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Our top choices for St. Luke's Hospital hotels

Marriott St. Louis West

Marriott St. Louis West
3.5 star property
1.1 km from St. Luke's Hospital
8.4 out of 10, Very good, (1000)
"Needs to fix the heat "
United States
Falah
The price is ฿4,688
฿5,449 total
includes taxes & fees
15 Jan - 16 Jan 2026
Marriott St. Louis West

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
5 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (1001)
"Wonderful staff, easy parking, nice breakfast, very comfortable room."
United States
Carole
The price is ฿3,817
฿4,428 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hyatt Place St. Louis/Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
5.1 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (1038)
"Absolutely amazing stay very nice play our family stays there every time very kid friendly"
United States
Matthew
The price is ฿4,034
฿4,679 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel St. Louis Chesterfield

Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Fairfield Inn & Suites by Marriott St. Louis Chesterfield
3.0 star property
4.2 km from St. Luke's Hospital
9.0 out of 10, Wonderful, (1002)
"Rooms clean, pool area nice and warm, staff excellent."
United States
Demontra
The price is ฿3,139
฿3,641 total
includes taxes & fees
11 Jan - 12 Jan 2026
Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur
3.0 star property
Creve Coeur, 5.3 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (1001)
"Excellent hotel! "
United States
Sara
The price is ฿3,561
฿4,139 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel St. Louis Creve Coeur

Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield
3.0 star property
4.2 km from St. Luke's Hospital
8.0 out of 10, Very good, (1028)
"Clean room,Friendly staff, Good location and Good Breakfast options"
United States
Micheal
The price is ฿2,700
฿3,132 total
includes taxes & fees
5 Jan - 6 Jan 2026
Sonesta ES Suites St. Louis - Chesterfield

Hampton Inn St. Louis/Chesterfield

Hampton Inn St. Louis/Chesterfield
3.5 star property
5 km from St. Luke's Hospital
8.6 out of 10, Excellent, (1001)
"Clean room, comfy bed & friendly staff!!"
United States
Carole
The price is ฿2,672
฿3,099 total
includes taxes & fees
19 Jan - 20 Jan 2026
Hampton Inn St. Louis/Chesterfield

Holiday Inn St. Louis - Creve Coeur by IHG

Holiday Inn St. Louis - Creve Coeur by IHG
3.0 star property
5.3 km from St. Luke's Hospital
8.8 out of 10, Excellent, (351)
"Overall great stay, very clean and updated. Would stay again. "
United States
Alisa
The price is ฿3,662
฿4,377 total
includes taxes & fees
27 Jan - 28 Jan 2026
Holiday Inn St. Louis - Creve Coeur by IHG

Courtyard by Marriott St Louis Creve Coeur

Courtyard by Marriott St Louis Creve Coeur
3.0 star property
Creve Coeur, 5.6 km from St. Luke's Hospital
8.8 out of 10, Excellent, (1002)
"Clean room and very helpful staff"
United States
Amy
The price is ฿3,786
฿4,401 total
includes taxes & fees
8 Jan - 9 Jan 2026
Courtyard by Marriott St Louis Creve Coeur

Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
3.0 star property
7.3 km from St. Luke's Hospital
9.6 out of 10, Exceptional, (199)
"Very clean and safe place, wonderful location "
United States
Ashley
The price is ฿5,866
฿6,862 total
includes taxes & fees
5 Jan - 6 Jan 2026
Residence Inn by Marriott St. Louis Chesterfield

Homewood Suites by Hilton St. Louis-Chesterfield

Homewood Suites by Hilton St. Louis-Chesterfield
3.0 star property
4.6 km from St. Luke's Hospital
8.4 out of 10, Very good, (1000)
"Clean, convenient location to shopping."
United States
Kelly
The price is ฿3,512
฿4,073 total
includes taxes & fees
16 Jan - 17 Jan 2026
Homewood Suites by Hilton St. Louis-Chesterfield

Courtyard by Marriott St. Louis West County

Courtyard by Marriott St. Louis West County
3.0 star property
6.5 km from St. Luke's Hospital
9.0 out of 10, Wonderful, (454)
"Business friendly great staff."
United States
Elijah
The price is ฿4,070
฿4,680 total
includes taxes & fees
3 Jan - 4 Jan 2026
Courtyard by Marriott St. Louis West County

AC Hotel by Marriott St. Louis Chesterfield

AC Hotel by Marriott St. Louis Chesterfield
3.5 star property
5.9 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (248)
"Wonderful reception and breakfast staff!!!"
United States
Timothy
The price is ฿3,941
฿4,572 total
includes taxes & fees
4 Jan - 5 Jan 2026
AC Hotel by Marriott St. Louis Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
4.0 star property
5.8 km from St. Luke's Hospital
8.6 out of 10, Excellent, (1002)
"Great hotel!"
United States
John
The price is ฿3,792
฿4,398 total
includes taxes & fees
23 Jan - 24 Jan 2026
DoubleTree by Hilton Hotel St. Louis - Chesterfield

Residence Inn by Marriott St. Louis West County

Residence Inn by Marriott St. Louis West County
3.0 star property
6.5 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (246)
"Very dog friendly place to stay"
United States
William
The price is ฿4,301
฿4,946 total
includes taxes & fees
23 Jan - 24 Jan 2026
Residence Inn by Marriott St. Louis West County

Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport
2.5 star property
7.8 km from St. Luke's Hospital
9.2 out of 10, Wonderful, (812)
"Everything was great "
United States
Alan
The price is ฿3,796
฿4,403 total
includes taxes & fees
3 Jan - 4 Jan 2026
Fairfield Inn & Suites St Louis Westport

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
8.7 km from St. Luke's Hospital
8.8 out of 10, Excellent, (1003)
"Great room, great amenities!"
United States
Linda or James
The price is ฿4,046
฿4,714 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton St. Louis Frontenac

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
2.5 star property
9.4 km from St. Luke's Hospital
9.0 out of 10, Wonderful, (1004)
"Great hotel!"
United States
Lorelei
The price is ฿3,290
฿3,828 total
includes taxes & fees
8 Jan - 9 Jan 2026
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield
3.0 star property
6.5 km from St. Luke's Hospital
8.2 out of 10, Very good, (787)
"Staff was informative during check-in. Room was clean and the TV even had WELCOME with my name on it. Would stay here again."
United States
Ida
The price is ฿3,035
฿3,532 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Chesterfield

Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield
3.0 star property
8.8 km from St. Luke's Hospital
9.0 out of 10, Wonderful, (579)
"Very clean and nice hotel! "
United States
Gina
The price is ฿3,600
฿4,189 total
includes taxes & fees
17 Jan - 18 Jan 2026
Courtyard by Marriott St. Louis Chesterfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Luke's Hospital Hotel Reviews

Hotels near other St. Luke's Hospital attractions

Frequently asked questions

What's the area like around St. Luke's Hospital?
St. Luke's Hospital is located in St. Louis. Travellers love the area for its great live music scene and top museums. You'll find 94 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay near St. Luke's Hospital?
Marriott St. Louis West is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an indoor pool. It's located just a short 0.7 mi (1.1 km) from St. Luke's Hospital. Other good options within 5 miles include Sonesta ES Suites St. Louis - Chesterfield and Fairfield Inn & Suites by Marriott St. Louis Chesterfield.
How many hotels can I expect to find near St. Luke's Hospital?
Expedia has 94 hotels and other accommodation options a few miles from St. Luke's Hospital.
If I need to cancel the hotel reservation for my stay near St. Luke's Hospital, will I receive a refund?
Yes, most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get top deals close to St. Luke's Hospital.
What can I see and do near St. Luke's Hospital?
You'll want to browse the collections at Myseum, American Kennel Club Museum of the Dog and Historic Aircraft Restoration Museum. Get outside and spend some time strolling around Lou Fusz Soccer Complex, Sophia M. Sachs Butterfly House and Faust Park. Attractions like Chesterfield Arts and Chesterfield Amphitheater highlight the local culture.