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Our top choices for East Main Street hotels

1. Dtwn Walkability! Grand Junction Couple's Retreat

Dtwn Walkability! Grand Junction Couple's Retreat
3.0 star property
East Main Street
10.0 out of 10, Exceptional, (3 reviews)
"Our stay was fantastic! The location was perfect—close to everything. The property was clean and loved the decor. The host was super responsive and helpful, making our trip stress-free. Highly recommend!"
United States
renee
The price is ฿3,791
฿8,739 total
includes taxes & fees
23 Jun - 24 Jun
Dtwn Walkability! Grand Junction Couple's Retreat

2. La Quinta Inn & Suites by Wyndham Fruita

La Quinta Inn & Suites by Wyndham Fruita
3.0 star property
18.8 km from East Main Street
8.4 out of 10, Very good, (1,013 reviews)
"Clean, quiet, comfortable beds, breakfast was great, parking was good"
United States
Leo
The price is ฿3,827
฿4,373 total
includes taxes & fees
22 Jun - 23 Jun
La Quinta Inn & Suites by Wyndham Fruita

3. Super 8 by Wyndham Fruita

Super 8 by Wyndham Fruita
2.0 star property
18.6 km from East Main Street
8.2 out of 10, Very good, (1,003 reviews)
The price is ฿2,225
฿2,543 total
includes taxes & fees
28 Jun - 29 Jun
Super 8 by Wyndham Fruita

4. Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites
2.5 star property
8.7 km from East Main Street
8.8 out of 10, Excellent, (877 reviews)
"Convenient, clean, comfortable place at a good price!"
United States
John
The price is ฿3,929
฿4,176 total
includes taxes & fees
28 Jun - 29 Jun
Best Western Grande River Inn & Suites

5. Wine Country Inn Palisade

Wine Country Inn Palisade
3.5 star property
17.1 km from East Main Street
9.6 out of 10, Exceptional, (1,006 reviews)
"The Breakfast was awesome and the view of vineyard was beautiful."
United States
Joseph
The price is ฿5,607
฿6,213 total
includes taxes & fees
22 Jun - 23 Jun
Wine Country Inn Palisade

6. Spoke and Vine Motel

Spoke and Vine Motel
2.5 star property
17.4 km from East Main Street
9.8 out of 10, Exceptional, (173 reviews)
"Cute little Hotel. Friendly people in the small community of Palisade. the day we were there they had live music, a food truck and a small bar. It wasfun"
United States
LeAnn
The price is ฿5,607
฿6,213 total
includes taxes & fees
6 Jul - 7 Jul
Spoke and Vine Motel

7. Camp Eddy

Camp Eddy
1.0 star property
Pear Park, 1.5 km from East Main Street
9.4 out of 10, Exceptional, (354 reviews)
"Very clean campground but Airstream was older than pics online. Overall we really enjoyed the location and our stay"
United States
John
The price is ฿2,284
฿4,396 total
includes taxes & fees
5 Jul - 6 Jul
Camp Eddy

8. Balanced Rock Inn

Balanced Rock Inn
3.0 star property
19 km from East Main Street
9.0 out of 10, Wonderful, (74 reviews)
"Everything was great. I would stay there again."
United States
William Carey
The price is ฿4,753
฿5,431 total
includes taxes & fees
1 Jul - 2 Jul
Balanced Rock Inn

9. Grand Vista Hotel

Grand Vista Hotel
3.5 star property
Horizon Drive District, 5.5 km from East Main Street
8.2 out of 10, Very good, (3,788 reviews)
"Great location"
United States
Virginia
The price is ฿2,643
฿3,031 total
includes taxes & fees
22 Jun - 23 Jun
Grand Vista Hotel

10. Castle Creek B&B

Castle Creek B&B
3.5 star property
3.4 km from East Main Street
9.8 out of 10, Exceptional, (222 reviews)
"Wow! Close to Grand Junction airport - so we stayed our first and last days of a 7 day national park quest. Beautifully decorated rooms. Great breakfasts. Easy to find and park!"
United States
Valerie
The price is ฿4,510
฿5,171 total
includes taxes & fees
23 Jun - 24 Jun
Castle Creek B&B

11. Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction
2.5 star property
Horizon Drive District, 5.3 km from East Main Street
8.2 out of 10, Very good, (1,949 reviews)
"Great staff, breakfast, and comfortable bed and clean room"
United States
Linda
The price is ฿2,664
฿3,054 total
includes taxes & fees
5 Jul - 6 Jul
Ramada by Wyndham Grand Junction

12. Quality Inn Grand Junction near University

Quality Inn Grand Junction near University
3.0 star property
Horizon Drive District, 4.9 km from East Main Street
8.8 out of 10, Excellent, (1,005 reviews)
"great stay"
United States
brooke
The price is ฿2,878
฿3,300 total
includes taxes & fees
28 Jun - 29 Jun
Quality Inn Grand Junction near University

13. The Homestead

The Homestead
4.5 star property
20.4 km from East Main Street
10.0 out of 10, Exceptional, (74 reviews)
"Cute place, nicely updated. Gorgeous view of area mesas. Nice yard with games and gorgeous fire pit area."
United States
Mohsen and Barbara
The price is ฿7,081
฿7,454 total
includes taxes & fees
22 Jun - 23 Jun
The Homestead

14. The Hotel Melrose

The Hotel Melrose
2.0 star property
Historic Grand Junction, 1.3 km from East Main Street
9.2 out of 10, Wonderful, (161 reviews)
"Perfect location and sweet bar area. Super comfortable room! "
United States
Michelle
The price is ฿6,017
฿6,899 total
includes taxes & fees
28 Jun - 29 Jun
The Hotel Melrose

15. Red Roof Inn Grand Junction

Red Roof Inn Grand Junction
2.0 star property
9.2 km from East Main Street
6.8 out of 10, (1,001 reviews)
"The room was very clean and the front desk personnel did a great job."
United States
Stephanie
The price is ฿2,373
฿2,721 total
includes taxes & fees
2 Jul - 3 Jul
Red Roof Inn Grand Junction

16. Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown
2.5 star property
Historic Grand Junction, 1.4 km from East Main Street
9.2 out of 10, Wonderful, (1,001 reviews)
"Very comfortable stay"
United States
Gail
The price is ฿4,519
฿5,181 total
includes taxes & fees
28 Jun - 29 Jun
Tru by Hilton Grand Junction Downtown

17. Econo Lodge Grand Junction North

Econo Lodge Grand Junction North
2.0 star property
Horizon Drive District, 5.2 km from East Main Street
8.2 out of 10, Very good, (1,001 reviews)
"The staff was great and very helpful along with really clean rooms and a wonderful breakfast 😀"
United States
Theresa
The price is ฿2,770
฿3,176 total
includes taxes & fees
28 Jun - 29 Jun
Econo Lodge Grand Junction North

18. Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado
2.0 star property
Horizon Drive District, 4.8 km from East Main Street
7.4 out of 10, Good, (1,007 reviews)
"Pleasant staff, clean room, comfy bed. Would stay there again."
United States
Glenn
The price is ฿2,403
฿2,755 total
includes taxes & fees
28 Jun - 29 Jun
Super 8 by Wyndham Grand Junction Colorado

19. Comfort Inn & Suites Fruita - Grand Junction

Comfort Inn & Suites Fruita - Grand Junction
2.5 star property
18.5 km from East Main Street
8.4 out of 10, Very good, (1,001 reviews)
"Stayed one night. Good food options within walking distance."
United States
John
The price is ฿3,075
฿3,514 total
includes taxes & fees
12 Jul - 13 Jul
Comfort Inn & Suites Fruita - Grand Junction

20. La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction
3.0 star property
Horizon Drive District, 5.4 km from East Main Street
8.8 out of 10, Excellent, (2,854 reviews)
"Excellent stay. Rooms clean, friendly staff, excellent breakfast options."
United States
Lynda
The price is ฿3,857
฿4,422 total
includes taxes & fees
28 Jun - 29 Jun
La Quinta Inn & Suites by Wyndham Grand Junction
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in East Main Street

Find the best East Main Street areas for the activities you enjoy most.

Redlands

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

Downtown

Though Downtown may not have many top sights, you can venture to the surrounding area to see attractions like Western Colorado Botanical Gardens and Bananas Fun Park.

Pear Park

While visiting Pear Park, you might make a stop by sights like Colorado River and James M. Robb – Colorado River State Park.

Historic Grand Junction

Visitors highly recommend Historic Grand Junction for its abundant dining options, and you can make a stop by Museum of the West while you're in town.

Horizon Drive District

Horizon Drive District might not have many top sights, but Grand Junction Motor Speedway and Canyon View Park are two attractions nearby that you can check out.

Top East Main Street Hotel Reviews

Frequently asked questions

What's it like in East Main Street?
Travellers will be sure to enjoy their time in Grand Junction's East Main Street neighbourhood.
How many hotels can I expect to find in the East Main Street area?
If you're searching for places to stay in Grand Junction, Expedia has something to meet your needs with 24 East Main Street hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in East Main Street, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to get the best deals in East Main Street.
What is there to do around this Grand Junction neighbourhood?
A few places to visit in the area around East Main Street include Museum of the West, Western Colorado Botanical Gardens and Elliott Tennis Center. While you're out sightseeing, Western Colorado Center for the Arts and Tennis Junction Indoor Center are a couple of additional sights to visit in Grand Junction.