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Check prices for these dates

Tonight
16 Dec - 17 Dec
Tomorrow
17 Dec - 18 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Santa Croce hotels

Indoor pool
Casual Rinascimento Firenze Hotel

Casual Rinascimento Firenze Hotel

Casual Rinascimento Firenze Hotel
3.0 star property
Santa Croce
9.2 out of 10, Wonderful, (272)
"We enjoyed our stay very much!"
Germany
Thomas
The price is ฿3,636
฿4,444 total
includes taxes & fees
23 Dec - 24 Dec
Casual Rinascimento Firenze Hotel
Family Triple Room | Premium bedding, minibar, in-room safe, soundproofing
Residenza La Musa Amarcord

Residenza La Musa Amarcord

Residenza La Musa Amarcord
Santa Croce
9.8 out of 10, Exceptional, (150)
"We liked our stay at this property. It’s a good value for the location, size, and style of the hotel. The staff was also very helpful and polite. I would stay here, again. "
United States
Fernando
Residenza La Musa Amarcord
Seasonal outdoor pool
Plaza Hotel Lucchesi

Plaza Hotel Lucchesi

Plaza Hotel Lucchesi
4.0 star property
Santa Croce
9.4 out of 10, Exceptional, (1003)
"Clean and amazing staff."
United States
Marcos
The price is ฿6,727
฿7,918 total
includes taxes & fees
7 Jan - 8 Jan 2026
Plaza Hotel Lucchesi
View from room
LHP Hotel River & SPA

LHP Hotel River & SPA

LHP Hotel River & SPA
5.0 star property
Santa Croce
8.8 out of 10, Excellent, (247)
"The rooms were clean and the staff was very friendly. Breakfast had a great variety of food to choose from and the staff was wonderful!"
United States
Jeremy and Linda
LHP Hotel River & SPA
Lobby lounge
La Maison du Sage

La Maison du Sage

La Maison du Sage
Santa Croce
9.6 out of 10, Exceptional, (352)
"Room spacious, bed was very comfortable. Room was decorated beautifully. Spotless. Great location."
United States
Karen
La Maison du Sage
Deluxe Double or Twin Room, Balcony, River View | Premium bedding, minibar, in-room safe, soundproofing
Hotel Balestri

Hotel Balestri

Hotel Balestri
4.0 star property
Santa Croce
9.2 out of 10, Wonderful, (1003)
"Everything was fantastic - clean, modern rooms, great shower, friendly staff, awesome breakfast, great location. "
United States
Christopher
The price is ฿5,387
฿6,444 total
includes taxes & fees
18 Dec - 19 Dec
Hotel Balestri
Restaurant
Eurostars Florence Boutique

Eurostars Florence Boutique

Eurostars Florence Boutique
4.0 star property
Santa Croce
8.6 out of 10, Excellent, (480)
"The room was clean and the staff very accommodating. The breakfast was quite sufficient and had a good variety. The location is great. It's a short walk from the square, shopping and from restaurants. "
Canada
Ester
The price is ฿2,636
฿3,419 total
includes taxes & fees
16 Jan - 17 Jan 2026
Eurostars Florence Boutique
Interior
Wine Apartments Florence Ansonica

Wine Apartments Florence Ansonica

Wine Apartments Florence Ansonica
Santa Croce
8.6 out of 10, Excellent, (4)
"Pros: Exactly like the pictures. Friendly and responsive staff. Everything works. Washer in apartment. Market nearby. Cons: bed bugs (totally unacceptable!), noisy district, drunks roaming streeets."
Canada
Robert
Wine Apartments Florence Ansonica
Lobby
FH55 Grand Hotel Mediterraneo

FH55 Grand Hotel Mediterraneo

FH55 Grand Hotel Mediterraneo
4.0 star property
Santa Croce
8.0 out of 10, Very good, (967)
"Very good"
United States
Kami
FH55 Grand Hotel Mediterraneo
Panoramic Suite, Jetted Tub | Terrace/patio
Hotel Orcagna

Hotel Orcagna

Hotel Orcagna
2.0 star property
Santa Croce
9.2 out of 10, Wonderful, (664)
"We stayed in the family suite which was spacious and clean. We had a rooftop view of the Duomo and our own hot tub and terrace. Breakfast was fabulous and hearty, exactly what we needed for sightseeing all day. I highly recommend staying at Hotel Orcagna and would stay there again! "
United States
Stephanie
The price is ฿2,660
฿3,259 total
includes taxes & fees
19 Dec - 20 Dec
Hotel Orcagna
Garden
Maison Santa Croce

Maison Santa Croce

Maison Santa Croce
Santa Croce
9.8 out of 10, Exceptional, (41)
"A nice place to stay."
United States
Randy
The price is ฿4,141
฿4,999 total
includes taxes & fees
22 Dec - 23 Dec
Maison Santa Croce
Restaurant
Hotel Bodoni

Hotel Bodoni

Hotel Bodoni
2.0 star property
Santa Croce
8.2 out of 10, Very good, (792)
"Nice people and convenient location!!!!"
United States
julio
The price is ฿2,364
฿2,933 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Bodoni
Interior detail
Nove Guest House

Nove Guest House

Nove Guest House
Santa Croce
10.0 out of 10, Exceptional, (32)
"Place was perfect"
United States
Patricia
The price is ฿2,515
฿3,211 total
includes taxes & fees
18 Dec - 19 Dec
Nove Guest House
Private spa tub
LHP River Club

LHP River Club

LHP River Club
5.0 star property
Santa Croce
9.4 out of 10, Exceptional, (23)
"perfect for our needs"
United States
Meagan
The price is ฿4,360
฿5,388 total
includes taxes & fees
17 Dec - 18 Dec
LHP River Club
Premium bedding, in-room safe, free cots/infant beds, free WiFi
Aurum Uffizi

Aurum Uffizi

Aurum Uffizi
4.0 star property
Santa Croce
7.6 out of 10, Good, (1004)
"Great Locations walkable to all the placese."
Canada
Sam
The price is ฿5,993
฿7,111 total
includes taxes & fees
18 Dec - 19 Dec
Aurum Uffizi
Interior
Mamo Florence - Dante & Virgilio Apartments

Mamo Florence - Dante & Virgilio Apartments

Mamo Florence - Dante & Virgilio Apartments
Santa Croce
10.0 out of 10, Exceptional, (8)
"Great little 2 bedroom apartment for our family. Very convenient and nice area. "
Australia
Doan
The price is ฿2,684
฿7,101 total
includes taxes & fees
17 Dec - 18 Dec
Mamo Florence - Dante & Virgilio Apartments
Family Suite, River View | Premium bedding, down duvets, memory-foam beds, free minibar
Le Rêve De Naim - Firenze

Le Rêve De Naim - Firenze

Le Rêve De Naim - Firenze
Santa Croce
9.6 out of 10, Exceptional, (16)
"Clean, great staff, rooms are spacious and beautiful "
Canada
Nicole
The price is ฿7,485
฿8,678 total
includes taxes & fees
8 Jan - 9 Jan 2026
Le Rêve De Naim - Firenze
Exterior detail
Elevator, Ac, Wifi - Heart of historic city center

Elevator, Ac, Wifi - Heart of historic city center

Elevator, Ac, Wifi - Heart of historic city center
Santa Croce
7.0 out of 10, Good, (4)
"Is very good and very well centric for wherever you go!! Thanks to the people who are in charge!!"
United States
Jesus
Elevator, Ac, Wifi - Heart of historic city center
Junior Suite, Garden View | Down duvets, in-room safe, individually decorated, desk
FH55 Med Guesthouse

FH55 Med Guesthouse

FH55 Med Guesthouse
Santa Croce
9.0 out of 10, Wonderful, (6)
"Good place, very clean and cozy. Far from the train station and the center of the action."
Canada
Eric
The price is ฿3,303
฿4,078 total
includes taxes & fees
19 Dec - 20 Dec
FH55 Med Guesthouse
Exterior
Residenza D'Epoca Historia Luxury

Residenza D'Epoca Historia Luxury

Residenza D'Epoca Historia Luxury
Santa Croce
7.8 out of 10, Good, (141)
"Very enjoyable staff. Great location. Great staff. Office Open til 6pm. "
Canada
Wayne
The price is ฿1,896
฿2,530 total
includes taxes & fees
17 Dec - 18 Dec
Residenza D'Epoca Historia Luxury
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Croce

Find the best Santa Croce areas for the activities you enjoy most.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Via de' Calzaiuoli or Giotto's Campanile while you're exploring the neighbourhood.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Oltrarno

Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Via Maggio while you're exploring the neighbourhood.

Top Santa Croce Hotel Reviews

FH55 Grand Hotel Mediterraneo

FH55 Grand Hotel Mediterraneo

10/10 Excellent
"Very good"
Kami 2-night trip
Posted 9 days ago
FH55 Grand Hotel Mediterraneo

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Frequently asked questions

What is Santa Croce like?
Santa Croce is an historic neighbourhood known for its top museums. Make sure that you visit Basilica of Santa Croce and Piazza Santa Croce as part of your Santa Croce travel plans.
What's a favourite hotel to stay in Santa Croce?
Based on Expedia customer reviews, Residenza La Musa Amarcord is the highest ranked property in Santa Croce. This affittacamere is a short 5-minute walk from Uffizi Gallery, and it offers free WiFi and flat-screen TVs. Other favourite options in the area include Peruzzi Urban Residences and B&B San Remigio Firenze.
How many hotels are there in the Santa Croce area?
If you're searching for places to stay in Lungarno del Tempio, Expedia has something to meet your needs with 830 Santa Croce hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Santa Croce, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Santa Croce.
What are the top things to see and do in Santa Croce?
For cultural attractions in Santa Croce, head to I Mosaici Di Lastrucci, Casa Buonarroti and Teatro Verdi. Basilica of Santa Croce and Piazza Santa Croce are also a couple of places to visit in the neighbourhood. A few places to visit in the area around Santa Croce include Mercato di Sant'Ambrogio, Galleria d'Arte Civico69 and Museo dell'Opera di Santa Croce. While you're out sightseeing, National Central Library of Florence and Casa Siviero Museum are a couple of additional sights to visit in Lungarno del Tempio.