Find hotels in Santa Cruz Mixtepec from ฿770

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14 Dec - 15 Dec
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15 Dec - 16 Dec
Next weekend
19 Dec - 21 Dec
In two weeks
26 Dec - 28 Dec

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Our top choices for Santa Cruz Mixtepec hotels

Romantic Double Room | Blackout curtains, iron/ironing board, free WiFi, bed sheets
Motel Puerta del Cielo

Motel Puerta del Cielo

Motel Puerta del Cielo
2.5 star property
San Agustín de las Juntas
8.6 out of 10, Excellent, (4)
This welcoming motel offers 24-hour front desk service and room service near the historic Zócalo and Church of Santo Domingo de Guzmán. San Juan de Dios market is nearby, with easy access to Oaxaca International Airport.
"Good "
United States
Manuel
The price is ฿2,189
฿2,605 total
includes taxes & fees
15 Dec - 16 Dec
Motel Puerta del Cielo
Living area
LA PATRONA HOSTAL

LA PATRONA HOSTAL

LA PATRONA HOSTAL
2.0 star property
Santa Cruz Xoxocotlán
10.0 out of 10, Exceptional, (1)
LA PATRONA HOSTAL
Terrace/patio
Villas Horizonte Oaxaca

Villas Horizonte Oaxaca

Villas Horizonte Oaxaca
3.0 star property
Santa María Coyotepec
6.8 out of 10, (3)
Located within a 15-minute drive of Zócalo and Church of Santo Domingo de Guzmán, this Oaxaca hotel offers a peaceful garden setting. Enjoy a drink at the bar, grab a snack at the deli, or visit the café while using free WiFi and parking.
"Rooms are nice and clean, they gave me a room without air conditioned but I told them I booked a room with AC and they gave me another room. The hotel is out of downtown, no noise, streets are not paved in that area. It is a good chooce If you don’t want to expend too much money. "
United States
Lourdes
The price is ฿1,340
฿1,594 total
includes taxes & fees
1 Jan - 2 Jan 2026
Villas Horizonte Oaxaca
Executive Suite, 1 King Bed | In-room safe, individually decorated, individually furnished
Maria Ines Hotel Suite

Maria Ines Hotel Suite

Maria Ines Hotel Suite
3.5 star property
San Agustín de las Juntas
9.4 out of 10, Exceptional, (388)
In the heart of Oaxaca, this hotel offers Italian cuisine at Parrillaje Italiano restaurant and rejuvenating massage treatments. Near Zócalo and Church of Santo Domingo de Guzmán, guests appreciate the helpful staff, fitness centre, and convenient airport access.
"Clean, quiet for being on a busy street"
United States
Elizabeth
Maria Ines Hotel Suite
Lobby
OYO Hotel Rey David, Oaxaca

OYO Hotel Rey David, Oaxaca

OYO Hotel Rey David, Oaxaca
2.5 star property
Ocotlán de Morelos
4.2 out of 10, (31)
"No AC, Fans, Poor Place"
United States
Javier
The price is ฿593
฿770 total
includes taxes & fees
28 Dec - 29 Dec
OYO Hotel Rey David, Oaxaca
Property entrance
Hotel Guivá Aeropuerto

Hotel Guivá Aeropuerto

Hotel Guivá Aeropuerto
3.0 star property
San Agustín de las Juntas
7.4 out of 10, Good, (32)
Just minutes from Oaxaca airport, this business-friendly hotel offers easy access to Zócalo and Church of Santo Domingo. Enjoy the rooftop terrace with city views after exploring nearby San Juan de Dios.
"Staff was friendly and helpful. Check on and out was easy and quick. Room was clean. "
United States
fernando
The price is ฿2,627
฿3,126 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Guivá Aeropuerto
Front of property – evening/night
Motel Las Maravillas

Motel Las Maravillas

Motel Las Maravillas
2.0 star property
Santa Cruz Xoxocotlán
3.0 out of 10, (4)
Just a short drive from Zócalo and San Juan de Dios, this welcoming motel offers 24-hour room service for late-night cravings. Complimentary WiFi keeps you connected while free parking adds extra value to your Oaxaca adventure.
"Dirty rooms, broken washrooms, terrible linen and towels. "
Canada
Rajan
The price is ฿2,715
฿3,231 total
includes taxes & fees
15 Dec - 16 Dec
Motel Las Maravillas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Mixtepec Hotel Reviews

Villas Horizonte Oaxaca

Villas Horizonte Oaxaca

8/10 Good
"Rooms are nice and clean, they gave me a room without air conditioned but I told them I booked a room with AC and they gave me another room. The hotel is out of downtown, no noise, streets are not paved in that area. It is a good chooce If you don’t want to expend too much money. "
Lourdes 1-night trip
Posted 9 months ago
Villas Horizonte Oaxaca

More cheap stays in Santa Cruz Mixtepec

OYO Hotel Rey David, Oaxaca

OYO Hotel Rey David, Oaxaca

16 de Septiembre 248 Ocotlán de Morelos OAX
The price is ฿593 per night from 28 Dec to 29 Dec
฿593
฿770 total
28 Dec - 29 Dec
includes taxes & fees
4/10 (31 reviews)

Frequently asked questions

What's the best place to stay in Santa Cruz Mixtepec?
Maria Ines Hotel Suite, located 19.6 mi (31.5 km) from the heart of Santa Cruz Mixtepec, is a top choice for your stay, based on our traveller data. Two other choices for your trip to the area are OYO Hotel Rey David, Oaxaca and Hotel Guivá Aeropuerto. See all available top hotels, or vacation rentals in Santa Cruz Mixtepec.
What are some of the best holiday rentals that Santa Cruz Mixtepec has to offer?
Casa MaryFer: This holiday home rental outside Santa Cruz Mixtepec offers a terrace, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, an oven and a microwave. See all vacation rentals in Santa Cruz Mixtepec.
If I need to cancel my hotel reservation in Santa Cruz Mixtepec, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz Mixtepec.
What's it like to stay in Santa Cruz Mixtepec?
Visitors will definitely enjoy all that Santa Cruz Mixtepec has to offer. There are 33 hotels and other accommodation options in the surrounding area. Find out more about Santa Cruz Mixtepec.
What are the top places to visit in Santa Cruz Mixtepec?
Places to visit in the wider area include Convento de Cuilapam, Dona Rosa Studio and Workshop of Jacobo and Maria Angeles. Take a look at what more there is to see and do in Expedia's Santa Cruz Mixtepec guide.
What's the weather like in Santa Cruz Mixtepec?
The hottest months are usually April and May, with an average temperature of 19°C, while the coldest months are January and December, with an average of 16°C. The rainiest months in Santa Cruz Mixtepec are September, June, August and July, with each month seeing an average of 237 mm of rainfall.

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