Find hotels in Lithium, MO from ฿2,211

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
23 Dec - 24 Dec
Tomorrow
24 Dec - 25 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Lithium hotels

Exterior
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (542)
Modern accommodation near Perryville Country Club featuring an indoor pool for morning swims and a 24-hour fitness centre. Enjoy complimentary breakfast, WiFi and parking while exploring nearby Saint Marys Lake. Travellers praise the clean rooms and helpful staff.
"Clean room "
United States
Larry
The price is ฿2,733
฿3,128 total
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Express & Suites Perryville by IHG
Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted bathtub
Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
2.5 star property
Chester
8.6 out of 10, Excellent, (351)
Unwind in this tranquil Chester hotel where quiet rooms offer respite after exploring nearby attractions like Popeye Museum. Free perks include continental breakfast, WiFi, and parking, while the 24-hour fitness centre keeps routines on track.
"The room was clean and the staff were friendly. "
United States
RODNEY
The price is ฿2,387
฿2,649 total
includes taxes & fees
26 Dec - 27 Dec
Baymont by Wyndham Chester IL
Exterior
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very good, (941)
This family-friendly Perryville motel features a refreshing indoor pool and 24-hour fitness centre. Enjoy free breakfast, WiFi, and parking while staying minutes from Perryville Country Club and Saint Marys Lake. Guests rave about the clean rooms and attentive staff.
"My girlfriend found hair and leaves in the tub of our room. This is after we checked in and it was only for one night."
United States
Timothy
The price is ฿2,082
฿2,384 total
includes taxes & fees
29 Dec - 30 Dec
Super 8 by Wyndham Perryville
Free self-parking
Triangle Inn Motel

Triangle Inn Motel

Triangle Inn Motel
2.0 star property
Ste Genevieve
8.0 out of 10, Very good, (42)
Situated just a short drive from Ste Genevieve's Museum Learning Centre and Historic District, this welcoming hotel provides convenient amenities including free WiFi, complimentary parking, and 24-hour front desk service.
"The staff was very accommodating."
United States
Herbert
The price is ฿2,381
฿2,657 total
includes taxes & fees
31 Dec - 1 Jan 2026
Triangle Inn Motel
Room, 2 Queen Beds, Non Smoking | Premium bedding, individually furnished, desk, laptop workspace
Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve

Microtel Inn & Suites by Wyndham Sainte Genevieve
2.5 star property
Ste Genevieve
8.8 out of 10, Excellent, (611)
Tranquil accommodation near the Ste Genevieve Museum Learning Centre and Historic District. Enjoy complimentary breakfast, WiFi and parking while business travellers appreciate the helpful staff. Clean rooms provide a serene environment after exploring local attractions.
"Excellent "
United States
James
The price is ฿2,316
฿2,584 total
includes taxes & fees
25 Dec - 26 Dec
Microtel Inn & Suites by Wyndham Sainte Genevieve
Seasonal outdoor pool
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville
2.0 star property
Perryville
6.8 out of 10, (415)
Begin your day with complimentary on-the-go breakfast at this welcoming Perryville hotel. Enjoy a refreshing swim in the seasonal outdoor pool after exploring nearby Perryville Country Club and Saint Marys Lake. Free Wi-Fi and parking enhance your stay.
"Was a nice place."
United States
Lesliee
The price is ฿1,931
฿2,211 total
includes taxes & fees
13 Jan - 14 Jan 2026
Days Inn by Wyndham Perryville
Lobby
Quality Inn Perryville I-55

Quality Inn Perryville I-55

Quality Inn Perryville I-55
2.5 star property
Perryville
6.6 out of 10, (124)
Modern comfort awaits at this Perryville hotel with complimentary breakfast, WiFi, and parking. After a morning swim, explore nearby Saint Marys Lake or practice your swing at the local country club.
"Nice place would recommend Mary Jane’s if you’re looking for good food "
United States
Andrew
The price is ฿2,158
฿2,471 total
includes taxes & fees
29 Dec - 30 Dec
Quality Inn Perryville I-55
55-inch Smart TV with digital channels, TV, streaming services
Urban Lofts

Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.2 out of 10, Wonderful, (17)
Located near Feltz Street Park, this aparthotel offers memory foam beds and sofa beds for a comfortable stay. The convenient kitchens and washing machines/dryers make extended visits easy, while free WiFi and parking add value to your experience.
"Great place to stay! "
United States
Eric
Urban Lofts
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Lithium Hotel Reviews

Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL

10/10 Excellent
"The hotel has been declining in recent years but the new management is working to make things better and they are doing a great job. Our room was very comfortable and clean. The staff were very friendly and helpful. It was an enjoyable experience and we will stay here again. "
angela 2-night trip
Posted 2 weeks ago
Baymont by Wyndham Chester IL
Triangle Inn Motel

Triangle Inn Motel

10/10 Excellent
"Dee was the most gracious owner and manager of the motel. Said to call her if we needed anything and was very helpful overall. Bed was clean and comfortable. Even though the rooms could use an updating, it was clean and served the purpose of a good sleep. "
Mary 1-night trip
Posted 1 month ago
Triangle Inn Motel

More cheap stays in Lithium

Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

1500 Liberty Street Perryville MO
The price is ฿1,931 per night from 13 Jan to 14 Jan
฿1,931
฿2,211 total
13 Jan - 14 Jan 2026
includes taxes & fees
6.8/10 (415 reviews)

Frequently asked questions

What's the best place for a stay in Lithium?
Located 7.5 mi (12 km) from the heart of Lithium, Baymont by Wyndham Chester IL is a top choice for your stay, based on our traveller data. Other good choices for your stay in the area are Holiday Inn Express & Suites Perryville by IHG and Super 8 by Wyndham Perryville. See all available top hotels, or vacation rentals in Lithium.
If I need to cancel my hotel reservation in Lithium, will I receive a refund?
Yes, the majority of hotel reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Lithium.
What is staying in Lithium like?
Those travelling to Lithium will definitely enjoy the sights to see and things to do. There are 67 hotels and other accommodation options in the surrounding area. Find out more about Lithium.
What should I see while I'm in Lithium?
Places to visit in the wider area include Popeye Museum, National Shrine of Our Lady of the Miraculous Medal and Perryville Country Club. You'll also find Fort Kaskaskia and Sainte Genevieve Winery in the area. Take a look at what more there is to see and do in Expedia's Lithium guide.
What's the weather like in Lithium?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Lithium is 1215 mm.

Explore a world of travel with Expedia