A cityscape with various buildings, including a prominent skyscraper and several mid-rise structures.

Search Luxury Hotels in Winston-Salem

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Winston-Salem Luxury Hotels

Tonight
14 Oct - 15 Oct
Tomorrow
15 Oct - 16 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Winston-Salem luxury hotels

A well-organized bar area with shelves, bottles, and a large 'C.' sign.
A building entrance with a decorative facade, a sign indicating it's a hotel, and a visible street view.
A modern living room with a blue sofa, a round coffee table, and a dining area with teal chairs.
A modern living room with a marble coffee table, wine bottles, glasses, and a sofa with decorative pillows.

1. Kimpton Cardinal Hotel by IHG

Kimpton Cardinal Hotel by IHG
Winston-Salem
  • Boutique luxury flourishes in this Winston-Salem gem where vintage charm meets modern elegance in the heart of the city.
฿6,109
฿6,903 total
includes taxes & fees
25 Oct - 26 Oct
Kimpton Cardinal Hotel by IHG
A grand lobby with a central fountain, multiple staircases, and elegant chandeliers.
A grand lobby with a central staircase, multiple seating areas, and a chandelier.
A large, multi-story hotel with a prominent tower and a well-lit facade.
An outdoor seating area with a stone fire pit surrounded by sofas and chairs, string lights overhead, and a building in the background.

2. Grandover Resort & Spa, a Wyndham Grand Hotel

Grandover Resort & Spa, a Wyndham Grand Hotel
Sedgefield
  • Wyndham Grand Hotel features championship golf, spa treatments, and top service in scenic Greensboro.
฿6,676
฿8,244 total
includes taxes & fees
13 Nov - 14 Nov
Grandover Resort & Spa, a Wyndham Grand Hotel
A spacious lobby with high ceilings, large columns, a staircase, and modern furnishings.
A modern hotel lobby with a sofa area, round tables, and a decorative partition.
A modern bar area with multiple seating options, a well-stocked liquor display, and a flat-screen TV mounted on the wall.
A modern hotel room with a large bed, a desk with a chair, a television, and a wooden entertainment unit.

3. Marriott Greensboro Downtown

Marriott Greensboro Downtown
Downtown Greensboro
฿6,344
฿7,153 total
includes taxes & fees
13 Nov - 14 Nov
Marriott Greensboro Downtown
A spacious indoor area with multiple dining tables and chairs, a central staircase, and large windows allowing natural light.
A hotel interior with a view of a garden through large windows, a staircase with a railing, and seating areas.
A spacious lobby with a high ceiling, a central staircase, and multiple seating areas.
A bar area with a long wooden counter, multiple stools, and hanging pendant lights. There are large windows with a view of greenery outside.

4. Proximity Hotel

Proximity Hotel
Greensboro
฿9,353
฿10,545 total
includes taxes & fees
22 Oct - 23 Oct
Proximity Hotel
A hotel with a prominent entrance, a covered walkway, and a flag on top.
A commercial kitchen with stainless steel appliances and a tiled backsplash.
An outdoor courtyard with a circular seating arrangement, a central fountain, and surrounding greenery.
A lobby with leather chairs, a central table with a vase of orchids, and two floor lamps.

5. O.Henry Hotel

O.Henry Hotel
Greensboro
  • Opulent hotel near Greensboro offers deep soaking tubs, designer amenities, and seasonal pool.
฿11,044
฿12,452 total
includes taxes & fees
10 Nov - 11 Nov
O.Henry Hotel
A geodesic dome structure with a solar panel on top, surrounded by a wooden deck with chairs and a table.
A bed with a textured blanket, a bedside lamp, and a small round table.
An aerial view of a residential area with houses, roads, and a large building with a flat roof.
An aerial view of a property with four dome-shaped structures surrounded by dense greenery and winding roads.

6. Pilot Mountain Glamping Resort

Pilot Mountain Glamping Resort
Pinnacle
฿5,057
฿5,702 total
includes taxes & fees
8 Nov - 9 Nov
Pilot Mountain Glamping Resort
View all properties

Top Winston-Salem Hotel Reviews

Suburban Studios Winston Salem-University Parkway

Suburban Studios Winston Salem-University Parkway

10/10 Excellent
"I choose this site because it was 6.2 miles from the Forsyth Medical Center. I live too far away so I needed a room. It was clean and well cared for. The parking lot is lite up, fully, with LED lighting a night. Handicap parking. Parking in front of the rooms. The room was neat & spotless, no bugs either. There is a small burea, a shelf over it; a table & 2 chairs; nice size refrigerator; 2 coiled areas to cook on a counter with a sink; storage cabinets; full bathroom with out stains; no pealing paint on walls/clean and cared for. The staff are friendly & helpful. They are working on it constantly. The price is correct for a minimalist room. No breakfast, no pool, just a basic room. Great if it’s all you need or want. I would 100% stay there again. I felt safe & thankful."
Marie 1-night trip
Posted 16 hours ago
Suburban Studios Winston Salem-University Parkway
Hawthorne Inn and Conference Center

Hawthorne Inn and Conference Center

10/10 Excellent
"The staff were so helpful"
Lun 1-night trip
Posted 16 hours ago
Hawthorne Inn and Conference Center
Sleep Inn Hanes Mall

Sleep Inn Hanes Mall

10/10 Excellent
"This was one of my best stays at a hotel and i been staying at them for over 40 years and this was the phenomenal outstanding staff wonderful service I would stay here every chance I get sad they out due Hilton, Marriot's, Holiday Inn, all tops hotel I ever stayed in"
Earlina 2-night trip
Posted 17 hours ago
Sleep Inn Hanes Mall
Winston-Salem Marriott

Winston-Salem Marriott

10/10 Excellent
"Helpful. Great valet service"
Josd Manuel 1-night trip
Posted 18 hours ago
Winston-Salem Marriott

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Winston-Salem?
While you're visiting, you might want to think about enjoying the museums and sporting events, which Winston-Salem is known for.
What's the best luxury accommodation option in Winston-Salem?
Kimpton Cardinal Hotel by IHG is a luxury hotel with a deli and in-room massages, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in Winston-Salem?
Planning for the weather is a good way to make your trip to Winston-Salem relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 6°C. Average annual precipitation for Winston-Salem is 1289 mm.
What's there to see and do in Winston-Salem?
When you're in Winston-Salem, enjoy exploring the sights and attractions here including Old Salem, Truist Stadium and Bowman Gray Stadium. If you have some spare time during your trip, you might want to check out Lawrence Joel Veterans Memorial Coliseum and Truist Field.

Explore a world of travel with Expedia