A historic stone fortress with a central dome and surrounding walls.

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Check availability on Colon Luxury Hotels

Tonight
22 Aug - 23 Aug
Tomorrow
23 Aug - 24 Aug
Next weekend
28 Aug - 30 Aug
In two weeks
4 Sep - 6 Sep

Our top choices for Colon luxury hotels

1. Luma Rentals Apartments

Luma Rentals Apartments
Bella Vista
฿4,084
฿6,126 total
includes taxes & fees
23 Aug - 24 Aug
Luma Rentals Apartments

2. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
฿3,193
฿3,513 total
includes taxes & fees
28 Aug - 29 Aug
Courtyard by Marriott Panama Metromall

3. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
฿8,783
฿9,661 total
includes taxes & fees
3 Sept - 4 Sept
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

4. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
Costa del Este
฿2,940
฿4,959 total
includes taxes & fees
23 Aug - 24 Aug
Corporate Stays Arcadia | Executive Furnished Apartments

5. The Westin Panama

The Westin Panama
Costa del Este
฿7,277
฿8,005 total
includes taxes & fees
19 Sept - 20 Sept
The Westin Panama

6. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
฿5,734
฿6,307 total
includes taxes & fees
31 Aug - 1 Sept
Sheraton Grand Panama

7. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
  • Spectacular waterfront luxury at Panama Canal hotel with premium dining and dual pools.
฿3,105
฿3,416 total
includes taxes & fees
5 Sept - 6 Sept
Radisson Hotel Panama Canal

8. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
  • Luxury redefined in Panama City with rooftop pool, premium dining, and concierge services to elevate your urban escape.
฿5,260
฿5,786 total
includes taxes & fees
28 Aug - 29 Aug
Marriott Panama Hotel

9. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
฿8,860
฿9,746 total
includes taxes & fees
11 Sept - 12 Sept
JW Marriott Panama

10. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
฿8,894
฿8,894 total
includes taxes & fees
23 Aug - 24 Aug
Dreams Playa Bonita Panama - All Inclusive
View all properties

Top Colon Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"The staff was ve4y pleasant"
Magaredad 5-night trip
Posted 3 hours ago
Hotel Riu Plaza Panama
Renaissance Panama City Hotel

Renaissance Panama City Hotel

10/10 Excellent
"The staff was wonderful and the amenities were a plus the house keeper that was assigned to our room 419 was very respectful and kind I would definitely recommend people to stay at this hotel looking forward to returning"
Corey 5-night trip
Posted 13 hours ago
Renaissance Panama City Hotel
Decapolis Hotel Panama City

Decapolis Hotel Panama City

8/10 Good
"Clean room, Excellent breakfast options and tasty"
Diana 7-night trip
Posted 19 hours ago
Decapolis Hotel Panama City
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

10/10 Excellent
"Buffet breakfast was switched up daily, room was spacious and clean, staff was very accommodating, great access to nearby mall and good location for shuttle pickup for excursions. Would definitely stay again and highly recommend."
Shereen 6-night trip
Posted 22 hours ago
Courtyard by Marriott Panama Multiplaza Mall
Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

10/10 Excellent
"Rainforest views and Hammock in the balcony"
Rajdeep 1-night trip
Posted 3 days ago
Gamboa Rainforest Reserve

Frequently asked questions

Are you looking for a luxury hotel for your Colon holiday?
Use Expedia to arrange your flight to Panama City (PAC-Marcos A. Gelabert Intl.) airport or Balboa (BLB-Panama Pacifico Intl.) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Colon offers. Colon has some interesting things to see and do including Colon 2000 and Colon Free Zone, so you might want to take in the local sights during your visit.
What's the best luxury place to stay in Colon?
Sand Diamond Hotel is a luxury hotel with ski-in/ski-out access and a casino, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in Colon?
Planning for the weather is an important factor for making your trip to Colon a success, especially when you're splurging. The hottest months are usually May and September, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Colon are November, July, August and October, with each month seeing an average of 350 mm of rainfall.
What's there to see and do in Colon?
Take in the sights and attractions that Colon offers with a visit to Colon 2000, Colon Free Zone and Gamboa Rainforest Resort. If you have extra time while you're in the area, you might want to see Galeta Island Marine Education Center and Fort San Lorenzo.
How can I get around Colon?
It's easier to get around town in style when you know your options. If you want to venture outside the area, hop aboard a train at Colon Atlantic Passenger Station.