Find hotels in Mill Spring, MO from ฿2,021

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Check prices for these dates

Tonight
20 Dec - 21 Dec
Tomorrow
21 Dec - 22 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

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Our top choices for Mill Spring hotels

Lobby
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (966)
Discover peaceful stays near North Main Street Historic District. This hotel offers dual pools, free breakfast, and complimentary WiFi. After exploring nearby Margaret Harwell Art Museum, return to spacious rooms where the helpful staff ensures comfort.
"Nice room helpful staff. "
United States
Deborah
The price is ฿2,952
฿3,335 total
includes taxes & fees
25 Dec - 26 Dec
Drury Inn & Suites Poplar Bluff
Blackout curtains, free WiFi, bed sheets
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
7.8 out of 10, Good, (1001)
Enjoy a welcoming stay at this motel with free WiFi and parking near North Main Street Historic District. Staff receives praise for helpfulness, while convenient access to Margaret Harwell Art Museum enriches your Poplar Bluff experience.
"Love the updated rooms and the vending area."
United States
Kathi
The price is ฿2,387
฿2,518 total
includes taxes & fees
21 Dec - 22 Dec
Motel 6 Poplar Bluff, MO
Courtyard
Bullwinkles Rustic Lodge

Bullwinkles Rustic Lodge

Bullwinkles Rustic Lodge
2.5 star property
Poplar Bluff
8.4 out of 10, Very good, (212)
"Had to "
United States
Brenda
Bullwinkles Rustic Lodge
Lobby lounge
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (855)
"Very clean, great check in"
United States
Teresa
The price is ฿3,257
฿3,680 total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Poplar Bluff
Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (703)
Italian cuisine awaits at Castellos restaurant in this peaceful hotel. Take a refreshing swim in the indoor pool, work out in the fitness centre, or explore nearby North Main Street Historic District. Guests love the helpful staff.
"Amazing place"
United States
Mladen
The price is ฿3,455
฿3,903 total
includes taxes & fees
24 Dec - 25 Dec
Holiday Inn Poplar Bluff by IHG
Reception
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (796)
Located near North Main Street Historic District, this welcoming hotel offers an indoor pool for year-round swimming and a well-equipped fitness centre. Guests love the complimentary breakfast, free WiFi and parking. The helpful staff ensures a comfortable stay just minutes from local attractions.
"Staff was kind and provided a lot of information during check out."
United States
Shea
The price is ฿3,487
฿3,905 total
includes taxes & fees
10 Jan - 11 Jan 2026
Hampton Inn Poplar Bluff
Lobby
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
2.5 star property
Poplar Bluff
7.8 out of 10, Good, (399)
Enjoy peaceful accommodation near North Main Street Historic District with a seasonal outdoor pool and 24-hour fitness centre. Free breakfast, WiFi, and parking enhance your stay, while the helpful staff ensures comfort in clean rooms just minutes from local attractions.
"it was a nice stay, room was a little warm, thermostat may need changing out. Other than that it was great. "
United States
Jim
The price is ฿2,853
฿3,223 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn Poplar Bluff North
In-room safe, desk, free WiFi, bed sheets
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
Poplar Bluff
6.6 out of 10, (625)
Located minutes from North Main Street Historic District, this motel offers complimentary WiFi and on-the-go breakfast daily. Free parking makes it easy to visit nearby Margaret Harwell Art Museum, while the train station is just 8 minutes away.
"The lady at the front was very nice. "
United States
Travis
The price is ฿1,789
฿2,021 total
includes taxes & fees
14 Jan - 15 Jan 2026
Super 8 by Wyndham Poplar Bluff Missouri
Comfort Single Room | Individually decorated, individually furnished, blackout curtains
Current River Inn

Current River Inn

Current River Inn
3.0 star property
Van Buren
8.2 out of 10, Very good, (165)
Relax at this tranquil Van Buren motel featuring a refreshing seasonal outdoor pool. Enjoy complimentary WiFi and parking while exploring nearby Watercress Spring Camp and Picnic Grounds. Grab a quick bite at the on-site café during your Ozark adventure.
"The mattresses were fabulous. Clean rooms and friendly staff. We will stay here again. The antique store and restaurants are walking distance. Nice family friendly establishment!"
United States
Thad
The price is ฿2,907
฿3,146 total
includes taxes & fees
22 Dec - 23 Dec
Current River Inn
Family Cabin
Sam A Baker State Park

Sam A Baker State Park

Sam A Baker State Park
2.0 star property
Patterson
9.2 out of 10, Wonderful, (5)
"Pet friendly, great staff. "
United States
Charlie
The price is ฿3,929
฿4,164 total
includes taxes & fees
23 Dec - 24 Dec
Sam A Baker State Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mill Spring Hotel Reviews

Sam A Baker State Park

Sam A Baker State Park

10/10 Excellent
"We stayed two nights and we loved it. The property grounds and cabins are well maintained we will be back "
Tiffany 2-night trip
Posted 3 months ago
Sam A Baker State Park
Lake Wappapello

Lake Wappapello

10/10 Excellent
"We did loose internet connection so gps did not always help but the local stores did. Also the managers answered their phones and were so helpful in many ways! I’m very glad we went."
Dyann 2-night trip
Posted 3 months ago
Lake Wappapello

More cheap stays in Mill Spring

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2831 N Westwood Blvd Poplar Bluff MO
The price is ฿1,789 per night from 14 Jan to 15 Jan
฿1,789
฿2,021 total
14 Jan - 15 Jan 2026
includes taxes & fees
6.4/10 (623 reviews)

Frequently asked questions

Where is the best place to stay in Mill Spring?
Motel 6 Poplar Bluff, MO, located 21.9 mi (35.2 km) from the heart of Mill Spring, is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Fairfield Inn & Suites by Marriott Poplar Bluff and Holiday Inn Poplar Bluff by IHG. See all available top hotels, or vacation rentals in Mill Spring.
If I need to cancel my hotel reservation in Mill Spring, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Mill Spring.
How is it to stay in Mill Spring?
Travellers to Mill Spring will find plenty to explore and enjoy. There are 119 hotels and other accommodation options in the surrounding area. Find out more about Mill Spring.
What is there to see in Mill Spring?
A favourite place to visit is Mark Twain National Forest. You'll also find Clearwater Lake and Big Spring in the area. Take a look at what more there is to see and do in Expedia's Mill Spring guide.
What's the weather like in Mill Spring?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Mill Spring is 1321 mm.