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Check prices for these dates

This weekend
10 Jul - 12 Jul
Next weekend
17 Jul - 19 Jul

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Our top choices for Main Street Hyannis hotels

Terrace/patio

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1,004 reviews)
"Great location and very accommodating staff."
United States
Jovian
The price is ฿9,263
฿11,550 total
includes taxes & fees
8 Jul - 9 Jul
Anchor In Distinctive Waterfront Lodging
Exterior

Cape Cod Harbor House Inn

Cape Cod Harbor House Inn
2.5 star property
0.4 km from Main Street Hyannis
9.2 out of 10, Wonderful, (317 reviews)
"The room was super clean and the facility was centrally located. "
United States
Vincent
The price is ฿5,939
฿6,796 total
includes taxes & fees
7 Jul - 8 Jul
Cape Cod Harbor House Inn
Indoor pool, seasonal outdoor pool

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
4.0 star property
1.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (196 reviews)
"Great place"
United Kingdom
Ming Da
The price is ฿9,196
฿10,893 total
includes taxes & fees
12 Jul - 13 Jul
Uncommoner Hotel by Reverie Boutique Collection
View from property

Green Harbor Resort

Green Harbor Resort
3.0 star property
2.1 km from Main Street Hyannis
9.6 out of 10, Exceptional, (361 reviews)
"Wonderful resort, everything - amenities, grounds and rooms - so well taken care of."
United States
Douglas
The price is ฿13,705
฿17,411 total
includes taxes & fees
29 Jul - 30 Jul
Green Harbor Resort
Exterior

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
0.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (53 reviews)
"It is on Main St. and convenient to the beaches, restaurants, and shopping."
United States
Dennis
The price is ฿5,939
฿6,797 total
includes taxes & fees
2 Aug - 3 Aug
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Marina

Cape Cod Inn

Cape Cod Inn
2.0 star property
0.2 km from Main Street Hyannis
8.6 out of 10, Excellent, (520 reviews)
"Great stay in a nice location. We just stayed a night on the way up the Cape. It was just what we needed. Simple, clean, and good location."
United States
Jamie
The price is ฿4,545
฿5,202 total
includes taxes & fees
7 Jul - 8 Jul
Cape Cod Inn
Indoor pool

Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.6 out of 10, Excellent, (97 reviews)
"Clean room staff was good hot tub was awesome and quiet place when we went"
United States
Jake
The price is ฿7,929
฿9,075 total
includes taxes & fees
8 Jul - 9 Jul
Courtyard Resort
Indoor pool

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (503 reviews)
"The hotel was clean and neat. The service was very good. I always enjoyed stay at this property."
United States
Bruce
The price is ฿11,213
฿12,834 total
includes taxes & fees
7 Jul - 8 Jul
Courtyard By Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,002 reviews)
"We loved to stay"
United States
Evelin
The price is ฿9,304
฿10,648 total
includes taxes & fees
2 Aug - 3 Aug
Hampton Inn & Suites Cape Cod-West Yarmouth
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,536 reviews)
"Convenient to restaurants, good amenities"
United States
Denice
The price is ฿8,121
฿9,675 total
includes taxes & fees
2 Aug - 3 Aug
Bayside Resort Hotel
Lobby

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (721 reviews)
"Friendly staff, great breakfast, quiet floor"
United States
Robin
The price is ฿8,261
฿9,455 total
includes taxes & fees
7 Jul - 8 Jul
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
Free daily continental breakfast

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.2 out of 10, Very good, (1,005 reviews)
"Great place "
United States
Andrea
The price is ฿5,643
฿6,459 total
includes taxes & fees
26 Jul - 27 Jul
Comfort Inn Hyannis - Cape Cod
Exterior

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
0.9 km from Main Street Hyannis
8.4 out of 10, Very good, (923 reviews)
"Clean rooms. Comfy bed!"
United States
Rick
The price is ฿9,969
฿11,410 total
includes taxes & fees
13 Jul - 14 Jul
Doubletree by Hilton Cape Cod - Hyannis
Exterior

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,096 reviews)
"The location was very ideal nd central. Staff was helpful and the stay was affordable."
United States
Ronil
The price is ฿3,602
฿4,123 total
includes taxes & fees
9 Jul - 10 Jul
Cape Sands Inn
Indoor pool, seasonal outdoor pool, pool loungers

Americas Best Value Inn & Suites Hyannis Cape Cod

Americas Best Value Inn & Suites Hyannis Cape Cod
2.0 star property
0.5 km from Main Street Hyannis
7.8 out of 10, Good, (1,004 reviews)
"It was nice place to stay"
United States
Celvin
The price is ฿4,280
฿4,898 total
includes taxes & fees
7 Jul - 8 Jul
Americas Best Value Inn & Suites Hyannis Cape Cod
Front of property

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1,004 reviews)
"Great location and comfortable rooms!"
United States
Zhaneta
The price is ฿7,758
฿9,766 total
includes taxes & fees
9 Jul - 10 Jul
Hyannis Harbor Hotel
Reception

Hyannis Host Inn

Hyannis Host Inn
2.0 star property
1.6 km from Main Street Hyannis
7.8 out of 10, Good, (478 reviews)
"Stay was pleasant"
United States
Phyllis
The price is ฿3,981
฿4,556 total
includes taxes & fees
7 Jul - 8 Jul
Hyannis Host Inn
Exterior

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,004 reviews)
"The receptionist, is super excellent"
United States
Vivian Marie
The price is ฿7,730
฿8,847 total
includes taxes & fees
2 Aug - 3 Aug
Holiday Inn Hyannis by IHG
Beach

Sunbird Cape Cod Resort

Sunbird Cape Cod Resort
2.5 star property
2.3 km from Main Street Hyannis
7.8 out of 10, Good, (570 reviews)
"The staff and accommodations were amazing. The breakfast is amazing! We all had a fantastic stay and will definitely stay there again and recommend to others."
United States
yvette
The price is ฿4,142
฿4,740 total
includes taxes & fees
9 Jul - 10 Jul
Sunbird Cape Cod Resort
Beach

Sunbird ANNEX Resort

Sunbird ANNEX Resort
2.0 star property
2.3 km from Main Street Hyannis
7.8 out of 10, Good, (862 reviews)
"Clean room staff friendly excellent breakfast nice place to go for vacation"
United States
Alberto
The price is ฿4,484
฿5,132 total
includes taxes & fees
8 Jul - 9 Jul
Sunbird ANNEX Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Main Street Hyannis

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Terrace/patio
Anchor In Distinctive Waterfront Lodging
3.0 star property
9.4
Exceptional
1,004 reviews
View
Exterior
Cape Cod Harbor House Inn
2.5 star property
9.2
Wonderful
317 reviews
View
Indoor pool, seasonal outdoor pool
Uncommoner Hotel by Reverie Boutique Collection
4.0 star property
9.4
Exceptional
196 reviews
View
View from property
Green Harbor Resort
3.0 star property
9.6
Exceptional
361 reviews
View
Exterior
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
8.8
Excellent
53 reviews
View

Top Main Street Hyannis Hotel Reviews

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

8/10 Good
"Overall our stay was enjoyable. I didn’t realize it was part of the comfort inn or that breakfast and the pool would be in a separate building. It’s a great location and reasonable price."
Josiah 5-night trip
Posted less than an hour ago
Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Hotels near other Main Street Hyannis attractions

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
See properties

Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 196 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Hyannis Plaza Hotel and Hyannis Harbor Hotel.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 196 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Whydah Pirate Museum and Edward Gorey House feature captivating exhibits. Hyannis Harbor, Winslow Crocker House and Sandy Neck Lighthouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Barnstable Dog Park and Long Pasture Wildlife Sanctuary are peaceful spots to stop and take in some fresh air.