red sofa, black chairs, a coffee table, and a patterned carpet.
A MainStay Suites hotel with a modern facade, multiple floors, and a covered entrance.
A gym with cardio machines, a mirror, and a painting on the wall.

3. MainStay Suites Odessa I-20

MainStay Suites Odessa I-20
3 km from Odessa Regional Medical Center
United States
Alejandro
฿2,523
฿2,901 total
includes taxes & fees
16 Oct - 17 Oct
MainStay Suites Odessa I-20
A hotel room with a coffee machine, a trash bin, a small table with a potted plant, and a view of a staircase leading to an outdoor area.
A hotel room with two beds, a desk with chairs, a flat-screen TV mounted on the wall, and a window with curtains.
A room with a washing machine, a dryer, and a Coca-Cola refrigerator.
A modern hotel lobby with a reception desk, a coffee machine, and a staircase leading to an upper floor.

4. Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street
1.9 km from Odessa Regional Medical Center
United States
Susan
฿1,815
฿2,087 total
includes taxes & fees
9 Oct - 10 Oct
Motel 6 Odessa, TX - 2nd Street
An indoor swimming pool with a clear blue water, surrounded by a tiled deck and a black metal fence.
A reception area with a marble counter, a potted plant, and artwork on the walls.
A hotel room with two beds, a desk, a chair, a lamp, a TV, and an air conditioning unit.
A room with two red sofas, a coffee table, a TV, and large windows.

5. SureStay Plus Hotel by Best Western Odessa

SureStay Plus Hotel by Best Western Odessa
2.7 km from Odessa Regional Medical Center
United States
Laura
฿2,683
฿3,085 total
includes taxes & fees
12 Oct - 13 Oct
SureStay Plus Hotel by Best Western Odessa
A hotel room with two beds, a desk, a chair, a heater, and two framed pictures on the walls.
A living room with a sofa, a coffee table, and a vase of flowers.
A building facade with a large glass door entrance, a neon 'OPEN' sign, and a yellow curb.
A corridor with fire extinguishers on the wall, windows, and a covered walkway.

6. Villa West Inn

Villa West Inn
2.6 km from Odessa Regional Medical Center
United States
Armando
฿2,084
฿2,397 total
includes taxes & fees
20 Oct - 21 Oct
Villa West Inn
A motel with a covered parking area, multiple rooms, and a small commercial space.
A corridor with a brick wall, a covered walkway, and a view of parked cars.
A hotel room with two beds, a desk, a television, and a microwave.
A compact kitchen with a microwave, coffee maker, and a trash bin. A window offers a view of the outside.

7. Deluxe Inn By Capital O Odessa I-20

Deluxe Inn By Capital O Odessa I-20
2.5 km from Odessa Regional Medical Center
United States
Alan
฿1,849
฿2,219 total
includes taxes & fees
9 Oct - 10 Oct
Deluxe Inn By Capital O Odessa I-20
An entrance sign for the Americas Best Value Inn, featuring a blue and red color scheme with a star logo.
A neatly made bed with white linens and pillows, a folded towel, and a window with curtains.
A coffee cup with a lid and a paper bag containing a croissant on a wooden surface.
A basic earth hair care kit with shampoo, conditioner, and body lotion.

8. Americas Best Value Inn & Suites Odessa

Americas Best Value Inn & Suites Odessa
2.5 km from Odessa Regional Medical Center
฿1,850
฿1,998 total
includes taxes & fees
7 Nov - 8 Nov
Americas Best Value Inn & Suites Odessa
A hotel room with two single beds, each with a patterned bedspread and white pillows. There is a nightstand with a lamp between the beds.
A compact hotel room with a washing machine, dryer, and a vending machine.
A reception desk with a wooden counter, a computer monitor, and a plant. There are signs for human trafficking and a fire extinguisher.
A room with a coffee machine, a sign about morning charge, and a poster on the wall.

9. Motel 6 Odessa, TX

Motel 6 Odessa, TX
2.9 km from Odessa Regional Medical Center
United States
Veronica
฿1,983
฿2,281 total
includes taxes & fees
20 Oct - 21 Oct
Motel 6 Odessa, TX
A covered outdoor seating area with tables and chairs, wooden beams, and a view of the building in the background.
Lobby
Children’s play area – indoor
Room

10. MCM Grande Hotel FunDome Odessa

MCM Grande Hotel FunDome Odessa
6.4 km from Odessa Regional Medical Center
United States
Justin
฿2,425
฿2,789 total
includes taxes & fees
18 Oct - 19 Oct
MCM Grande Hotel FunDome Odessa
A modern living room with a sectional sofa, a fireplace, and a mounted TV.
A gym with exercise equipment, a bench, and a TV on the wall.
A hotel lobby with a reception desk, seating area, and a television mounted on the wall.
A hotel room with a large bed, two bedside lamps, a nightstand, and a patterned carpet.

11. Baymont by Wyndham Odessa

Baymont by Wyndham Odessa
9.2 km from Odessa Regional Medical Center
United States
Suzanne
฿2,089
฿2,403 total
includes taxes & fees
11 Oct - 12 Oct
Baymont by Wyndham Odessa
A hotel room with a large sliding glass door leading to a balcony, a bed with a blue and white patterned rug, a small table with a potted plant, and a brick wall.
A lobby with a large aquarium, red and green seating, and a red carpeted floor.
A hot tub with a brick surround, a swimming pool, lounge chairs, and umbrellas.
A modern hotel room with a large bed, a desk, a chair, and a view of the outdoors.

12. MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa
6 km from Odessa Regional Medical Center
United States
Rosalind
฿3,435
฿3,950 total
includes taxes & fees
16 Oct - 17 Oct
MCM Elegante Hotel and Conference Center Odessa
A spacious living area with a sofa, chairs, and a coffee table. There is a kitchen area with a counter and appliances in the background.
A reception area with a counter, two pendant lights, a decorative wall, and a floor with a patterned rug.
A hotel room with a bed, a sofa, a desk with a chair, a TV, and a lamp.
A hotel lobby with multiple seating areas, a coffee station, and a reception desk.

13. Best Western Plus North Odessa Inn & Suites

Best Western Plus North Odessa Inn & Suites
8.6 km from Odessa Regional Medical Center
United States
Aravindakrishna
฿2,931
฿3,371 total
includes taxes & fees
16 Oct - 17 Oct
Best Western Plus North Odessa Inn & Suites
A walk-in shower with a glass door, a handrail, a grab bar, a white towel, and a framed picture on the wall.
A Courtyard Marriott hotel with a stone facade, multiple windows, and a flagpole.
A hotel lobby with a bar area, seating, and a digital screen displaying news.
A hotel lobby with a reception desk, seating area, and artwork on the walls.

14. Courtyard Odessa

Courtyard Odessa
8.6 km from Odessa Regional Medical Center
United States
alan
฿3,546
฿4,150 total
includes taxes & fees
16 Oct - 17 Oct
Courtyard Odessa
An outdoor seating area with colorful striped sofas and chairs, a central fire feature, and a covered patio with wooden ceiling and glass doors.
A hotel reception area with a modern design, featuring a reception desk, a digital kiosk, a minibar, and a self-service beverage station.
A hotel room with a sofa, a bedside table with a lamp, a bed, and a wall-mounted telephone.
A modern hotel with a covered entrance, a fire lane, and a landscaped area with shrubs.

15. Home2 Suites by Hilton Odessa

Home2 Suites by Hilton Odessa
8.3 km from Odessa Regional Medical Center
United States
Emilio
฿3,975
฿4,571 total
includes taxes & fees
7 Nov - 8 Nov
Home2 Suites by Hilton Odessa
A hotel room with a bed, a desk, a blue sofa, a TV, and a wardrobe.
A modern kitchen area with a self-serve station featuring cereal, waffles, and a waffle maker.
A La Quinta hotel with a modern design, featuring a prominent entrance and multiple parking spaces.
A well-lit snack bar with refrigerated beverage dispensers and shelves stocked with various snacks and packaged goods.

16. La Quinta Inn & Suites by Wyndham Odessa N. - Sienna Tower

La Quinta Inn & Suites by Wyndham Odessa N. - Sienna Tower
10.3 km from Odessa Regional Medical Center
United States
Brandon
฿3,331
฿3,830 total
includes taxes & fees
8 Nov - 9 Nov
La Quinta Inn & Suites by Wyndham Odessa N. - Sienna Tower
A modern dining area with a long table and chairs, a coffee station, and a large window providing a view of the outdoors.
A modern interior with a market area, seating, and a counter.
A modern reception area with a counter, a 'Market' sign, and a refrigerated display case with beverages.
A modern hotel lobby with a reception desk, seating area, and a kitchen in the background.

17. avid hotel Odessa Northwest by IHG

avid hotel Odessa Northwest by IHG
11.2 km from Odessa Regional Medical Center
United States
Cecilia
฿2,927
฿3,337 total
includes taxes & fees
6 Nov - 7 Nov
avid hotel Odessa Northwest by IHG
A hotel pool with lounge chairs and a sign warning against diving.
A hotel lobby with a sofa, two bar stools, a fireplace, a television, and a coffee station.
A compact hotel room with a kitchenette, a flat-screen TV, a sofa, and a dining area.
A hotel kitchen with a buffet counter, wooden cabinets, and various kitchen appliances.

18. Homewood Suites by Hilton Odessa

Homewood Suites by Hilton Odessa
8.6 km from Odessa Regional Medical Center
United States
Melisa
฿3,432
฿3,976 total
includes taxes & fees
7 Nov - 8 Nov
Homewood Suites by Hilton Odessa
A hotel entrance with a covered walkway, multiple windows, and a brick facade.
A hotel room with a bed, a desk with a computer, a chair, a TV, a coffee maker, and a microwave.
A swimming pool with lounge chairs and a sign indicating no lifeguard on duty.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

19. Holiday Inn Odessa by IHG

Holiday Inn Odessa by IHG
6.4 km from Odessa Regional Medical Center
United Kingdom
Julian
฿2,759
฿3,214 total
includes taxes & fees
7 Nov - 8 Nov
Holiday Inn Odessa by IHG
A covered outdoor seating area with stone walls and a view of the pool.
A bar area with shelves of liquor bottles, a television displaying a sports event, a cash register, and a refrigerator stocked with beverages.
An outdoor patio with a barbecue grill, pool, and dining area.
A hotel room with a bed, a sofa, a desk, a chair, a TV, and a framed picture on the wall.

20. Hawthorn Extended Stay by Wyndham Odessa

Hawthorn Extended Stay by Wyndham Odessa
4.7 km from Odessa Regional Medical Center
United States
Chris
฿2,998
฿3,448 total
includes taxes & fees
9 Oct - 10 Oct
Hawthorn Extended Stay by Wyndham Odessa
View all properties

Compare popular hotels close to Odessa Regional Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern interior with a high ceiling, exposed beams, and a central staircase. There are seating areas with tables and chairs, and a bar area with a counter.
Odessa Marriott Hotel & Conference Center
9.2
Wonderful
554 reviews
View
An outdoor patio area with stone flooring, tables, and chairs.
Holiday Inn Express & Suites Odessa I-20 by IHG
8.8
Excellent
563 reviews
View
A modern kitchen with a central island, bar stools, and a flat-screen TV mounted on the wall.
MainStay Suites Odessa I-20
8.2
Very good
343 reviews
View
A hotel room with a coffee machine, a trash bin, a small table with a potted plant, and a view of a staircase leading to an outdoor area.
Motel 6 Odessa, TX - 2nd Street
7.8
Good
569 reviews
View
An indoor swimming pool with a clear blue water, surrounded by a tiled deck and a black metal fence.
SureStay Plus Hotel by Best Western Odessa
7.6
Good
103 reviews
View

Top Odessa Regional Medical Center Hotel Reviews

Staybridge Suites Odessa - Interstate HWY 20 by IHG

Staybridge Suites Odessa - Interstate HWY 20 by IHG

10/10 Excellent
"Very nice place"
rosa 1-night trip
Posted less than an hour ago
Staybridge Suites Odessa - Interstate HWY 20 by IHG
MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa

10/10 Excellent
"N/a"
Russell 4-night trip
Posted 1 hour ago
MCM Elegante Hotel and Conference Center Odessa
Odessa Marriott Hotel & Conference Center

Odessa Marriott Hotel & Conference Center

10/10 Excellent
"Amazing suite! I wish we could have opened the balcony doors - the view was great. Very impressive property."
James 1-night trip
Posted 2 days ago
Odessa Marriott Hotel & Conference Center
Extended Stay America Select Suites - Odessa

Extended Stay America Select Suites - Odessa

10/10 Excellent
"Great stop for my fiancee and I. Quiet and well lit. Felt safe the whole time"
Vanessa 1-night trip
Posted 7 days ago
Extended Stay America Select Suites - Odessa
Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street

10/10 Excellent
"This motel was the fastest check in ever. Clean comfortable and quiet. Would totally recommend"
Susan 1-night trip
Posted 2 months ago
Motel 6 Odessa, TX - 2nd Street

Frequently asked questions

What's the area like around Odessa Regional Medical Center?
Odessa Regional Medical Center is located in Odessa. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 9 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Odessa Regional Medical Center?
Adjacent to Odessa Regional Medical Center, Odessa Marriott Hotel & Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a few miles include MCM Grande Hotel FunDome Odessa and Motel 6 Odessa, TX - 2nd Street.
How many hotels can I expect to find near Odessa Regional Medical Center?
Expedia has 9 hotels and other accommodation options within a mile from Odessa Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Odessa Regional Medical Center, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best deals near Odessa Regional Medical Center.
What can I see and do near Odessa Regional Medical Center?
Study the collections at White-Pool House, Ellen Noel Art Museum or Parker House Museum. Create some family memories at Altitude Trampoline Park and Fun City. Attractions like Globe of the Great Southwest and Presidential Museum and Leadership Library highlight the local culture.