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Check prices for these dates

Tonight
4 Mar - 5 Mar
Tomorrow
5 Mar - 6 Mar
This weekend
6 Mar - 8 Mar
Next weekend
13 Mar - 15 Mar

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Our top choices for Medi Center hotels

Free daily continental breakfast

Quality Inn San Diego I-5 Naval Base

Quality Inn San Diego I-5 Naval Base
2.5 star property
3.2 km from Medi Center
7.8 out of 10, Good, (901 reviews)
"It's great place, clean, friendly staff. Especially Laura, she is very accommodating. All was very good👍"
United States
Gilbert
The price is ฿3,171
฿3,582 total
includes taxes & fees
8 Mar - 9 Mar
Quality Inn San Diego I-5 Naval Base
Reception

Lodge at 32nd

Lodge at 32nd
2.5 star property
1.8 km from Medi Center
7.6 out of 10, Good, (808 reviews)
"Great price and location"
United States
Courtney
The price is ฿3,119
฿3,870 total
includes taxes & fees
5 Mar - 6 Mar
Lodge at 32nd
Reception

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 4.2 km from Medi Center
9.6 out of 10, Exceptional, (813 reviews)
"The room was clean!"
United States
Jiho
Stay Classy Hostel
Premium bedding, in-room safe, desk, laptop workspace

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
5.7 km from Medi Center
9.2 out of 10, Wonderful, (3,751 reviews)
"My favorite place to stay"
United States
Rubidia
The price is ฿4,019
฿4,429 total
includes taxes & fees
8 Mar - 9 Mar
Best Western Plus Marina Gateway Hotel
Poolside bar

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 5 km from Medi Center
9.0 out of 10, Wonderful, (3,370 reviews)
"Great place to stay!"
United States
CINDY
The price is ฿7,280
฿9,950 total
includes taxes & fees
11 Mar - 12 Mar
Hard Rock Hotel San Diego
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
5.5 km from Medi Center
9.0 out of 10, Wonderful, (1,152 reviews)
"Great restaurant/Bar."
United States
Maria Elena
The price is ฿4,640
฿5,380 total
includes taxes & fees
9 Mar - 10 Mar
The DEXTRO Little Italy, BW Premier Collection
Lobby sitting area

Holiday Inn Express San Diego South - National City by IHG

Holiday Inn Express San Diego South - National City by IHG
2.5 star property
4.2 km from Medi Center
8.4 out of 10, Very good, (1,004 reviews)
"Clean rooms, great breakfast!"
United States
Ramiro
The price is ฿4,264
฿4,698 total
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express San Diego South - National City by IHG
Rooftop terrace

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
East Village, 4.6 km from Medi Center
9.4 out of 10, Exceptional, (735 reviews)
"Great place to stay "
United States
KELLY
The price is ฿4,770
฿6,439 total
includes taxes & fees
12 Mar - 13 Mar
Sentral Gaslamp Quarter
Blackout curtains, iron/ironing board, free cots/infant beds, free WiFi

Howard Johnson by Wyndham National City/San Diego South

Howard Johnson by Wyndham National City/San Diego South
2.0 star property
3.7 km from Medi Center
7.4 out of 10, Good, (1,009 reviews)
"Very clean and quiet thank you "
United States
Rocky
The price is ฿2,310
฿2,545 total
includes taxes & fees
31 Mar - 1 Apr
Howard Johnson by Wyndham National City/San Diego South
Exterior

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
4.9 km from Medi Center
9.4 out of 10, Exceptional, (1,024 reviews)
"Great place to stay!"
Canada
Rose Marie JOy
The price is ฿5,298
฿6,143 total
includes taxes & fees
3 Apr - 4 Apr
Marriott Vacation Club®, San Diego
Dinner served

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Gaslamp Quarter, 4.9 km from Medi Center
9.2 out of 10, Wonderful, (2,066 reviews)
"Great location, clean and comfortable rooms, friendly staff."
United States
Maya
The price is ฿6,103
฿8,494 total
includes taxes & fees
4 Apr - 5 Apr
Omni San Diego Hotel at the Ballpark
Exterior

San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 4.9 km from Medi Center
8.8 out of 10, Excellent, (1,668 reviews)
"Lovely hotel and perfect location near many amenities. "
United States
Johan
The price is ฿5,076
฿5,885 total
includes taxes & fees
2 Apr - 3 Apr
San Diego Marriott Gaslamp Quarter
3 bars/lounges, lobby lounge, cocktail bar, cocktail bar

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
5.8 km from Medi Center
9.2 out of 10, Wonderful, (1,501 reviews)
"Stunning hotel, I could have stayed there all day looking at every little design detail. "
United States
Holly
The price is ฿7,179
฿8,238 total
includes taxes & fees
9 Mar - 10 Mar
Lafayette Hotel & Club
Lobby

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 5 km from Medi Center
9.0 out of 10, Wonderful, (1,029 reviews)
"Clean quiet friendly helpful staff convenient location will stay there again"
United States
David
The price is ฿3,760
฿4,277 total
includes taxes & fees
11 Mar - 12 Mar
Gaslamp Plaza Suites
Lobby lounge

Moxy San Diego Downtown/Gaslamp Quarter

Moxy San Diego Downtown/Gaslamp Quarter
3.5 star property
Gaslamp Quarter, 4.9 km from Medi Center
9.0 out of 10, Wonderful, (1,003 reviews)
"I love this hotel! Staff, hotel, and room wonderful!"
United States
Debbie
The price is ฿4,699
฿5,733 total
includes taxes & fees
3 Apr - 4 Apr
Moxy San Diego Downtown/Gaslamp Quarter
Interior

Gaslamp Hostel

Gaslamp Hostel
2.0 star property
Gaslamp Quarter, 5.1 km from Medi Center
9.2 out of 10, Wonderful, (558 reviews)
"The staff was always so nice and friendly, breakfast options were just cereals. The room and bathrooms were always clean so 10/10 "
United States
Adriana
Gaslamp Hostel
Lobby sitting area

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 4.9 km from Medi Center
9.4 out of 10, Exceptional, (1,007 reviews)
"Great location and stay. "
United States
Simran
The price is ฿4,204
฿5,781 total
includes taxes & fees
4 Apr - 5 Apr
Staypineapple, Hotel Z, Gaslamp San Diego
View from room

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 5.6 km from Medi Center
9.0 out of 10, Wonderful, (407 reviews)
"Great place to stay "
United States
Jacorey
The price is ฿4,922
฿5,707 total
includes taxes & fees
4 Apr - 5 Apr
Courtyard by Marriott San Diego Downtown Little Italy
Lobby sitting area

Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 5 km from Medi Center
8.6 out of 10, Excellent, (2,274 reviews)
"Overall great atmosphere and staff really nice!"
United States
Daniel
The price is ฿5,371
฿6,228 total
includes taxes & fees
8 Mar - 9 Mar
Palihotel San Diego Gaslamp Quarter
Lobby lounge

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
5.4 km from Medi Center
8.6 out of 10, Excellent, (1,514 reviews)
"Great stay, great location, great staff."
United States
Jodie
The price is ฿6,809
฿7,895 total
includes taxes & fees
7 Mar - 8 Mar
The Bristol Hotel San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Medi Center Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"Very clean room and courteous front desk staff. Short walk to great restaurants in Little Italy and not far from Waterfront Park. Wonderful neighborhood. We had a rental car and parking was convenient. Highly recommended!"
Lai Lai Lily 3-night trip
Posted 1 day ago
The DEXTRO Little Italy, BW Premier Collection

Hotels near other Medi Center attractions

Nu-Way Christian Ministries

Find out about the history of San Diego with a stop at Nu-Way Christian Ministries.
See properties

Pilgrim Progressive Baptist Church

Pilgrim Progressive Baptist Church is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels?
See properties

Frequently asked questions

What's the area like around Medi Center?
Medi Center is located in San Diego. If you're looking for a convenient place to stay, take a look at the 22 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Medi Center?
Hard Rock Hotel San Diego is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an outdoor pool. It's located 3.1 mi (5 km) from Medi Center. Other good choices within 5 miles include The DEXTRO Little Italy, BW Premier Collection and The Sofia Hotel.
How many hotels should I expect to find near Medi Center?
Expedia has 22 hotels and other accommodation options within a mile from Medi Center.
If I need to cancel the hotel reservation for my stay near Medi Center, will I receive a refund?
Yes, most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view top deals close to Medi Center.
What can I see and do near Medi Center?
San Diego Natural History Museum, San Diego Air and Space Museum and Maritime Museum of San Diego feature a variety of fascinating exhibits to see while you're in town. Hotel del Coronado, Casa de Balboa and Nu-Way Christian Ministries are some of the notable landmarks to see in the area. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park and Cal Coast Credit Union Open Air Theater if you're interested in local theatre.