A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

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Check availability on Mytilene Spa Hotels

Tonight
27 Aug - 28 Aug
Tomorrow
28 Aug - 29 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sep - 6 Sep

Our top choices for Mytilene hotels with a spa

Steam room
Family Room, Annex Building
Front of property – evening/night
Property entrance

1. Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
  • Escape to a boutique spa retreat with hot springs and massage therapy in the heart of Mytilene.
฿5,287
฿6,174 total
includes taxes & fees
20 Sept - 21 Sept
Theofilos Paradise Boutique Hotel
Massage
Exterior
Grand Suite
Exterior

2. Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
  • Relax in a coastal spa haven with hydrotherapy, hot springs, and three indoor pools for ultimate rejuvenation.
฿4,584
฿5,594 total
includes taxes & fees
2 Sept - 3 Sept
Mythical Coast Wellness Retreat
Terrace/patio
Terrace/patio
Front of property
Executive Room, Sea View | Terrace/patio

3. Elysion Hotel

Elysion Hotel
Lesvos
  • Immerse in a rejuvenating Greek island escape with tennis courts, seasonal pools, and serene balconied rooms overlooking Lesvos.
฿5,189
฿7,213 total
includes taxes & fees
26 Sept - 27 Sept
Elysion Hotel
Exterior
Exterior
Pool
Exterior

4. Elies Residences

Elies Residences
Lesvos
  • Relax in premium villas with spa treatments and outdoor pool in this serene getaway.
฿5,644
฿6,260 total
includes taxes & fees
22 Sept - 23 Sept
Elies Residences
Deluxe Double Room, Balcony | Terrace/patio
Bathroom
View from room
Deluxe Double Room, Balcony | Terrace/patio

5. Olive Green Studios and Apartments

Olive Green Studios and Apartments
Lesvos
  • Rejuvenating seaside retreat offers in-room massages and a tranquil garden sanctuary, perfect for a wellness escape by the beach.
฿5,153
฿5,721 total
includes taxes & fees
3 Sept - 4 Sept
Olive Green Studios and Apartments
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Choose what matters most at spa hotels in Mytilene

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Mytilene Hotel Reviews

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

8/10 Good
"Staff was nice. Large breakfast spread. Location is great."
Caroline 1-night trip
Posted 2 weeks ago
Theofilos Paradise Boutique Hotel

Frequently asked questions

Looking to holiday at a spa hotel in Mytilene?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Discover the museums and churches in Mytilene—your cultural tour starts here. Enjoy the architecture and sea views during your holiday. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Mytilene?
Mythical Coast Wellness Retreat is a top beach spa hotel featuring 5 restaurants, 5 bars, 3 indoor pools and 5 cafes. Treat yourself to a facial, body scrub or Swedish massage at Mythical Coast Spa. Another popular spa hotel in Mytilene is Theofilos Paradise Boutique Hotel.
How many spa hotels are there in Mytilene?
Among Expedia's 88 accommodation options in Mytilene, there are 2 spa hotels.
What's there to see and do in Mytilene?
When you're in Mytilene, enjoy exploring the sights and attractions here including Port of Mytilene, Mytilini Castle and Olive-press Museum of Archipelagos Society. If you have a bit of extra time while you're in the area, you might want to check out Roman Aqueduct at Moria and Thermes Gera Hot Springs.
What is a Mytilene spa hotel?
Spa hotels in Mytilene feature full on-site spas offering services including couples massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your holiday.