Isla Santa María Holiday Packages - Save on Isla Santa María Flight & Hotel

Photo by Delen Wong

Plan, book, travel with confidence
Better together
Save up to ฿27,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top hotels in Isla Santa María

Hotel Fiesta

Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos

Fully refundableReserve now, pay when you stay

฿4,665

฿4,665 total

28 Sept - 29 Sept

9/10 Wonderful! (439 reviews)

"Hot tub worked"

Reviewed on 24 Sept 2026

Finch Bay Galapagos Hotel

Barrio Punta Estrada Puerto Ayora Galapagos

฿18,378

฿20,267 total

11 Oct - 12 Oct

Maidith Galapagos Inn

Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos

฿4,327

฿4,327 total

28 Sept - 29 Sept

10/10 Exceptional! (165 reviews)

"Great hotel and clean rooms. Had a comfortable stay. Breakfast was very good with a decent spread. The hotel staff was friendly and if you’re looking for a personal touch this is the hotel to stay!"

Reviewed on 23 Sept 2026

See all 219 properties in Isla Santa María

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Isla Santa María attractions

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.

See properties

Two seals resting on a sandy beach with a rocky shoreline and a sunset in the background.

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.

See properties