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Find hotels in Six Mile, SC from ฿2,170

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Tonight
25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Six Mile hotels

House (1 Bedroom) | Interior
Lake Keowee Access: Idyllic Six Mile Cabin!

Lake Keowee Access: Idyllic Six Mile Cabin!

Lake Keowee Access: Idyllic Six Mile Cabin!
3.0 star property
Six Mile
The price is ฿2,486
฿8,773 total
includes taxes & fees
28 Dec - 29 Dec
Lake Keowee Access: Idyllic Six Mile Cabin!
Property amenity
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very good, (1001)
"Clean room and staff were great’"
United States
Audrey
The price is ฿2,615
฿2,903 total
includes taxes & fees
28 Dec - 29 Dec
Best Western Plus Clemson Hotel & Conference Center
Aerial view
Lakeside Lodge Clemson

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1000)
"Great place to stay. "
United States
Gene
The price is ฿3,387
฿4,205 total
includes taxes & fees
26 Dec - 27 Dec
Lakeside Lodge Clemson
Lobby
Best Western Seneca-Clemson

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (642)
"The stay was amazing "
United States
Tabatha
The price is ฿2,615
฿2,877 total
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Seneca-Clemson
Exterior
Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (807)
"Very comfortable stay convenient to Greenville Spartanburg Airport."
United States
Rick
The price is ฿3,528
฿3,916 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn Anderson/ Alliance Business Park
Fireplace
Courtyard Marriott Clemson

Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
Clemson
9.0 out of 10, Wonderful, (523)
"Overall, great stay!"
United States
Lynn
The price is ฿3,698
฿4,105 total
includes taxes & fees
26 Dec - 27 Dec
Courtyard Marriott Clemson
Free buffet breakfast
Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC
2.5 star property
Anderson
8.4 out of 10, Very good, (1003)
"Check in staff was very nice & let us in a bit early which was a blessing after being on road "
United States
Lynette
The price is ฿3,468
฿3,850 total
includes taxes & fees
31 Dec - 1 Jan 2026
Country Inn & Suites by Radisson, Anderson, SC
Reception hall
The Inn at Patrick Square

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (785)
"Everything was clean staff was courteous and accommodating. "
United States
Stewart
The price is ฿4,630
฿5,140 total
includes taxes & fees
27 Dec - 28 Dec
The Inn at Patrick Square
Lobby
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very good, (1001)
"Great stay "
United States
Linda
The price is ฿3,189
฿3,539 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn & Suites Clemson - University Area
In-room safe, blackout curtains, soundproofing, iron/ironing board
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (743)
"Staff was amazing and our room was clean and comfortable. "
United States
Amanda R
The price is ฿5,252
฿5,830 total
includes taxes & fees
26 Dec - 27 Dec
The Shepherd Hotel Downtown Clemson
Reception
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.0 out of 10, Wonderful, (585)
"It was great. Room was clean and staff was friendly. "
United States
Veronica
The price is ฿3,201
฿3,553 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Coffee service
Comfort Suites Anderson-Clemson

Comfort Suites Anderson-Clemson

Comfort Suites Anderson-Clemson
2.5 star property
Anderson
8.4 out of 10, Very good, (1000)
"Clean, comfortable "
United States
Cheryl
The price is ฿3,331
฿3,698 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Anderson-Clemson
Lobby
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (798)
"Staff is amazing, hotel and amenities are great. "
United States
Shannon
The price is ฿3,032
฿3,336 total
includes taxes & fees
1 Jan - 2 Jan 2026
Tru by Hilton Seneca Clemson
Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers
Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson
2.5 star property
Anderson
9.0 out of 10, Wonderful, (566)
"Clean room staff was verynice!"
United States
Laura Jo
The price is ฿2,766
฿3,070 total
includes taxes & fees
1 Jan - 2 Jan 2026
Fairfield Inn & Suites by Marriott Anderson Clemson
Free daily buffet breakfast
Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
Clemson
8.8 out of 10, Excellent, (623)
"Room was awesome and great breakfast "
United States
Guy
The price is ฿3,408
฿3,782 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn Clemson-University Area
Outdoor pool
Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson
2.5 star property
Anderson
7.0 out of 10, Good, (845)
"Well lit parking and safe area around the hotel"
United States
Gregory
The price is ฿1,849
฿2,052 total
includes taxes & fees
18 Jan - 19 Jan 2026
Baymont by Wyndham Anderson Clemson
Lobby lounge
Inn @ Clemson

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.2 out of 10, Very good, (1004)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson
Exterior
Hilton Garden Inn Anderson

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (680)
"Staff were great. Room was clean."
United States
gary
The price is ฿3,287
฿3,649 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hilton Garden Inn Anderson
Fireplace
Brook Trout Inn

Brook Trout Inn

Brook Trout Inn
3.5 star property
Sapphire
9.6 out of 10, Exceptional, (560)
"Wonderful stay, we will be back!"
United States
Suzanne
The price is ฿4,068
฿4,546 total
includes taxes & fees
21 Jan - 22 Jan 2026
Brook Trout Inn
Meeting facility
The Abernathy of Clemson

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (557)
"location is amazing! "
United States
colleen
The Abernathy of Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Six Mile attractions

Keowee Springs Golf Course

Enjoy a round of golf in Six Mile at Keowee Springs Golf Course.
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Mile Creek Park

Explore the great outdoors at Mile Creek Park, a lovely green space in Six Mile.
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Learn more about Six Mile

Lake Keowee offers pristine waters for boating, fishing, and swimming with several public access points around Six Mile. Hikers can explore nearby Table Rock State Park's trails leading to spectacular mountain views and refreshing waterfalls.

See all hotels in Six Mile
Lake Keowee is a man–made reservoir in the United States in the state of South Carolina. It was created to serve the needs of a power utility as well as public recreational purposes. One of my favorite places to go in the summer. The water really is that color.
Photo by Deidree DeHart
Open Photo by Deidree DeHart

Top Six Mile Hotel Reviews

Comfort Suites Piedmont - Greenville South

Comfort Suites Piedmont - Greenville South

10/10 Excellent
"Staff was super friendly "
Brittany 1-night trip
Posted 4 days ago
Comfort Suites Piedmont - Greenville South

More cheap stays in Six Mile

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC
The price is ฿1,955 per night from 28 Dec to 29 Dec
฿1,955
฿2,170 total
28 Dec - 29 Dec
includes taxes & fees
7.6/10 Good! (1,000 reviews)

Frequently asked questions

Where is the best place to stay in Six Mile?
Best Western Plus Clemson Hotel & Conference Center, located 8.2 mi (13.2 km) from the heart of Six Mile, is a top choice for your stay, based on our traveller data. Two other choices for your trip to the area are Days Inn by Wyndham Anderson and Quality Inn Seneca Clemson Area US-123. See all available top hotels, or vacation rentals in Six Mile.
If I need to cancel my hotel reservation in Six Mile, will I receive a refund?
Yes! Most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Six Mile.
What are some hotels with pools in Six Mile?
Best Western Plus Clemson Hotel & Conference Center: Hotel located near Clemson University. Offers free self parking, a seasonal outdoor pool and a 24-hour fitness centre. Days Inn by Wyndham Anderson and Quality Inn Seneca Clemson Area US-123 are two additional hotels that offer an on-site pool. View all hotels with pools in Six Mile.
How is it staying in Six Mile?
Travellers to Six Mile will find plenty to explore and enjoy. In Six Mile, there are 71 hotels and other accommodation options to choose from. Find out more about Six Mile.
What are the top places to visit in Six Mile?
The picturesque setting of Lake Keowee and Mile Creek Park exemplify the area's natural beauty. Additionally, you might want to add Keowee Springs Golf Course to your itinerary. Take a look at what more there is to see and do in Expedia's Six Mile guide.
What's the weather like in Six Mile?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Six Mile is 1561 mm.

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