A modern building with a unique triangular roof and a central spire.

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Check prices for these dates

This weekend
11 Sep - 13 Sep
Next weekend
18 Sep - 20 Sep

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Our top choices for Santa Lucia hotels

Rooftop terrace

1. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (292 reviews)
"Lovely hotel in a great spot, very helpful staff."
Australia
Mandy
The price is ฿7,520
฿8,654 total
includes taxes & fees
13 Sept - 14 Sept
Caportigia Boutique Hotel
Private kitchenette

2. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (286 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is ฿2,820
฿3,215 total
includes taxes & fees
5 Oct - 6 Oct
Nostos rooms & Apartments
Front of property

3. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (693 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is ฿3,835
฿4,372 total
includes taxes & fees
4 Oct - 5 Oct
Grande Albergo Alfeo
Porch

4. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is ฿2,473
฿2,819 total
includes taxes & fees
8 Oct - 9 Oct
Piccolo Hotel Casa Mia
Room

5. Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Wonderful property, excellent staff and the most amazing view from the apartment"
Australia
Anthony
The price is ฿7,747
฿8,904 total
includes taxes & fees
11 Sept - 12 Sept
Re Dionisio Luxury Suites
Suite, Balcony, Sea View

6. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"Clean room and well located."
United Kingdom
Hanna
The price is ฿3,800
฿4,331 total
includes taxes & fees
17 Sept - 18 Sept
Lakkios
Triple Room, Balcony | Balcony

7. B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (89 reviews)
"Great location and comfortable stay!"
United States
Rosa
The price is ฿2,924
฿3,333 total
includes taxes & fees
10 Oct - 11 Oct
B&B Nike
Superior Triple Room, Sea View | Terrace/patio

8. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (40 reviews)
"Beautiful accomodation, perfect location close to restauranys and attractions, clean room/all renovated with style, friendly personnel, nice view of the port"
Canada
Martine
The price is ฿7,060
฿8,048 total
includes taxes & fees
5 Oct - 6 Oct
Fortaleza Charme House
Suite

9. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (44 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is ฿4,014
฿4,576 total
includes taxes & fees
13 Sept - 14 Sept
Hotel Palazzo Cavalieri
Breakfast area

10. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (131 reviews)
"Hidden gem! The staff was extremely welcoming and helpful throughout our visit. Can't beat a room that looks out over the water and is a short walk into town. Would highly recommend!"
United States
James
The price is ฿8,247
฿9,454 total
includes taxes & fees
28 Sept - 29 Sept
Giuggiulena Villa
Lobby lounge

11. Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is ฿2,599
฿2,963 total
includes taxes & fees
1 Oct - 2 Oct
Regina Margherita
Double Room, 1 King Bed, Sea View, Tower

12. Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.0 out of 10, Very good, (2 reviews)
"Great hotel. Close to everything 15min walk into Ortigia and the excursions dock. The staff are incredibly helpful and thoughtful. Rooms are clean and nice. The balcony had great views of the water and ortigia. Highly recommend to anyone visiting Siracusa! "
United States
Aria
The price is ฿7,168
฿8,267 total
includes taxes & fees
12 Sept - 13 Sept
Casa Miranda Boutique
Room

13. B&B L'INFIORESCENZA

B&B L'INFIORESCENZA
Santa Lucia
6.8 out of 10, (3 reviews)
"Sehr gute Lage, aber das Mobiliar ist in extrem veralteten Zustand, Gestell des Bettes nicht fest, sehr wenig Platz, uralte, fleckige Matratze mit scharfen Federn, kein Internetzugang des WLANs und das Frühstück ist ein Witz. Für 1 Nacht gerade so in Ordnung, ansonsten nicht empfehlenswert."
Germany
Alessandra
The price is ฿1,515
฿2,163 total
includes taxes & fees
27 Sept - 28 Sept
B&B L'INFIORESCENZA
Classic Room | View from room

14. Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is ฿1,972
฿2,248 total
includes taxes & fees
3 Oct - 4 Oct
Gymnasium
Comfort Triple Room, Balcony, Ocean View | View from room

15. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is ฿3,344
฿3,812 total
includes taxes & fees
2 Oct - 3 Oct
Hotel Mediterraneo
Double Room

16. B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is ฿2,747
฿3,132 total
includes taxes & fees
20 Sept - 21 Sept
B&B Siracusa
View from room

17. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
9.8 out of 10, Exceptional, (17 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is ฿5,034
฿5,738 total
includes taxes & fees
2 Oct - 3 Oct
Calafatari B&B
Comfort Double Room

18. Melody rooms

Melody rooms
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
The price is ฿1,332
฿1,519 total
includes taxes & fees
29 Sept - 30 Sept
Melody rooms
Terrace/patio

19. Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
7.0 out of 10, Good, (2 reviews)
"Très belle chambre, mais forte odeur d’humidité, pas de FENÊTRE quartier type « cour des Miracles «  loin du centre historique, pas de supérette ou de restaurant dans le proche voisinage loin de toute commodité"
France
Philippe
The price is ฿2,033
฿3,191 total
includes taxes & fees
10 Oct - 11 Oct
Le Camere Luxsury Rooms
Exterior

20. Populus

Populus
1.0 star property
Santa Lucia
7.8 out of 10, Good, (75 reviews)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is ฿2,535
฿2,890 total
includes taxes & fees
19 Sept - 20 Sept
Populus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
View from room
Calafatari B&B
3.0 star property
9.8
Exceptional
17 reviews
View
Suite, Balcony, Sea View
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
Classic Room | View from room
Gymnasium
3.0 star property
8.8
Excellent
42 reviews
View
Porch
Piccolo Hotel Casa Mia
3.0 star property
8.6
Excellent
386 reviews
View
Room
Re Dionisio Luxury Suites
3.0 star property
8.8
Excellent
58 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Teatro dei Pupi or Cathedral of Syracuse.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Fortaleza Charme House

Fortaleza Charme House

10/10 Excellent
"Incredible hotel. Francesco was extremely helpful. An ideal location, just across the bridge from the Old City (Ortigia) so it's an easy walk without the hassle. And, if you're driving there is parking nearby. Definitely on the list of hotels to stay again."
John 1-night trip
Posted 22 hours ago
Fortaleza Charme House

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Nostos rooms & Apartments and Caportigia Boutique Hotel.
How many hotels will I find in Santa Lucia?
Expedia has 315 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.