A modern building with a unique triangular roof and a central spire.

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Check prices for these dates

This weekend
31 Jul - 2 Aug
Next weekend
7 Aug - 9 Aug

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Our top choices for Santa Lucia hotels

Rooftop terrace

1. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (289 reviews)
"Beautiful hotel with good amenities"
Canada
Alessia
The price is ฿6,060
฿7,049 total
includes taxes & fees
29 Jul - 30 Jul
Caportigia Boutique Hotel
Front of property

2. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (686 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is ฿4,701
฿5,360 total
includes taxes & fees
30 Jul - 31 Jul
Grande Albergo Alfeo
Coffee/tea maker, electric kettle

3. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (282 reviews)
"Room clean, air-conditioning good, beds good, staff nice. Not really sound proof, but everyone is respectful and quiet during the night. Staff isn't always at the reception, but that didn't bother us. Super central, super safe. There's no lifts though."
United Kingdom
Amanda
The price is ฿3,343
฿3,811 total
includes taxes & fees
29 Jul - 30 Jul
Nostos rooms & Apartments
Porch

4. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is ฿3,260
฿3,716 total
includes taxes & fees
4 Aug - 5 Aug
Piccolo Hotel Casa Mia
Triple Room, Balcony | Balcony

5. B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (88 reviews)
"."
United States
Dany
The price is ฿3,059
฿3,487 total
includes taxes & fees
2 Aug - 3 Aug
B&B Nike
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing

6. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"The room appeared to be recently remodeled and was very modern. Of the 4 hotels that we stayed at on this trip, the bed/pillows were the most comfortable. Great view of the marina from our room balcony and public parking (free) was relatively easy. "
United States
Michael
The price is ฿3,805
฿4,338 total
includes taxes & fees
28 Jul - 29 Jul
Lakkios
Breakfast area

7. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (130 reviews)
"Amazing stay. Beautiful views and everyone was very friendly. "
United States
Anna
The price is ฿9,167
฿10,466 total
includes taxes & fees
28 Jul - 29 Jul
Giuggiulena Villa
Lobby lounge

8. Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is ฿3,782
฿4,312 total
includes taxes & fees
2 Aug - 3 Aug
Regina Margherita
Standard Double Room, Private Bathroom | Desk, soundproofing, iron/ironing board (on request), free WiFi

9. B&B Vergilia

B&B Vergilia
3.0 star property
Santa Lucia
9.8 out of 10, Exceptional, (56 reviews)
"The host, Raymond is very friendly. He came to meet us at the Square and explained in details on every houseware."
Canada
Siu-Fai
The price is ฿3,605
฿4,109 total
includes taxes & fees
28 Jul - 29 Jul
B&B Vergilia
Suite | Soundproofing, free WiFi

10. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (43 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is ฿4,674
฿5,328 total
includes taxes & fees
3 Aug - 4 Aug
Hotel Palazzo Cavalieri
View from room

11. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (15 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is ฿6,089
฿6,941 total
includes taxes & fees
3 Aug - 4 Aug
Calafatari B&B
Double Room, 1 King Bed, Sea View, Tower | In-room safe, desk, soundproofing, iron/ironing board

12. Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.0 out of 10, Very good, (2 reviews)
"Great hotel. Close to everything 15min walk into Ortigia and the excursions dock. The staff are incredibly helpful and thoughtful. Rooms are clean and nice. The balcony had great views of the water and ortigia. Highly recommend to anyone visiting Siracusa! "
United States
Aria
The price is ฿8,965
฿10,244 total
includes taxes & fees
29 Jul - 30 Jul
Casa Miranda Boutique
Free WiFi

13. B&B L'INFIORESCENZA

B&B L'INFIORESCENZA
Santa Lucia
8.0 out of 10, Very good, (2 reviews)
"Camera pulita cuscini scomodi pareti sottilissime si sente nelle stanze intorno qualsiasi piccolissimo rumore, colazione al bar cappuccino ottimo e paste molto grandi e buone, negozi nelle vicinanze no e distanza da Ortigia 15 minuti a piedi circa."
Italy
Loris
The price is ฿1,517
฿2,166 total
includes taxes & fees
13 Aug - 14 Aug
B&B L'INFIORESCENZA
Luxury Quadruple Room, Balcony, City View | In-room safe, desk, soundproofing, iron/ironing board

14. B&B IL MORO

B&B IL MORO
Santa Lucia
The price is ฿3,034
฿4,333 total
includes taxes & fees
3 Aug - 4 Aug
B&B IL MORO
Comfort Triple Room, Balcony, Ocean View | View from room

15. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is ฿3,309
฿3,772 total
includes taxes & fees
29 Jul - 30 Jul
Hotel Mediterraneo
Double Room | Premium bedding, desk, cots/infant beds, rollaway beds

16. B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is ฿3,134
฿3,573 total
includes taxes & fees
30 Jul - 31 Jul
B&B Siracusa
Superior Triple Room, Sea View | Terrace/patio

17. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (36 reviews)
"Wonderful stay in the center of it all "
United States
lori
The price is ฿6,338
฿7,226 total
includes taxes & fees
30 Jul - 31 Jul
Fortaleza Charme House
1 bedroom, down duvets, minibar, in-room safe

18. Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Wonderful property, excellent staff and the most amazing view from the apartment"
Australia
Anthony
The price is ฿9,557
฿10,896 total
includes taxes & fees
3 Aug - 4 Aug
Re Dionisio Luxury Suites
Exterior

19. Populus

Populus
1.0 star property
Santa Lucia
7.8 out of 10, Good, (75 reviews)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is ฿3,103
฿3,538 total
includes taxes & fees
28 Jul - 29 Jul
Populus
Terrace/patio

20. Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
7.0 out of 10, Good, (2 reviews)
"Très belle chambre, mais forte odeur d’humidité, pas de FENÊTRE quartier type « cour des Miracles «  loin du centre historique, pas de supérette ou de restaurant dans le proche voisinage loin de toute commodité"
France
Philippe
The price is ฿2,414
฿3,625 total
includes taxes & fees
29 Jul - 30 Jul
Le Camere Luxsury Rooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
View from room
Calafatari B&B
3.0 star property
10.0
Exceptional
15 reviews
View
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
289 reviews
View
Suite | Soundproofing, free WiFi
Hotel Palazzo Cavalieri
4.0 star property
9.0
Wonderful
43 reviews
View
1 bedroom, down duvets, minibar, in-room safe
Re Dionisio Luxury Suites
3.0 star property
8.8
Excellent
58 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Top Santa Lucia Hotel Reviews

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"What an amazing stay at Grand Hotel Ortigia! From the spacious room, to the excellent rooftop breakfast. It was a wonderful stay! The location was superb and the private beach was a wonderful plus. I can’t wait to return one day."
Abby 4-night trip
Posted 2 days ago
Grand Hotel Ortigia Siracusa

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.
How many hotels will I find in Santa Lucia?
Expedia has 310 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.