Find hotels in La Mesilla, NM from ฿2,081

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26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
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26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for La Mesilla hotels

Suite, 1 King Bed | View from room
Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder
4.0 star property
Santa Fe
8.6 out of 10, Excellent, (1007)
"Room was clean and staff was friendly"
United States
Ursula
The price is ฿3,385
฿3,869 total
includes taxes & fees
20 Jan - 21 Jan 2026
Hilton Santa Fe Buffalo Thunder
Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas
Hotel Glorieta

Hotel Glorieta

Hotel Glorieta
3.5 star property
Santa Fe
8.0 out of 10, Very good, (43)
"Loved the decor"
United States
Marian
The price is ฿2,936
฿4,277 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Glorieta
Property grounds
The Inn at the Delta

The Inn at the Delta

The Inn at the Delta
3.0 star property
Espanola
9.4 out of 10, Exceptional, (1004)
"Lovely place with a lot of New Mexico charm."
United States
Barbara
The Inn at the Delta
Lobby sitting area
Cities Of Gold Casino

Cities Of Gold Casino

Cities Of Gold Casino
3.0 star property
Santa Fe
8.0 out of 10, Very good, (1063)
"Always love staying here everything was good"
United States
Rafael
The price is ฿1,820
฿2,081 total
includes taxes & fees
25 Jan - 26 Jan 2026
Cities Of Gold Casino
Free daily buffet breakfast
Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG
2.5 star property
Los Alamos
8.8 out of 10, Excellent, (746)
"The room was spotless , all the employees are friendly and have great customer service. The breakfast is really good . "
United States
Claudia
The price is ฿3,791
฿4,248 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Los Alamos Entrada Park by IHG
In-room safe, iron/ironing board, free WiFi, bed sheets
Hampton Inn & Suites Los Alamos White Rock

Hampton Inn & Suites Los Alamos White Rock

Hampton Inn & Suites Los Alamos White Rock
2.5 star property
Los Alamos
9.0 out of 10, Wonderful, (677)
"The ground were clean along with the facilities. The manager on duty was very hospitable, would stay again."
United States
Monica
The price is ฿3,185
฿3,569 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hampton Inn & Suites Los Alamos White Rock
Restaurant
Homewood Suites by Hilton Santa Fe-North

Homewood Suites by Hilton Santa Fe-North

Homewood Suites by Hilton Santa Fe-North
3.0 star property
Santa Fe
9.2 out of 10, Wonderful, (1001)
"The staff was very friendly. "
United States
Vanessa
The price is ฿3,537
฿4,043 total
includes taxes & fees
19 Jan - 20 Jan 2026
Homewood Suites by Hilton Santa Fe-North
Bar (on property)
Ohkay Casino Resort Hotel

Ohkay Casino Resort Hotel

Ohkay Casino Resort Hotel
2.5 star property
Ohkay Owingeh
8.0 out of 10, Very good, (789)
"Breakfast was good . Price was reasonable. Only thing was our tv didn't work. And bed were very ununcomfortable "
United States
Nina
Ohkay Casino Resort Hotel
Free daily self-service breakfast
Wingate by Wyndham Los Alamos

Wingate by Wyndham Los Alamos

Wingate by Wyndham Los Alamos
2.5 star property
Los Alamos
8.0 out of 10, Very good, (573)
"Solid hotel with very friendly and supportive staff. "
United States
Markus
The price is ฿2,489
฿2,789 total
includes taxes & fees
4 Jan - 5 Jan 2026
Wingate by Wyndham Los Alamos
Exterior
Casa Escondida Bed & Breakfast

Casa Escondida Bed & Breakfast

Casa Escondida Bed & Breakfast
3.0 star property
Chimayo
9.4 out of 10, Exceptional, (262)
"Beautiful historic property. Great staff and excellent breakfast. "
United States
Julie
The price is ฿3,687
฿4,116 total
includes taxes & fees
7 Jan - 8 Jan 2026
Casa Escondida Bed & Breakfast
Terrace/patio
Four Seasons Resort Rancho Encantado Santa Fe

Four Seasons Resort Rancho Encantado Santa Fe

Four Seasons Resort Rancho Encantado Santa Fe
5.0 star property
Santa Fe
9.4 out of 10, Exceptional, (265)
"Food options were good, but limited. The scenery was breathtaking as well as the nearby Santa Fe and the tours we took to the Indian reservation and Los Alamos"
United States
ILAN
The price is ฿15,828
฿19,698 total
includes taxes & fees
25 Jan - 26 Jan 2026
Four Seasons Resort Rancho Encantado Santa Fe
Free continental breakfast
Rodeway Inn Española

Rodeway Inn Española

Rodeway Inn Española
2.0 star property
Espanola
6.2 out of 10, (466)
"Friendly staff, clean on the surface, appears to be in renovation stage, heat and air worked fine, lighted/fenced parking, filthy sheets, cigarette burned bed covers, no (soap, shampoo, conditioner, hair dryer), and breakfast was just coffee and oatmeal packets. This place is perfect as a homeless refuge or a 1 hour rental. Do yourself a favor and stay at one of the local casinos."
United States
M L
The price is ฿2,084
฿2,369 total
includes taxes & fees
27 Jan - 28 Jan 2026
Rodeway Inn Española
Exterior
Bishop's Lodge, Auberge Collection

Bishop's Lodge, Auberge Collection

Bishop's Lodge, Auberge Collection
5.0 star property
Tesuque
9.4 out of 10, Exceptional, (93)
"Great location, Resort, amenities, excellent service and great restaurant chef!!!!!"
United States
James R
Bishop's Lodge, Auberge Collection
Spa
Motel 6 Espanola, NM

Motel 6 Espanola, NM

Motel 6 Espanola, NM
2.0 star property
Espanola
6.4 out of 10, (517)
"One of the cleanest motels I’ve been in a long time. The water was hot. It was good and they provided coffee. I will definitely stay here again."
United States
Sally
The price is ฿3,072
฿3,493 total
includes taxes & fees
1 Jan - 2 Jan 2026
Motel 6 Espanola, NM
View from room
Days Inn by Wyndham Espanola

Days Inn by Wyndham Espanola

Days Inn by Wyndham Espanola
2.0 star property
Espanola
5.8 out of 10, (587)
"Good place to stay"
United States
Sergio
The price is ฿3,014
฿3,427 total
includes taxes & fees
18 Jan - 19 Jan 2026
Days Inn by Wyndham Espanola
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesilla Hotel Reviews

Cities Of Gold Casino

Cities Of Gold Casino

10/10 Excellent
"We stay at Cities Of Gold often - it’s a convenient/affordable place close to my job when I have to schedule offsite. It’s been a Blessing for us because of the price!!"
Rachel 1-night trip
Posted 2 weeks ago
Cities Of Gold Casino

More cheap stays in La Mesilla

Wingate by Wyndham Los Alamos

Wingate by Wyndham Los Alamos

2455 Trinity Dr Los Alamos NM
The price is ฿2,489 per night from 4 Jan to 5 Jan
฿2,489
฿2,789 total
4 Jan - 5 Jan 2026
includes taxes & fees
8/10 Very Good! (572 reviews)

Frequently asked questions

What's the best place for a stay in La Mesilla?
Located 7.4 mi (11.9 km) from the heart of La Mesilla, Hilton Santa Fe Buffalo Thunder is a top choice for your stay, based on our traveller data. Other good choices for your visit to the area are Cities Of Gold Casino and Hotel Glorieta. See all available top hotels, or vacation rentals in La Mesilla.
If I need to cancel my hotel reservation in La Mesilla, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesilla.
What is staying in La Mesilla like?
Visitors will definitely enjoy all that La Mesilla has to offer. There are 371 hotels and other accommodation options in the surrounding area. Find out more about La Mesilla.
What should I see while I'm in La Mesilla?
Places to visit in the wider area include Cities of Gold Casino, Towa Golf Resort and Buffalo Thunder Resort and Casino. You'll also find Santuario de Chimayo and Lowlows Lowrider Art Place in the area. Take a look at what more there is to see and do in Expedia's La Mesilla guide.
What's the weather like in La Mesilla?
The hottest months are usually July and June, with an average temperature of 21°C, while the coldest months are January and December, with an average of 0°C. The snowiest months in La Mesilla are March, January, December and February, with each month seeing an average of 22 cm of snowfall.