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Check availability on Mission District Gay-Friendly Hotels

This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Mission District LGBT-friendly hotels

A hallway with a wooden ceiling, a table with chairs, a potted plant, and framed pictures on the walls.

1. 1906 Mission

1906 Mission
2.0 star property
Mission District
7.8 out of 10, Good, (213 reviews)
"It was educational..."
United States
Arianne
The price is ฿3,065
฿3,565 total
includes taxes & fees
5 Nov - 6 Nov
1906 Mission
A spacious lobby with large windows, a seating area with a sofa and chairs, and a counter with a coffee station.

2. LUMA Hotel San Francisco

LUMA Hotel San Francisco
4.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (2,639 reviews)
"Great hotel"
United States
Farukh
The price is ฿8,283
฿9,748 total
includes taxes & fees
6 Nov - 7 Nov
LUMA Hotel San Francisco
A corner with a white bench, a large potted plant, and a coffee machine on a shelf.

3. Edwardian Hotel

Edwardian Hotel
2.0 star property
Civic Center
7.6 out of 10, Good, (446 reviews)
"I like the location, I didn’t like the size of the room, no tables no closet etc"
United States
Antonio
The price is ฿2,147
฿2,498 total
includes taxes & fees
25 Oct - 26 Oct
Edwardian Hotel
A modern building facade with vertical wooden slats, a glass entrance, and a sign reading "La Société Bar & Cafe".

4. Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA
4.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,294 reviews)
"Great location and great hotel"
United States
Sonia
The price is ฿5,412
฿7,711 total
includes taxes & fees
30 Oct - 31 Oct
Hyatt Regency San Francisco Downtown SOMA
A hotel with a modern design, featuring a prominent 'PARC 55' sign, a 'Barbary Coach' restaurant, and a view of the street with light trails from moving vehicles.

5. Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel
4.0 star property
Union Square
8.8 out of 10, Excellent, (1,675 reviews)
"Really great area to stay!"
United States
Janet
The price is ฿4,934
฿5,807 total
includes taxes & fees
6 Nov - 7 Nov
Parc 55 San Francisco - A Hilton Hotel
A rooftop pool area with blue seating and a pool.

6. Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
Downtown San Francisco
9.0 out of 10, Wonderful, (6,378 reviews)
"Clean room Staff great Amazing location"
United States
John
The price is ฿5,119
฿6,025 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Golden Gateway by IHG
A modern hotel lobby with a seating area, a bar, and large windows.

7. Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
Fisherman's Wharf
9.0 out of 10, Wonderful, (7,713 reviews)
"Great stay an breakfast"
United States
Troy
The price is ฿4,117
฿6,230 total
includes taxes & fees
4 Nov - 5 Nov
Hotel Riu Plaza Fisherman's Wharf
A dining area with a round table, white chairs, a bench, and a vase with flowers.

8. Hayes Valley Inn

Hayes Valley Inn
2.0 star property
Western Addition
8.0 out of 10, Very good, (356 reviews)
"Staff was wonderful."
United States
Mary
The price is ฿2,294
฿2,669 total
includes taxes & fees
25 Oct - 26 Oct
Hayes Valley Inn
A modern interior with a fireplace, sofas, a coffee table, and a bookshelf.

9. Grand Hyatt San Francisco

Grand Hyatt San Francisco
4.0 star property
Union Square
9.0 out of 10, Wonderful, (1,015 reviews)
"Good stay, neat and clean . would love to stay here again."
United States
Ramakant
The price is ฿4,706
฿7,122 total
includes taxes & fees
6 Nov - 7 Nov
Grand Hyatt San Francisco
A buffet area with a variety of food items and condiments.

10. citizenM San Francisco Union Square

citizenM San Francisco Union Square
4.0 star property
Union Square
9.4 out of 10, Exceptional, (1,467 reviews)
"Very welcoming and kind staff"
United States
Cynthia
The price is ฿4,075
฿4,796 total
includes taxes & fees
30 Oct - 31 Oct
citizenM San Francisco Union Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mission District Hotel Reviews

Hyatt Regency San Francisco

Hyatt Regency San Francisco

8/10 Good
"The lift is perpetually down. If not it does not work normally. I have experienced it stopping on every floor as well as taking the cargo lift from the back door!"
Jenny 3-night trip
Posted 15 hours ago
Hyatt Regency San Francisco

Frequently asked questions

Looking for an LGBTQ-friendly hotel in Mission District?
Book a place where you can be yourself! You'll find Mission District hotels that are members of the International Gay & Lesbian Travel Association on Expedia. Visitors are sure to enjoy all Mission District has to offer including its bars.
What is the top LGBTQ-friendly place to stay in Mission District?
1906 Mission is a top hotel for LGBTIQA+ guests.
What should I see while I'm in Mission District?
During your trip, get out and enjoy everything Mission District has to offer. You and your travelling companions may want to visit SOMA Pilipinas, The Chapel and Southern Exposure. While you're here, create some great memories of your trip with stops at Victoria Theatre, San Francisco Public Library and SF Armory.
What is an LGBTQ-friendly hotel in Mission District?
LGBTQ-friendly hotels are places where lesbian, gay, bisexual and transgender travellers are proudly welcomed. Expedia has compiled a selection of LGBTQ-friendly hotels worldwide. In Mission District, these hotels will provide lesbian, gay, bisexual and transgender adventurers with the information needed to design the trip of a lifetime.
What can I expect from an LGBTQ-friendly Mission District hotel?
Stay at an LGBTQ-friendly hotel in Mission District and you won't have to hide or your sexuality or your gender identity when you check in. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer community-specific packages, exclusive tours and opportunities for social interaction.