Search Hotels in Santiago, Puebla

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santiago hotels

Living Up

Living Up
3.0 star property
Santiago
8.0 out of 10, Very good, (1)
"La habitación estuvo muy bonita y la atención del personal dentro de las instalaciones muy gentil y servicial."
Mexico
Daniel
The price is ฿721
฿1,119 total
includes taxes & fees
22 Dec - 23 Dec
Living Up

Loft Carrara

Loft Carrara
2.0 star property
18.4 km from Santiago
10.0 out of 10, Exceptional, (6)
"Muy bonito el lugar y limpio"
Mexico
Rosa
The price is ฿7,212
฿9,119 total
includes taxes & fees
21 Dec - 22 Dec
Loft Carrara

Villa Toscana ValQuirico Lofts & Suites Hotel Boutique

Villa Toscana ValQuirico Lofts & Suites Hotel Boutique
3.5 star property
18.3 km from Santiago
9.6 out of 10, Exceptional, (365)
"The rooms were very nice, though the area is made to look like Italian towns tbe rooms were large and confortable highly recommend a stay at this hotel "
United States
Jose
The price is ฿4,552
฿5,371 total
includes taxes & fees
8 Jan - 9 Jan 2026
Villa Toscana ValQuirico Lofts & Suites Hotel Boutique

Hotel Teresita

Hotel Teresita
2.5 star property
Puebla Historic Center, 1.2 km from Santiago
8.4 out of 10, Very good, (302)
"A bit hot in the rooms and voices carry in the lobby. Overall a great stay."
United States
Marlene
Hotel Teresita

Hotel Las Iglesias, Cholula

Hotel Las Iglesias, Cholula
3.0 star property
10.7 km from Santiago
8.8 out of 10, Excellent, (549)
"The room was excellent and the staff were very friendly and helpful. We truly loved this hotel. "
United States
Rogelio
Hotel Las Iglesias, Cholula

Posada Guadalupe

Posada Guadalupe
2.0 star property
Puebla Historic Center, 1.3 km from Santiago
8.6 out of 10, Excellent, (314)
"Great Hotel location, just Puebla downtown. Will stay again. "
United States
Sergio
Posada Guadalupe

Fiesta Inn Express Puebla Explanada

Fiesta Inn Express Puebla Explanada
3.0 star property
7.5 km from Santiago
9.4 out of 10, Exceptional, (993)
"Great location"
United States
Epifania
The price is ฿1,884
฿2,243 total
includes taxes & fees
22 Dec - 23 Dec
Fiesta Inn Express Puebla Explanada

Hotel Aroma 406

Hotel Aroma 406
2.5 star property
Puebla Historic Center, 1.7 km from Santiago
8.4 out of 10, Very good, (145)
"Clean room"
United States
Severiano
Hotel Aroma 406

Comfort Inn Puebla Centro Histórico

Comfort Inn Puebla Centro Histórico
3.0 star property
Puebla Historic Center, 0.5 km from Santiago
9.0 out of 10, Wonderful, (1002)
"Great Staff"
United States
Susana
The price is ฿1,931
฿2,298 total
includes taxes & fees
24 Dec - 25 Dec
Comfort Inn Puebla Centro Histórico

La Quinta Puebla

La Quinta Puebla
3.0 star property
7.1 km from Santiago
7.8 out of 10, Good, (236)
"Wi-fi connection is not always stable but staff was good"
United States
Juan
The price is ฿792
฿943 total
includes taxes & fees
21 Dec - 22 Dec
La Quinta Puebla

Hotel Marques Del Angel

Hotel Marques Del Angel
4.0 star property
Puebla Historic Center, 1.1 km from Santiago
9.4 out of 10, Exceptional, (280)
"Excellent service "
United States
Mayra
Hotel Marques Del Angel

Hotel Diana

Hotel Diana
3.5 star property
Puebla Historic Center, 1.1 km from Santiago
9.0 out of 10, Wonderful, (689)
"All in all excellent."
Germany
Robert
Hotel Diana

HOTEL SANTIAGO

HOTEL SANTIAGO
2.5 star property
Puebla Historic Center, 1.4 km from Santiago
9.2 out of 10, Wonderful, (160)
"H Santiago is located 1/2 block from the Zocalo and Cathedral. Plenty of shopping options and affordable eateries - some of the restaurants in this area are pricey. Staff are attentive and certainly keep the areas and room clean."
United States
Jose
HOTEL SANTIAGO

Sleep Inn Puebla Centro Histórico

Sleep Inn Puebla Centro Histórico
3.0 star property
Puebla Historic Center, 2.1 km from Santiago
8.6 out of 10, Excellent, (885)
"Everything was great except for the pillows they were too flat. The room was large in spacious. The food was great."
United States
Mary
The price is ฿1,672
฿1,990 total
includes taxes & fees
4 Jan - 5 Jan 2026
Sleep Inn Puebla Centro Histórico

NH Puebla Finsa

NH Puebla Finsa
3.5 star property
6.7 km from Santiago
9.2 out of 10, Wonderful, (371)
"good place to stay on a budget."
Mexico
Josué Elías Pérez
The price is ฿1,467
฿1,746 total
includes taxes & fees
11 Jan - 12 Jan 2026
NH Puebla Finsa

Hotel Panamerican

Hotel Panamerican
3.0 star property
1 km from Santiago
8.4 out of 10, Very good, (920)
"It was super nice, the staff were very attentive and polite, and the place was very clean and tidy. It also has many amenities. We would definitely go back!"
Canada
Kevin
The price is ฿1,376
฿1,637 total
includes taxes & fees
22 Dec - 23 Dec
Hotel Panamerican

Casona María

Casona María
4.0 star property
Barrio De Analco, 2.4 km from Santiago
9.4 out of 10, Exceptional, (450)
"I made a mistake in selecting Casona Maria for my visit to Puebla. It's a mistake I won't make again."
United States
Jerold
The price is ฿4,690
฿5,581 total
includes taxes & fees
21 Dec - 22 Dec
Casona María

HOTEL MARGARITA

HOTEL MARGARITA
3.0 star property
Puebla Historic Center, 0.7 km from Santiago
9.2 out of 10, Wonderful, (82)
"We liked the decorations and the structure. The personel at the front desk is polite and very attentive."
United States
ROBERTO
HOTEL MARGARITA

Hotel Sofia

Hotel Sofia
2.5 star property
Puebla Historic Center, 1.1 km from Santiago
8.2 out of 10, Very good, (540)
"Excelente"
Mexico
Dante
The price is ฿998
฿1,187 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Sofia

Hotel Isabel

Hotel Isabel
3.0 star property
Puebla Historic Center, 1.2 km from Santiago
9.0 out of 10, Wonderful, (1001)
"Love the closeness to everything and food options around the area. Staff was very attentive to mine and my elderly mothers needs. Will definitely be back"
United States
Juan
The price is ฿1,500
฿1,785 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santiago

Find the best Santiago areas for the activities you enjoy most.

Puebla Historic Center

Travellers come to Puebla Historic Center for its abundant dining options, and you can see top attractions like Zócalo de Puebla and Los Sapos Bazaar while you're in town.

Cholula

Discover a beautiful colonial city with a collection of ornate churches and an ancient history that is inscribed into archaeological sites and cultural relics.

Angelópolis

Angelópolis is noteworthy for its shopping, and you can make a stop at top attractions like Angelopolis Commercial Center and Metropolitan Auditorium.

Cholula Centro

If you're spending some time in Cholula Centro, Zócalo and San Gabriel Convent are top sights worth seeing.

Lomas de Angelópolis

While Lomas de Angelópolis may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like International Baroque Museum and Museo de Artes Populares.

Top Santiago Hotel Reviews

Frequently asked questions

What's it like in Santiago?
You'll be sure to have fun exploring Puebla's Santiago neighbourhood.
If I need to cancel my hotel reservation in Santiago, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to get top deals in Santiago.
What is there to do in this Puebla neighbourhood?
Plaza de Revolución, Museum of the Mexican Army and Air Force and Uriarte Talavera are just a few of the places to visit in and around Santiago. Profetica and Bello Museum are also worth a visit when you're out sightseeing in Puebla.

Explore a world of travel with Expedia