The Best Hotels Closest to Lester E. Cox Medical Center South in Springfield - 2026 Updated Prices

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Our top choices for Lester E. Cox Medical Center South hotels

A conference room with a granite table, cushioned chairs, a fruit bowl, framed pictures, and a flat-screen TV.

The exterior of Hampton Inn with a clear sign, a welcome sign, and a clearance height sign.

A living room with patterned armchairs, a dark sofa, a glass coffee table, and framed artwork on the walls.

A business center with two computers, a printer, and a lamp. There are signs indicating the business center is available 24 hours and providing emergency and front desk contact information.

1. Hampton Inn Springfield-South

Galloway Village, 2 km from Lester E. Cox Medical Center South

Ashley

฿3,425

฿3,887 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with red seating, a fire feature, and tables and chairs.

A modern hotel lobby with a bar, seating area, kitchen, and a TV.

A modern hotel with a dark facade, multiple windows, and an American flag.

A modern hotel room with a large bed, a desk with a chair, a mirror, and a painting on the wall.

2. Homewood Suites by Hilton Springfield Medical District

Southside, 1.4 km from Lester E. Cox Medical Center South

Aaron

฿4,799

฿5,448 total

includes taxes & fees

31 Oct - 1 Nov

A hotel room with a blue sofa, two single beds, a nightstand, a lamp, and a framed picture on the wall.

A hotel dining area with a buffet, seating arrangements, and a kitchen counter.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A Holiday Inn Express & Suites hotel with a parking lot, a covered entrance, and a view of the surrounding area.

3. Holiday Inn Express and Suites Springfield Medical District by IHG

1.6 km from Lester E. Cox Medical Center South

Gwen

฿4,513

฿5,123 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a desk, a chair, a TV, and a bathroom with a sink and mirror.

A multi-story hotel with a prominent "Candlewood Suites" sign, a parking lot, and a landscaped entrance area.

A modern kitchen with a stainless steel microwave, a coffee maker, and a refrigerator.

A modern hotel room with a sofa, armchair, and a dining area with a kitchen in the background.

4. Candlewood Suites Springfield-Medical District

0.9 km from Lester E. Cox Medical Center South

Richard

฿3,974

฿4,511 total

includes taxes & fees

1 Nov - 2 Nov

A spacious living area with large windows, a bar, and modern furniture.

A modern hotel building with a prominent 'element by Westin' sign, multiple floors, and a covered entrance area.

A modern kitchen with a bar area, featuring a large TV, wooden shelves, and bar stools.

A spacious kitchen with a large island, ample seating, and a view of the cityscape through large windows.

5. Element by Marriott Springfield South

Meador Park, 1.5 km from Lester E. Cox Medical Center South

Nathaniel

฿4,682

฿5,314 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with wicker furniture, a central fire pit, and large windows.

An indoor swimming pool with clear water, surrounded by a tiled floor and a glass wall.

A hotel with a stone facade, large windows, and a clear blue sky.

A spacious hotel lobby with high ceilings, large windows, and a central seating area with tables and chairs.

6. Hilton Garden Inn Springfield, MO

Lake Springfield, 2.7 km from Lester E. Cox Medical Center South

daryl

฿4,060

฿4,651 total

includes taxes & fees

31 Oct - 1 Nov

A spacious lounge area with comfortable seating, a fireplace, and artwork on the walls.

A hotel room with a desk, chair, TV, fireplace, bed, and a small dining area.

A modern kitchen with a central island, bar stools, a dining table, and a bar area.

An outdoor patio with wicker furniture, a round table, and a grill area.

7. Residence Inn by Marriott Springfield

Southside, 0.8 km from Lester E. Cox Medical Center South

Jacob

฿3,979

฿4,517 total

includes taxes & fees

19 Oct - 20 Oct

A hotel room with two beds, a desk with a computer, a TV, and a coffee maker.

A hotel reception area with a counter displaying various alcohol bottles, a menu board, and artwork on the walls.

A hotel dining area with multiple tables and chairs, a kitchen counter with coffee machines, and a wall-mounted clock.

An indoor swimming pool with a tiled floor, a pool ladder, and a glass door leading to another room.

8. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland, 2.8 km from Lester E. Cox Medical Center South

Denise

฿2,991

฿3,457 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a flat-screen TV, a fireplace, a sofa, and a dining area with a kitchen counter.

A spacious living area with a sofa, a ceiling fan, a staircase, and a kitchen area.

A compact kitchen with a microwave, toaster, and refrigerator.

A modern living room with a fireplace, a sofa, a TV, and a staircase leading to a bedroom.

9. MainStay Suites Springfield South - Battlefield Rd

Bradford Park, 1.7 km from Lester E. Cox Medical Center South

Arthur

฿2,995

฿3,400 total

includes taxes & fees

15 Oct - 16 Oct

An indoor swimming pool with a glass ceiling, surrounded by lounge chairs and a view of the outdoors.

A modern restaurant with a stone backsplash, wooden cabinets, and a herringbone floor pattern.

A hotel room with a large bed, a wooden nightstand with a phone, two wall-mounted lamps, and a window with curtains.

A Comfort Inn hotel with a modern facade, a covered entrance, and a parking lot.

10. Comfort Inn South - Springfield

Galloway Village, 2.3 km from Lester E. Cox Medical Center South

Roger

฿3,439

฿3,903 total

includes taxes & fees

2 Nov - 3 Nov

A modern hotel lobby with a leather sofa, green chairs, a black coffee table, and a kitchen area with a green countertop.

A hotel with a prominent sign, a covered parking area, and a well-lit entrance.

A swimming pool with a lifeguard tower, surrounded by a fence and seating area.

A spacious indoor dining area with multiple round tables and chairs, large windows, and a modern staircase.

11. The Bradford Hotel, an Ascend Collection Hotel

Bradford Park, 0.5 km from Lester E. Cox Medical Center South

William

฿3,142

฿3,566 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a reception desk, a staircase, and a seating area.

A swimming pool with a hot tub, tiled floor, and a few lounge chairs.

A kitchen with a wooden table and chairs, a coffee machine, a fruit juicer, and a refrigerator.

A modern hotel lobby with a sofa, armchairs, a coffee table, and a staircase.

12. Sleep Inn Springfield South I60 near Medical District

1.8 km from Lester E. Cox Medical Center South

Dina

฿2,862

฿3,249 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a large bed, a chair, a nightstand, a lamp, and a door.

A hotel reception area with a reception desk, a framed artwork, and an exit sign.

A compact kitchenette with white cabinets, a sink, a microwave, and a refrigerator.

A hotel with a prominent sign for 'extended stay America' and a parking lot with several cars.

13. Extended Stay America Select Suites Springfield South

Southside, 0.9 km from Lester E. Cox Medical Center South

Crystal

฿2,425

฿2,752 total

includes taxes & fees

30 Oct - 31 Oct

A hotel room with a bed, bedside table, lamp, and a painting of a sunset.

A lobby with a mural, seating area, and a refrigerator labeled 'NOURISH' and 'RECHARGE'.

A modern dining area with blue chairs and white tables, a flat-screen TV mounted on the wall, and a wooden cabinet with items on it.

14. Clarion Pointe Springfield Southeast

Galloway Village, 4.8 km from Lester E. Cox Medical Center South

Amanda

฿2,668

฿3,029 total

includes taxes & fees

29 Oct - 30 Oct

A spacious indoor dining area with multiple tables and chairs, a kitchen area, and large windows allowing natural light.

A spa area with a hot tub, a pool, and a seating area with tables and chairs.

A Drury Inn & Suites hotel with a modern design, featuring a prominent entrance and stone pillars.

A modern lobby with a reception desk, seating area, and a high ceiling with recessed lighting.

15. Drury Inn & Suites Springfield, MO

11.2 km from Lester E. Cox Medical Center South

Deanna

฿3,637

฿4,165 total

includes taxes & fees

25 Oct - 26 Oct

A cozy living room with a stone fireplace, comfortable seating, and a large mirror reflecting the room.

A hotel room with a bed, bedside lamps, a desk with a sink, and a framed picture on the wall.

A hotel with a clear entrance, a covered waiting area, and a parking lot.

An indoor swimming pool with a clear water line, surrounded by lounge chairs and tables.

16. Hampton Inn Springfield-Southeast

Galloway Village, 4.9 km from Lester E. Cox Medical Center South

Donna Sue

฿4,005

฿4,546 total

includes taxes & fees

15 Oct - 16 Oct

A modern hotel room with a kitchenette, a flat-screen TV, a bed, and a large window.

An outdoor patio area with a stone wall, wooden pergola, and seating arrangements including a sofa and chairs.

A modern kitchen with wooden cabinets, a countertop with various kitchen items, and a wall-mounted shelf with decorative objects.

A modern hotel room with a dark grey sofa, a wooden side table, a desk with a chair, and two abstract paintings on the walls.

17. SpringHill Suites by Marriott Springfield North

Parkwood, 11.6 km from Lester E. Cox Medical Center South

Amanda

฿3,832

฿4,503 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a wooden headboard, bedside tables with lamps, and a small nightstand.

A Holiday Inn Express & Suites hotel with a parking lot and multiple vehicles.

A conference room with rows of tables and chairs, a flat-screen TV on the wall, and a door in the background.

A gym with treadmills, weight machines, and exercise mats.

18. Holiday Inn Express & Suites Springfield North by IHG

11.8 km from Lester E. Cox Medical Center South

Jerry

฿3,832

฿4,350 total

includes taxes & fees

25 Oct - 26 Oct

A spacious living area with a large island table, comfortable seating, and a view of an outdoor patio.

A lobby with stone walls, leather sofas, a Christmas tree, and a dining area.

A modern living area with a stone accent wall, a wooden herringbone pattern wall, a flat-screen TV, and a seating area with sofas and chairs.

A modern indoor space with a pool view, featuring a stone accent wall, contemporary furniture, and a large window.

19. Best Western Courtview Hotel

Galloway Village, 5 km from Lester E. Cox Medical Center South

Michelle

฿2,857

฿3,243 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio with stone walls, round tables, chairs, and umbrellas.

A modern hotel room with a stone accent wall, a flat-screen TV, a fireplace, a sofa, a dining area, and a patterned carpet.

A Fairfield Inn & Suites Marriott hotel with a modern design, featuring a prominent entrance and a parking lot.

A modern living room with a wooden dining table, comfortable seating, a stone accent wall, and a large window.

20. Fairfield Inn & Suites by Marriott Springfield North

Doling, 10.7 km from Lester E. Cox Medical Center South

Kristal

฿3,400

฿3,939 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare popular hotels close to Lester E. Cox Medical Center South

Property	Property class	Guest rating
Hampton Inn Springfield-South	9.4 Exceptional 717 reviews	View
Homewood Suites by Hilton Springfield Medical District	9.4 Exceptional 565 reviews	View
Holiday Inn Express and Suites Springfield Medical District by IHG	9.4 Exceptional 1,000 reviews	View
Candlewood Suites Springfield-Medical District	9.2 Wonderful 434 reviews	View
Element by Marriott Springfield South	9.2 Wonderful 158 reviews	View

Top Lester E. Cox Medical Center South Hotel Reviews

Bass Pro Shops Angler's Lodge

10/10 Excellent

"Great Hotel...good restaurant across the road and fantatstic shop"

The Bradford Hotel, an Ascend Collection Hotel

10/10 Excellent

"Nice clean room"

Quality Inn & Suites

8/10 Good

"Not a luxurious stay, but it was clean and comfortable with a decent breakfast. The location was pretty handy as well."

Lamplighter Inn & Suites - South

8/10 Good

"Room was clean but had to get towels at desk. Staff went beyond duty to help. Didn’t find a hot tub. Not many shops close. Breakfast was best on Saturday and Sunday."

Comfort Inn South - Springfield

8/10 Good

"Rooms were clean and refreshed. closet door latch was broke, and toilet wobbled. Notified desk at end of stay, and stated they would be handled. :-)"

Homewood Suites by Hilton Springfield Medical District

8/10 Good

"Good"

Holiday Inn Express and Suites Springfield Medical District by IHG

10/10 Excellent

"This is gonna be our go to stay in Springfield. The staff was friendly. The place was very clean. Our room was very clean. We had a standard two queen room that was huge. The bed was super comfortable. The pool area and hot tub was super clean and very nice and their breakfast was really good."

Candlewood Suites Springfield-Medical District

10/10 Excellent

"There was some issues with smells from other unit, people use these for extended stays and must cook alot in them, so we woke up to burning smells throughout the night and early morning."

Sleep Inn Springfield South I60 near Medical District

10/10 Excellent

"The staff was so friendly and the breakfast was great. Very convenient location for travelers - places to eat and gas up so nearby."

Frequently asked questions

What's the area like around Lester E. Cox Medical Center South?

Lester E. Cox Medical Center South is located in a welcoming area of Springfield that travellers like for its sporting events and opera houses. If you're looking for a convenient place to stay, take a look at the 19 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay close to Lester E. Cox Medical Center South?

Residence Inn by Marriott Springfield is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.5 mi (0.8 km) from Lester E. Cox Medical Center South. Other good choices close by include The Bradford Hotel, an Ascend Collection Hotel and Extended Stay America Select Suites Springfield South.

How many hotels are there close to Lester E. Cox Medical Center South?

Expedia has 19 hotels and other accommodation options within a mile from Lester E. Cox Medical Center South.

If I need to cancel the hotel reservation for my stay near Lester E. Cox Medical Center South, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to review the best deals available near Lester E. Cox Medical Center South.

What can I see and do near Lester E. Cox Medical Center South?

You'll want to browse the exhibits at Springfield Art Museum and Discovery Center of Springfield. Sights like Abou Ben Adhem Shrine and Landers Theater highlight some of the local culture. You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden.

Search Hotels Near Lester E. Cox Medical Center South, Springfield

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Holiday Inn Express and Suites Springfield Medical District by IHG

4. Candlewood Suites Springfield-Medical District

5. Element by Marriott Springfield South

6. Hilton Garden Inn Springfield, MO

7. Residence Inn by Marriott Springfield

8. La Quinta Inn & Suites by Wyndham Springfield South

9. MainStay Suites Springfield South - Battlefield Rd

10. Comfort Inn South - Springfield

11. The Bradford Hotel, an Ascend Collection Hotel

12. Sleep Inn Springfield South I60 near Medical District

13. Extended Stay America Select Suites Springfield South

14. Clarion Pointe Springfield Southeast

15. Drury Inn & Suites Springfield, MO

16. Hampton Inn Springfield-Southeast

17. SpringHill Suites by Marriott Springfield North

18. Holiday Inn Express & Suites Springfield North by IHG

19. Best Western Courtview Hotel

20. Fairfield Inn & Suites by Marriott Springfield North

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

Bass Pro Shops Angler's Lodge

The Bradford Hotel, an Ascend Collection Hotel

Quality Inn & Suites

Lamplighter Inn & Suites - South

Comfort Inn South - Springfield

Homewood Suites by Hilton Springfield Medical District

Holiday Inn Express and Suites Springfield Medical District by IHG

Candlewood Suites Springfield-Medical District

Sleep Inn Springfield South I60 near Medical District

Frequently asked questions