Saint Matthews Holiday Rentals, South Carolina: Private House Rentals

A swamp with tall trees and water reflecting the greenery.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Saint Matthews

Pet friendly

Apartment

Pool

Family friendly

Condo

Cottage

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Saint Matthews hotels

A self-service kiosk with a beverage cooler, microwave, and various food items.

A modern interior with a dining area, seating arrangements, and a reception desk.

A modern hotel lobby with a reception desk, blue and gray seating, a TV screen, and unique pendant lighting.

A breakfast counter with a sign reading 'TOP IT BREAKFAST,' a coffee machine, a yogurt dispenser, and various food items.

1. Tru by Hilton Orangeburg

Orangeburg

Matthew

฿3,677

฿4,081 total

includes taxes & fees

1 Nov - 2 Nov

A lobby with a reception desk, a sofa, a coffee station, and a flag.

A modern hotel lobby with a green ceiling, a grey sofa, a patterned ottoman, a wooden bench, and a chair with a geometric throw.

A hotel room with a large bed, a desk, a chair, a nightstand, and a wall-mounted lamp.

A modern restaurant with a counter, seating area, and a food display.

2. Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

Jenelyn

฿3,822

฿4,243 total

includes taxes & fees

9 Nov - 10 Nov

A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

A hotel room with a large bed, a desk with a flat-screen TV, a chair, a desk lamp, and a window with curtains.

A modern dining area with tables and chairs, large windows with sheer curtains, and pendant lighting.

A gym with treadmills, a bench, and a ball.

3. Hampton Inn & Suites Orangeburg

Orangeburg

sonia

฿4,532

฿5,031 total

includes taxes & fees

25 Oct - 26 Oct

A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

An outdoor patio area with a fire pit, seating, and tables.

A hotel room with two beds, a seating area, and a large abstract painting on the wall.

A modern hotel room with a grey sofa, a flat-screen TV, a desk with a lamp, and abstract wall art.

4. SpringHill Suites by Marriott Orangeburg

Orangeburg

Henrietta

฿3,659

฿4,062 total

includes taxes & fees

19 Oct - 20 Oct

A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

A modern indoor swimming pool with clear glass walls, sunlit lounge areas, and a view of greenery outside.

A lobby with a reception desk, a staircase, and seating area with orange chairs.

A modern kitchen with a wooden table and bench, blue cabinets, and a yellow pendant light fixture.

5. Spark by Hilton Orangeburg

Orangeburg

TaNikka

฿3,272

฿3,632 total

includes taxes & fees

15 Oct - 16 Oct

A hotel room with two beds, a desk, and a chair. There are wall-mounted lamps and a large window with curtains.

A reception area with a wooden reception desk, a wall-mounted clock, and a welcome mat.

A restaurant with multiple tables and chairs, a wooden counter, and a painting on the wall.

A Comfort Inn & Suites hotel with a brick facade, multiple windows, and a clear blue sky.

6. Comfort Inn & Suites Orangeburg

Orangeburg

LINA

฿3,392

฿3,765 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a sofa, chairs, a coffee table, and a staircase with a green leaf-patterned wall.

A reception area with a staircase, reception desk, and seating area with blue sofas.

A hotel room with a bed, bedside tables, a nightstand, a lamp, a wall-mounted phone, a painting, a window with curtains, and an air conditioning unit.

A dining area with wooden tables and chairs, a large window with a view, a flat-screen TV, and a vending machine.

7. Sleep Inn Orangeburg

Orangeburg

Dereck

฿2,957

฿3,283 total

includes taxes & fees

25 Oct - 26 Oct

A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

A workspace with two desks, each with a computer monitor, keyboard, and chair.

A reception area with a wooden reception desk, a welcome mat, a vending machine, and a clock on the wall.

A corner market with a refrigerator stocked with beverages and snacks.

8. Fairfield Inn by Marriott Orangeburg

Orangeburg

Julie

฿3,392

฿3,765 total

includes taxes & fees

1 Nov - 2 Nov

A breakfast bar with pastries, fruits, and a vase with flowers.

A Travelodge motel with a parking lot and a signboard.

A reception area with a dark-colored reception desk, a clock on the wall, and a doormat with "Travelodge" written on it.

A hotel room with two beds, a nightstand, and two wall-mounted lamps.

9. Travelodge by Wyndham Orangeburg

Orangeburg

Beth

฿1,962

฿2,177 total

includes taxes & fees

13 Oct - 14 Oct

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A spacious lobby with a central round table and chairs, a bar area, and a staircase leading to an upper level.

A spacious dining area with a kitchen in the background, featuring a modern design with a ceiling fan, a clock, and a flat-screen TV mounted on the wall.

A pool area with lounge chairs and a building in the background.

10. Quality Inn & Suites Orangeburg

Orangeburg

Angela

฿1,599

฿1,775 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with a long counter, equipped with coffee makers, a kettle, and a microwave.

A hotel room with a desk, a chair, a flat-screen TV, a refrigerator, a microwave, a lamp, and a large mirror.

A hotel room with a beige armchair, a black ottoman, a standing lamp, and an air conditioning unit.

A multi-story hotel with a covered entrance, balconies, and a parking area.

11. Super 8 by Wyndham, Orangeburg

Orangeburg

Melissa

฿1,962

฿2,177 total

includes taxes & fees

13 Oct - 14 Oct

A hotel room with a bed, a desk, a chair, a sofa, and a table.

A breakfast corner with wooden tables and chairs, a coffee machine, and a sign indicating breakfast hours.

A hotel with a swimming pool, outdoor seating, and a flagpole with an American flag.

A gym with cardio equipment, dumbbells, and a TV on a shelf.

12. Baymont by Wyndham Orangeburg North

Orangeburg

Brandon

฿1,853

฿2,056 total

includes taxes & fees

19 Oct - 20 Oct

A patio area with wicker furniture, a stone fire pit, and outdoor seating.

A modern living room with a stone wall, a flat-screen TV, a fireplace, and a dining area with a round table and chairs.

A multi-story hotel with a prominent sign, a covered entrance, and a parking lot.

A modern restaurant with a central island, multiple seating areas, and a large window providing natural light.

13. Fairfield Inn & Suites by Marriott Santee

Santee

Melissa

฿4,647

฿5,158 total

includes taxes & fees

18 Oct - 19 Oct

A reception desk with a flat-screen TV, a Dell computer, and a door.

A hotel reception area with a counter, coffee machines, and a refrigerator.

A two-story building with a grey facade, large windows, and a covered entrance area.

A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

14. Red Roof Inn Orangeburg

Orangeburg

phyllis

฿1,901

฿2,110 total

includes taxes & fees

19 Oct - 20 Oct

A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

A Hampton Inn hotel at night with a well-lit facade and a parking lot in the foreground.

A gym with treadmills, weight machines, and a wall of dumbbells.

A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.

15. Hampton Inn Santee-I-95

Santee

sandra

฿3,950

฿4,384 total

includes taxes & fees

18 Oct - 19 Oct

A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

A modern lobby with a blue sofa, teal chairs, and a wooden table.

A modern hotel lobby with a central reception desk, a children's play area, and a restaurant named "Top It Break."

A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.

16. Tru By Hilton Santee

Santee

Connor

฿3,392

฿3,765 total

includes taxes & fees

18 Oct - 19 Oct

A restaurant with round tables and chairs, a counter with a display case, and large windows.

A reception desk with a laptop, a patterned sofa, and a doormat with "SOUTHERN" visible.

A hotel room with two beds, a desk, and a mirror.

A Southern Lodge building with a covered parking area, brick facade, and signage.

17. Southern Lodge 601

Orangeburg

Dorothy

฿2,516

฿2,793 total

includes taxes & fees

13 Oct - 14 Oct

A hotel entrance with a sign reading "Best Western PLISS."

A spacious living room with a large window, a ceiling fan, and a vibrant red accent wall.

A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.

A hotel room with two large beds, a wooden headboard, bedside tables with lamps, a wardrobe, and a view of the outdoors through a window.

18. Best Western Plus Santee Inn

Santee

Johnny

฿4,661

฿5,173 total

includes taxes & fees

13 Oct - 14 Oct

A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

A Baymont by Wyndham hotel with a blue and yellow facade, a covered parking area, and a large parking lot.

A spacious dining area with multiple tables and chairs, large windows, and a patterned carpet.

A hotel corridor with blue doors, a covered walkway, and a parking lot in the background.

19. Baymont by Wyndham Santee

Santee

Cindy

฿2,682

฿2,977 total

includes taxes & fees

13 Oct - 14 Oct

A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.

A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.

A room with a black console table displaying coffee and tea options, a large window, and a sliding glass door leading to a dining area with red chairs.

A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.

20. Comfort Inn & Suites Santee

Santee

santa

฿3,467

฿3,848 total

includes taxes & fees

8 Nov - 9 Nov

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Learn more about Saint Matthews

Discover small-town charm at the Calhoun County Museum, where local history comes alive through fascinating exhibits. Enjoy peaceful picnics at the town park or visit nearby Congaree National Park for remarkable hiking trails through ancient bottomland hardwood forest.

See all hotels in Saint Matthews

Top Saint Matthews Hotel Reviews

Hotel Trundle

10/10 Excellent

"This is my favorite hotel to book in Columbia. The beds are soft and the breakfast is full and delicious!"

Fairfield Inn & Suites by Marriott Columbia Downtown

8/10 Good

"The staff was really nice and welcoming. Not sure if the vents were cleaned because me and my guest were sneezing a lot when in the bathroom. Other than that the stay was good"

Country Inn & Suites by Radisson, Columbia, SC

10/10 Excellent

"Very clean, friendly staff and very good bkf. We would stay again"

Courtyard by Marriott Columbia Downtown at USC

8/10 Good

"Breakfast is available at a separate cost"

Hyatt Place Columbia/Downtown/The Vista

10/10 Excellent

"Location was convenient. Hotel was very clean and the staff was not only helpful but very friendly."

Tru By Hilton Santee

8/10 Good

"Clean Room. Newer Property."

Baymont by Wyndham Columbia Fort Jackson

10/10 Excellent

"Rooms had coaches, honestly not clean at all , bath tub , toilet and beds not clean walls and everything, it works for a couple of days but after that find a different one , elevator not up to date since 2022 , and “ breakfast “ was only cereal anda couple of other things"

Hampton Inn & Suites Columbia/Southeast-Ft. Jackson

10/10 Excellent

"It was very nice to walk into a clean room at 4am in the morning after a seventeen hour drive."

More cheap stays in Saint Matthews

Motel 6 West Columbia, SC - Airport

650 Cherokee Lane West Columbia SC

฿2,095

฿2,262 total

15 Oct - 16 Oct

includes taxes & fees

Quality Inn Columbia Airport

2516 Augusta Rd West Columbia SC

฿2,109

฿2,277 total

10 Nov - 11 Nov

includes taxes & fees

Country Inn & Suites by Radisson, Columbia, SC

220 E Exchange Blvd Columbia SC

฿2,537

฿2,841 total

1 Nov - 2 Nov

includes taxes & fees

7.8/10 Good! (1,173 reviews)

Country Inn & Suites by Radisson, Columbia Airport, SC

2245 Airport Blvd Cayce SC

฿3,335

฿3,701 total

8 Nov - 9 Nov

includes taxes & fees

Tru By Hilton Columbia Downtown

400 Gervais Street Columbia SC

฿3,352

฿3,754 total

1 Nov - 2 Nov

includes taxes & fees

Tru By Hilton Santee

263 Britain St. and 273 Britain St. Santee SC

฿3,392

฿3,765 total

18 Oct - 19 Oct

includes taxes & fees

9.2/10 Wonderful! (986 reviews)

Frequently asked questions

What's the best place for a stay in Saint Matthews?

Located 27.6 mi (44.5 km) from the heart of Saint Matthews, Tru By Hilton Columbia Downtown is a top choice for your stay, based on our traveller data. Other good options for your stay in the area are La Quinta Inn by Wyndham Columbia SE / Fort Jackson and Quality Inn Columbia Airport. See all available top hotels, or vacation rentals in Saint Matthews.

If I need to cancel my hotel reservation in Saint Matthews, will I receive a refund?

Yes! You'll find that most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Saint Matthews.

What is staying in Saint Matthews like?

Those travelling to Saint Matthews will definitely enjoy the sights to see and things to do. In Saint Matthews, there are 3 hotels and other accommodation options to choose from. Find out more about Saint Matthews.

What are the top places to visit in Saint Matthews?

A favourite place to visit is Congaree National Park. You'll also find Santee State Park and Harry Hampton Visitor Center in the area. Take a look at what more there is to see and do in Expedia's Saint Matthews guide.

What's the weather like in Saint Matthews?

The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Saint Matthews is 1297 mm.

Explore a world of travel with Expedia

More ways to book

Book Hotels in Saint Matthews on Expedia.com

Find hotels in Saint Matthews, SC from ฿1,775

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Saint Matthews

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Saint Matthews hotels

1. Tru by Hilton Orangeburg

2. Holiday Inn Express & Suites Orangeburg by IHG

3. Hampton Inn & Suites Orangeburg

4. SpringHill Suites by Marriott Orangeburg

5. Spark by Hilton Orangeburg

6. Comfort Inn & Suites Orangeburg

7. Sleep Inn Orangeburg

8. Fairfield Inn by Marriott Orangeburg

9. Travelodge by Wyndham Orangeburg

10. Quality Inn & Suites Orangeburg

11. Super 8 by Wyndham, Orangeburg

12. Baymont by Wyndham Orangeburg North

13. Fairfield Inn & Suites by Marriott Santee

14. Red Roof Inn Orangeburg

15. Hampton Inn Santee-I-95

16. Tru By Hilton Santee

17. Southern Lodge 601

18. Best Western Plus Santee Inn

19. Baymont by Wyndham Santee

20. Comfort Inn & Suites Santee

Learn more about Saint Matthews

Top Saint Matthews Hotel Reviews

Hotel Trundle

Fairfield Inn & Suites by Marriott Columbia Downtown

Country Inn & Suites by Radisson, Columbia, SC

Courtyard by Marriott Columbia Downtown at USC

Hyatt Place Columbia/Downtown/The Vista

Tru By Hilton Santee

Baymont by Wyndham Columbia Fort Jackson

Hampton Inn & Suites Columbia/Southeast-Ft. Jackson

More cheap stays in Saint Matthews

Motel 6 West Columbia, SC - Airport

Quality Inn Columbia Airport

Country Inn & Suites by Radisson, Columbia, SC

Country Inn & Suites by Radisson, Columbia Airport, SC

Tru By Hilton Columbia Downtown

Tru By Hilton Santee

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app