A long bridge spanning a river, surrounded by lush greenery and fields.

Search Spa Hotels in Greenville

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Greenville Spa Hotels

Tonight
7 Oct - 8 Oct
Tomorrow
8 Oct - 9 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Greenville hotels with a spa

A salon setting with two people seated, a table with various skincare products, a vase with flowers, and neatly rolled towels in the background.
A table set for a formal dinner with white tablecloths, candles, and floral centerpieces.
A restaurant with multiple dining areas, including booths and tables, with overhead lighting and a bar in the background.
A spacious lobby with a grand chandelier, a round seating area, and a second-floor balcony.

1. Harlow's Casino Resort & Spa

Harlow's Casino Resort & Spa
Greenville
  • Relax in riverside luxury with spa treatments featuring hot stone massages, aromatherapy, and deep-tissue therapies in spacious suites.
฿3,903
฿4,293 total
includes taxes & fees
11 Oct - 12 Oct
Harlow's Casino Resort & Spa
View all properties

Choose what matters most at spa hotels in Greenville

Pool
Hot tub
Breakfast included
4 stars
5 stars

Top Greenville Hotel Reviews

Frequently asked questions

Looking to holiday at a spa hotel in Greenville?
Forget the stress of everyday life and book yourself a lush spa hotel. Enjoy the live music scene and restaurants in Greenville—your day trip starts here. Enjoy the entertainment choices and riverfront during your holiday. Spa hotels are the perfect way to take a break from your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in Greenville?
Harlow's Casino Resort & Spa is a top spa hotel featuring 3 restaurants, 3 bars, a casino and a 24-hour fitness centre. Enjoy a facial, body scrub or detox wrap at the on-site spa.
How many spa hotels are there in Greenville?
Among Expedia's 18 accommodation options in Greenville, there is 1 spa hotel.
What's there to see and do in Greenville?
Take in some sights and attractions while you're in Greenville by visiting Trop Casino Greenville, Greenville Country Club and Harlow's Casino Resort & Spa. If you have a bit of extra time while you're in the area, you might want to check out Mississippi River and 1927 Flood Museum.
What is a Greenville spa hotel?
Spa hotels in Greenville feature on-site spas offering services such as couples massages and a selection of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your holiday.

Explore a world of travel with Expedia