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Our top choices for Santa Ana LGBT-friendly hotels

Holiday Inn Santa Ana Orange County Airport by IHG

Holiday Inn Santa Ana Orange County Airport by IHG
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (1127)
"We had a great stay"
United States
amin Aghaie
The price is ฿2,536
฿2,871 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Santa Ana Orange County Airport by IHG

Hotel Zessa Orange County Airport, a DoubleTree by Hilton

Hotel Zessa Orange County Airport, a DoubleTree by Hilton
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (573)
"Great place!"
United States
Sintia
The price is ฿2,962
฿3,347 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Zessa Orange County Airport, a DoubleTree by Hilton

La Quinta Inn & Suites by Wyndham Orange County Airport

La Quinta Inn & Suites by Wyndham Orange County Airport
3.0 star property
Santa Ana
7.8 out of 10, Good, (2020)
"My family and I enjoyed our stay. Would book again."
United States
Latausha
The price is ฿3,262
฿3,686 total
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Orange County Airport

Sonesta Simply Suites Orange County Airport

Sonesta Simply Suites Orange County Airport
2.0 star property
Santa Ana
7.4 out of 10, Good, (1003)
"Clean and great staff "
United States
stephanie Lee
The price is ฿2,921
฿3,306 total
includes taxes & fees
11 Jan - 12 Jan 2026
Sonesta Simply Suites Orange County Airport

Comfort Inn & Suites Orange County John Wayne Airport

Comfort Inn & Suites Orange County John Wayne Airport
2.5 star property
Santa Ana
8.0 out of 10, Very good, (1004)
"The room was great. The bed was comfortable, the breakfast was delicious and the staff was friendly. I would definitely stay here again!"
United States
Wilfrido
The price is ฿2,957
฿3,347 total
includes taxes & fees
29 Dec - 30 Dec
Comfort Inn & Suites Orange County John Wayne Airport

Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Holiday Inn Express & Suites Santa Ana - Orange County by IHG
2.5 star property
Lyon Street
8.6 out of 10, Excellent, (1226)
"enjoyed our stay."
United States
Melissa
The price is ฿3,738
฿4,231 total
includes taxes & fees
24 Dec - 25 Dec
Holiday Inn Express & Suites Santa Ana - Orange County by IHG

Courtyard by Marriott Santa Ana Orange County

Courtyard by Marriott Santa Ana Orange County
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (1001)
"The staff and hotel were fantastic and it was very quiet during my stay"
United States
JAMES
The price is ฿3,646
฿4,128 total
includes taxes & fees
26 Dec - 27 Dec
Courtyard by Marriott Santa Ana Orange County

Orange County Hotel

Orange County Hotel
3.5 star property
Santa Ana
7.2 out of 10, Good, (1004)
"Nice place, good rate, nice staff."
United States
Chad
The price is ฿3,518
฿3,982 total
includes taxes & fees
28 Dec - 29 Dec
Orange County Hotel

City Express by Marriott Santa Ana/Orange County Airport

City Express by Marriott Santa Ana/Orange County Airport
2.5 star property
Santa Ana
7.2 out of 10, Good, (1000)
"O have a great time everything was great thanks I back again "
United States
Silvia
The price is ฿3,505
฿3,968 total
includes taxes & fees
2 Jan - 3 Jan 2026
City Express by Marriott Santa Ana/Orange County Airport

Courtyard by Marriott Costa Mesa South Coast Metro

Courtyard by Marriott Costa Mesa South Coast Metro
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (1001)
"Clean room, safe / nice area, walkable restaurants and close to the observatory. Easy check in, great staff 10/10 "
United States
River
The price is ฿3,423
฿3,889 total
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott Costa Mesa South Coast Metro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santa Ana Hotel Reviews

Frequently asked questions

Looking for a gay-friendly hotel in Santa Ana?
Consider this your open invitation to pack your bags and find Santa Ana hotels that are members of the International Gay & Lesbian Travel Association on Expedia. Staying in this family-friendly area will give you access to its shops and theme parks.
What is the top LGBTQ-friendly hotel in Santa Ana?
Holiday Inn Santa Ana Orange County Airport by IHG is a top LGBTQ-friendly hotel that features free Wi-Fi and a 24-hour business centre. Hotel Zessa Orange County Airport, a DoubleTree by Hilton and La Quinta Inn & Suites by Wyndham Orange County Airport are two other good choices for your trip.
How many gay-friendly accommodation options are there in Santa Ana?
You'll find 11 gay-friendly accommodation options in Santa Ana.
What should I do while I'm visiting Santa Ana?
During your trip, get out and enjoy everything Santa Ana has to offer. You and your travelling companions may want to visit Old Orange County Courthouse, Bowers Museum and Santa Ana Zoo. While you're here, create some great memories of your trip with stops at Discovery Science Center, Heritage Museum of Orange County and The Observatory.
What is an LGBTQ-friendly hotel in Santa Ana?
LGBTQ-friendly hotels, also known as gay-friendly hotels, welcome all travellers who identify as LGBTQIA+. Expedia has compiled a selection of LGBTQ-friendly hotels worldwide. In Santa Ana, these hotels operate in a spirit of inclusiveness, prioritising a diverse environment in which guests are welcomed, respected and not obliged to declare or hide their sexual orientation.
What can I expect from a gay-friendly hotel in Santa Ana?
Stay at a gay-friendly hotel in Santa Ana and the staff will help you explore the local gay scene and the LGBTQ+ culture. Many of our LGBTQ-friendly accommodation options offer community-specific packages, exclusive tours and opportunities for social interaction.