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Check prices for these dates

Tonight
21 Mar - 22 Mar
Tomorrow
22 Mar - 23 Mar
Next weekend
27 Mar - 29 Mar
In two weeks
3 Apr - 5 Apr

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Our top choices for Main Street Hyannis hotels

Restaurant

Hyannis Travel Inn

Hyannis Travel Inn
2.5 star property
0.2 km from Main Street Hyannis
9.6 out of 10, Exceptional, (1,000 reviews)
"Great place "
United States
Shane and Jessica
The price is ฿2,565
฿2,936 total
includes taxes & fees
29 Mar - 30 Mar
Hyannis Travel Inn
Interior entrance

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1,000 reviews)
"Staff that checked me in was great"
United States
Michael
The price is ฿4,062
฿5,578 total
includes taxes & fees
22 Mar - 23 Mar
Anchor In Distinctive Waterfront Lodging
Dining

Sea Street Inn

Sea Street Inn
4.0 star property
1.5 km from Main Street Hyannis
9.8 out of 10, Exceptional, (45 reviews)
"Very nicely renovated small property with a fantastic breakfast."
United States
Paul
The price is ฿8,588
฿9,829 total
includes taxes & fees
22 Mar - 23 Mar
Sea Street Inn
Indoor pool, seasonal outdoor pool

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
1.9 km from Main Street Hyannis
9.2 out of 10, Wonderful, (119 reviews)
"Clean room, extremely comfortable beds!"
United States
Emily M
The price is ฿3,822
฿4,527 total
includes taxes & fees
26 Mar - 27 Mar
Uncommoner Hotel by Reverie Boutique Collection
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,000 reviews)
"The hotel was very clean and the accommodations exceeded out expectations."
United States
Michael
The price is ฿3,834
฿4,388 total
includes taxes & fees
29 Mar - 30 Mar
Hampton Inn & Suites Cape Cod-West Yarmouth
Indoor pool

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (495 reviews)
"Parking was free and easy, room was very clean and housekeeping service was top notch. "
United States
Maureen
The price is ฿4,720
฿5,402 total
includes taxes & fees
5 Apr - 6 Apr
Courtyard By Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,550 reviews)
"Great family friendly hotel. "
United States
Danielle
The price is ฿3,730
฿4,646 total
includes taxes & fees
24 Mar - 25 Mar
Bayside Resort Hotel
Lobby lounge

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (683 reviews)
"Rooms were clean, the beds were comfortable, and the breakfast was good. "
United States
Sheila
The price is ฿4,062
฿4,649 total
includes taxes & fees
23 Mar - 24 Mar
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
Lobby

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (20 reviews)
"It was ok staff was nice"
United States
Troy
The price is ฿3,836
฿4,391 total
includes taxes & fees
5 Apr - 6 Apr
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Exterior

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
0.9 km from Main Street Hyannis
8.4 out of 10, Very good, (894 reviews)
"It was a decent stay I can’t complain "
United States
Rony
The price is ฿4,288
฿4,908 total
includes taxes & fees
29 Mar - 30 Mar
Doubletree by Hilton Cape Cod - Hyannis
Indoor pool

Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.2 out of 10, Very good, (67 reviews)
"The room was clean had everything in it you could need. The staff was friendly and accommodating ice machine easily accessible and a filtered water cooler in the lobby was great. Pool area was closed but it looked like a nice area."
United States
Marilyn
The price is ฿3,539
฿4,051 total
includes taxes & fees
26 Mar - 27 Mar
Courtyard Resort
Free daily continental breakfast

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1,001 reviews)
"It was clean and comfortable. "
United States
Magdala
The price is ฿3,406
฿3,898 total
includes taxes & fees
31 Mar - 1 Apr
Comfort Inn Hyannis - Cape Cod
Exterior

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,025 reviews)
"Clean room, friendly staff"
United States
Dennis
The price is ฿2,422
฿2,771 total
includes taxes & fees
22 Mar - 23 Mar
Cape Sands Inn
Exterior

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1,002 reviews)
"Clean room, helpful front desk."
United States
Mara
The price is ฿4,057
฿5,954 total
includes taxes & fees
30 Mar - 31 Mar
Hyannis Harbor Hotel
Exterior

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,001 reviews)
"Pool was great!"
United States
Colleen
The price is ฿3,701
฿4,236 total
includes taxes & fees
26 Mar - 27 Mar
Holiday Inn Hyannis by IHG
Front of property

Hyannis Host Inn

Hyannis Host Inn
2.0 star property
1.6 km from Main Street Hyannis
7.8 out of 10, Good, (457 reviews)
"Was a very nice stay! "
United States
Luis
The price is ฿3,214
฿3,679 total
includes taxes & fees
2 Apr - 3 Apr
Hyannis Host Inn
Exterior

Sea Breeze Inn

Sea Breeze Inn
2.5 star property
1.8 km from Main Street Hyannis
7.8 out of 10, Good, (194 reviews)
"Nice place to stay "
United States
Kevin
The price is ฿2,204
฿2,522 total
includes taxes & fees
5 Apr - 6 Apr
Sea Breeze Inn
Lobby

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.0 out of 10, Good, (1,001 reviews)
"Love this place "
United States
M
The price is ฿2,874
฿3,613 total
includes taxes & fees
23 Mar - 24 Mar
Hyannis Plaza Hotel
Lobby

Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area

Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area
2.0 star property
1.5 km from Main Street Hyannis
7.0 out of 10, Good, (1,000 reviews)
"Great hotel, friendly staff!"
United States
Amy
The price is ฿2,403
฿2,750 total
includes taxes & fees
6 Apr - 7 Apr
Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area
Iron/ironing board, free WiFi, bed sheets

Relax Inn Cape Cod

Relax Inn Cape Cod
2.0 star property
1.4 km from Main Street Hyannis
6.4 out of 10, (754 reviews)
"Good staff, good room, good price."
United States
Andrew
The price is ฿2,470
฿2,826 total
includes taxes & fees
3 Apr - 4 Apr
Relax Inn Cape Cod
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Main Street Hyannis

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Restaurant
Hyannis Travel Inn
2.5 star property
9.6
Exceptional
1,000 reviews
View
Interior entrance
Anchor In Distinctive Waterfront Lodging
3.0 star property
9.4
Exceptional
1,000 reviews
View
Dining
Sea Street Inn
4.0 star property
9.8
Exceptional
45 reviews
View
Indoor pool, seasonal outdoor pool
Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
9.2
Wonderful
119 reviews
View
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
8.8
Excellent
1,000 reviews
View

Top Main Street Hyannis Hotel Reviews

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

8/10 Good
"Aceptable "
Australia 2-night trip
Posted 15 hours ago
Margaritaville Resort Cape Cod

Hotels near other Main Street Hyannis attractions

John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts

John F. Kennedy Hyannis Museum

4.4/5 (259 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
See properties
Cape Cod Maritime Museum which includes a bay or harbor and signage

Cape Cod Maritime Museum

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the beautiful beaches in this family-friendly area or visit its seafood restaurants.
See properties

Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 186 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Comfort Inn Hyannis - Cape Cod is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good options within a short distance include Hyannis Travel Inn and Courtyard Resort.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 186 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Whydah Pirate Museum and Cape Cod Maritime Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Veterans Memorial Park and Dennis Pond Conservation Area are peaceful spots to stop and take in some fresh air.