Default HTG hotel image

Search Hotels in Medical Center, Detroit

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Medical Center hotels

A modern bar area with a curved ceiling, a bar counter, and seating.

1. AC Hotel by Marriott Detroit at the Bonstelle

AC Hotel by Marriott Detroit at the Bonstelle
2.0 star property
Brush Park, 0.9 km from Medical Center
9.4 out of 10, Exceptional, (307 reviews)
"Great stay"
United States
Zerina
The price is ฿7,572
฿8,481 total
includes taxes & fees
8 Nov - 9 Nov
AC Hotel by Marriott Detroit at the Bonstelle
A modern bathroom with a walk-in shower, a freestanding bathtub, and a built-in towel rack.

2. MotorCity Casino Hotel

MotorCity Casino Hotel
4.5 star property
North Corktown, 2 km from Medical Center
8.8 out of 10, Excellent, (4,877 reviews)
"Great stay, looking forward to coming back!"
United States
Jack
The price is ฿5,990
฿6,889 total
includes taxes & fees
2 Nov - 3 Nov
MotorCity Casino Hotel
A bar area with multiple seating arrangements and a counter with a variety of bottles and glasses.

3. MGM Grand Detroit

MGM Grand Detroit
4.5 star property
Downtown Detroit, 2.4 km from Medical Center
8.6 out of 10, Excellent, (1,060 reviews)
"The rooms were wonderful and we had a great time at the casino"
United States
Brenda
The price is ฿6,710
฿8,647 total
includes taxes & fees
15 Nov - 16 Nov
MGM Grand Detroit
A hotel room with a large bed, a desk, a chair, and a view of the cityscape.

4. Hollywood Casino at Greektown

Hollywood Casino at Greektown
4.0 star property
Greektown Historic District, 2.4 km from Medical Center
8.6 out of 10, Excellent, (5,790 reviews)
"Friendly staff, nice accommodations."
United States
Chase
The price is ฿4,721
฿6,367 total
includes taxes & fees
23 Nov - 24 Nov
Hollywood Casino at Greektown
A spacious lobby with a central seating area, multiple dining tables, and a grand piano.

5. Atheneum Suite Hotel

Atheneum Suite Hotel
4.0 star property
Greektown Historic District, 2.5 km from Medical Center
9.2 out of 10, Wonderful, (2,560 reviews)
"The location is great and staff were very friendly"
United States
Nichole
The price is ฿5,311
฿6,108 total
includes taxes & fees
23 Nov - 24 Nov
Atheneum Suite Hotel
A lobby with a chandelier, a reception desk, a sofa, and a table with flowers.

6. The Siren Hotel, an Ash Hotel

The Siren Hotel, an Ash Hotel
4.0 star property
Downtown Detroit, 2.2 km from Medical Center
9.0 out of 10, Wonderful, (2,170 reviews)
"Great stay"
United States
Lankatilaka
The price is ฿4,674
฿5,234 total
includes taxes & fees
23 Nov - 24 Nov
The Siren Hotel, an Ash Hotel
A modern hotel lobby with a high ceiling, large windows offering city views, a central seating area, and a staircase leading to an upper level.

7. Fort Pontchartrain Detroit, a Wyndham Hotel

Fort Pontchartrain Detroit, a Wyndham Hotel
3.5 star property
Downtown Detroit, 3.1 km from Medical Center
8.8 out of 10, Excellent, (2,285 reviews)
"Great location and friendly staff!"
United States
Sarima
The price is ฿4,557
฿5,241 total
includes taxes & fees
29 Nov - 30 Nov
Fort Pontchartrain Detroit, a Wyndham Hotel
A spacious lobby with a high ceiling, large potted plants, and a bar area with shelves of bottles.

8. Cambria Hotel Detroit Downtown

Cambria Hotel Detroit Downtown
4.0 star property
Downtown Detroit, 2.8 km from Medical Center
9.4 out of 10, Exceptional, (1,423 reviews)
"Always great place to stay"
United States
Raysheen
The price is ฿5,444
฿6,287 total
includes taxes & fees
8 Nov - 9 Nov
Cambria Hotel Detroit Downtown
A Hilton Garden Inn hotel with a prominent sign, multiple floors, and a corner entrance.

9. Hilton Garden Inn Detroit Downtown

Hilton Garden Inn Detroit Downtown
3.0 star property
Downtown Detroit, 2.2 km from Medical Center
8.6 out of 10, Excellent, (1,006 reviews)
"The location was great. Staff members were very welcoming and helpful."
United States
Amanda
The price is ฿5,791
฿6,660 total
includes taxes & fees
8 Nov - 9 Nov
Hilton Garden Inn Detroit Downtown
An outdoor patio area with seating and a glass-enclosed restaurant.

10. Holiday Inn Express & Suites Detroit Dearborn by IHG

Holiday Inn Express & Suites Detroit Dearborn by IHG
2.5 star property
13.3 km from Medical Center
8.6 out of 10, Excellent, (1,003 reviews)
"Very clean and very large rooms and breakfast was very good"
United States
Adina
The price is ฿3,717
฿4,107 total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Detroit Dearborn by IHG
A rooftop restaurant with a city view, modern design, and outdoor seating.

11. The Godfrey Detroit, Curio Collection By Hilton

The Godfrey Detroit, Curio Collection By Hilton
4.0 star property
Corktown, 2.8 km from Medical Center
9.2 out of 10, Wonderful, (2,097 reviews)
"Nice, clean and friendly atmosphere"
United States
Tony
The price is ฿4,674
฿5,375 total
includes taxes & fees
23 Nov - 24 Nov
The Godfrey Detroit, Curio Collection By Hilton
A reception desk with a framed picture, a potted plant, a glass vase with flowers, a small plant, and a decorative plate.

12. Comfort Inn Detroit Downtown

Comfort Inn Detroit Downtown
2.5 star property
Elmwood Park, 3.1 km from Medical Center
7.2 out of 10, Good, (1,007 reviews)
"The breakfast was amazing!!Great for a hotel breakfast!"
United States
Brette
The price is ฿2,738
฿3,020 total
includes taxes & fees
24 Nov - 25 Nov
Comfort Inn Detroit Downtown
A modern bar area with a variety of seating options, including bar stools and cushioned chairs, and a large bar counter with a well-stocked selection of bottles.

13. Detroit Foundation Hotel

Detroit Foundation Hotel
4.0 star property
Downtown Detroit, 3 km from Medical Center
9.4 out of 10, Exceptional, (1,000 reviews)
"Great stay!"
United States
Kimberly
The price is ฿7,557
฿8,733 total
includes taxes & fees
29 Nov - 30 Nov
Detroit Foundation Hotel
A hotel entrance with a sign reading 'HOTEL INDIGO,' large windows, and potted plants at the entrance.

14. Hotel Indigo Detroit Downtown by IHG

Hotel Indigo Detroit Downtown by IHG
3.5 star property
Downtown Detroit, 2.6 km from Medical Center
8.4 out of 10, Very good, (1,459 reviews)
"Staff were great! Restaurant fantastic pricing and food. Would definitely stay again!"
United States
beth
The price is ฿5,227
฿6,086 total
includes taxes & fees
29 Nov - 30 Nov
Hotel Indigo Detroit Downtown by IHG
A bar area with a long counter, stools, and a bar stocked with bottles. There are large windows and a view of the outside.

15. ROOST Detroit

ROOST Detroit
4.5 star property
Downtown Detroit, 2.4 km from Medical Center
9.8 out of 10, Exceptional, (1,006 reviews)
"Great hotel. Very clean and comfortable and staff were great"
Canada
David
The price is ฿7,268
฿9,286 total
includes taxes & fees
8 Nov - 9 Nov
ROOST Detroit
A stone building with a large wooden door and a pointed roof.

16. The Inn on Ferry Street

The Inn on Ferry Street
3.5 star property
Cultural Center, 1.2 km from Medical Center
8.6 out of 10, Excellent, (268 reviews)
"Amazing place"
United States
Keith
The price is ฿4,855
฿6,050 total
includes taxes & fees
15 Nov - 16 Nov
The Inn on Ferry Street
A spacious restaurant with long wooden tables, multiple seating arrangements, and a modern industrial ceiling design.

17. Trumbull and Porter Hotel

Trumbull and Porter Hotel
3.5 star property
Corktown, 3.2 km from Medical Center
8.4 out of 10, Very good, (1,446 reviews)
"Very nice hotel I would definitely stay again"
United States
Raymond
The price is ฿4,227
฿4,735 total
includes taxes & fees
15 Nov - 16 Nov
Trumbull and Porter Hotel
A formal dining room with wooden flooring, dark upholstered chairs, and a chandelier.

18. The Detroit Club

The Detroit Club
4.0 star property
Downtown Detroit, 2.8 km from Medical Center
9.2 out of 10, Wonderful, (588 reviews)
"Really enjoyed our stay here."
United States
Leah
The price is ฿5,204
฿6,802 total
includes taxes & fees
9 Nov - 10 Nov
The Detroit Club
A multi-story hotel with a sign reading "Hyatt Place" and "Regis" above it.

19. Hyatt Place Detroit Royal Oak

Hyatt Place Detroit Royal Oak
3.0 star property
17 km from Medical Center
9.6 out of 10, Exceptional, (1,002 reviews)
"Excellent stay"
United States
Arleth
The price is ฿5,643
฿6,235 total
includes taxes & fees
8 Nov - 9 Nov
Hyatt Place Detroit Royal Oak
An indoor seating area with tables and chairs, large windows with a view of a construction site, and hanging pendant lights.

20. Holiday Inn Express & Suites Allen Park by IHG

Holiday Inn Express & Suites Allen Park by IHG
2.5 star property
16.5 km from Medical Center
8.8 out of 10, Excellent, (1,171 reviews)
"Great location, staff and room."
United States
Robin
The price is ฿3,675
฿4,061 total
includes taxes & fees
29 Nov - 30 Nov
Holiday Inn Express & Suites Allen Park by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern bar area with a curved ceiling, a bar counter, and seating.
AC Hotel by Marriott Detroit at the Bonstelle
2.0 star property
9.4
Exceptional
307 reviews
View
A lobby with a chandelier, a reception desk, a sofa, and a table with flowers.
The Siren Hotel, an Ash Hotel
4.0 star property
9.0
Wonderful
2,170 reviews
View
A rooftop restaurant with a city view, modern design, and outdoor seating.
The Godfrey Detroit, Curio Collection By Hilton
4.0 star property
9.2
Wonderful
2,097 reviews
View
A spacious lobby with a central seating area, multiple dining tables, and a grand piano.
Atheneum Suite Hotel
4.0 star property
9.2
Wonderful
2,560 reviews
View
A stone building with a large wooden door and a pointed roof.
The Inn on Ferry Street
3.5 star property
8.6
Excellent
268 reviews
View

Where to stay in Medical Center

Find the best Medical Center areas for the activities you enjoy most.
A cityscape with tall buildings, a large circular sculpture, and an American flag.

Downtown Detroit

Detroit is known for its architecture, industrialization and the arts. As creative entrepreneurs reclaim downtown, a new urban culture is rising next to the old.

A directional sign with arrows pointing to Paint Creek Trail and Clinton River Trail.

Rochester Hills

Live music, restaurants and shopping are some highlights of Rochester Hills. Make a stop by The Village Of Rochester Hills or Meadow Brook Amphitheatre while you're exploring.

A cityscape with tall buildings, a statue, and autumn trees.

Midtown

If you're spending time in Midtown, check out sights like Little Caesars Arena or The Majestic Theatre and hop on the metro to see more of the city at Canfield Street Station or Martin Luther King Boulevard/Mack Avenue Station.

A tall, historic building with many windows and a classical architectural style.

Corktown

You'll enjoy the live music and historical sites in Corktown. You might want to make time for a stop at Michigan Central or PJ's Lager House.

A church with a tall spire and arched windows.
Photo by Terry Fletcher
Open Photo by Terry Fletcher

Brush Park

Brush Park might not have many top sights, but Little Caesars Arena and Ford Field are two attractions nearby that you can check out.

Top Medical Center Hotel Reviews

Trumbull and Porter Hotel

Trumbull and Porter Hotel

8/10 Good
"Bar was great, staff was great. Room was clean but missing towels"
Colleen 1-night trip
Posted 7 hours ago
Trumbull and Porter Hotel

Frequently asked questions

What's it like in Medical Center?
Travellers to the Medical Center neighbourhood in Detroit will be sure to enjoy their stay. Make sure that you visit Cultural Center Historic District and Lexus Velodrome as part of your Medical Center travel plans.
If I need to cancel my hotel reservation in Medical Center, will I receive a refund?
Yes, most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Medical Center.
What is there to do in this Detroit neighbourhood?
A few attractions you might want to check out while you're in Medical Center are Cultural Center Historic District and Lexus Velodrome. Little Caesars Arena and Ford Field are also worth a visit when you're out sightseeing in Detroit.