The Best Hotels Closest to Don and Sybil Harrington Cancer Center in Amarillo - 2026 Updated Prices

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Our top choices for Don and Sybil Harrington Cancer Center hotels

A spacious lobby with a modern design, featuring a seating area with colorful cushions, a large chandelier, and a flat-screen TV mounted on the wall.

A modern kitchen with wooden cabinets, a white countertop, and blue glass panels on the walls.

A vending area with snack and drink options, including a refrigerated section with beverages and a shelf stocked with various snacks.

1. Best Western Plus Medical Center

0.4 km from Don and Sybil Harrington Cancer Center

Elizabeth

฿3,080

฿3,541 total

includes taxes & fees

27 Sept - 28 Sept

A spacious restaurant with high ceilings, stone walls, and large windows.

A living room with a stone fireplace, a sofa set, and a patterned rug.

A multi-story hotel with a prominent entrance, multiple balconies, and a clear blue sky.

An indoor swimming pool with clear poolside areas, safety signs, and seating arrangements.

2. Drury Inn & Suites Amarillo

1.9 km from Don and Sybil Harrington Cancer Center

Randall

฿3,589

฿4,128 total

includes taxes & fees

27 Sept - 28 Sept

A modern room with a sofa, a chair, a lamp, and a television.

A hotel room with a bed, a sofa, a desk with a chair, a TV, and a framed picture on the wall.

A modern hotel dining area with multiple tables and chairs, a large TV screen, and a central pillar with a geometric design.

A modern lobby with seating areas, a reception desk, and a decorative tree centerpiece.

3. Holiday Inn Express & Suites Amarillo West by IHG

1.4 km from Don and Sybil Harrington Cancer Center

Jeannie

฿3,357

฿3,861 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio with a fire feature, seating, and a grill area.

A modern hotel with a clear entrance, a covered waiting area, and a sign indicating a 15' clearance.

An indoor swimming pool with clear blue walls and large windows, surrounded by seating areas and a view of the outside.

A hotel hallway with a patterned carpet, white doors, and recessed lighting.

4. Hampton Inn & Suites Amarillo West

1.7 km from Don and Sybil Harrington Cancer Center

Miguel

฿3,434

฿3,949 total

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a modern design, featuring a prominent entrance and a parking lot.

A rooftop patio with outdoor seating, stone walls, and large windows.

A hotel room with two beds, a desk, a TV, and a bathroom door.

A modern hotel lobby with a dining area, a reception desk, and a seating area with a coffee table.

5. Hyatt Place Amarillo-West

2.2 km from Don and Sybil Harrington Cancer Center

Vanessa

฿3,552

฿4,156 total

includes taxes & fees

4 Oct - 5 Oct

A modern lounge area with seating, tables, and a kitchen area.

A modern food service area with a central counter, a refrigerated display, and various food items.

A gym with treadmills, exercise balls, and weightlifting equipment.

A pool table in a room with a mural, seating, and a large window.

6. Tru By Hilton Amarillo West

2.1 km from Don and Sybil Harrington Cancer Center

Cory

฿2,775

฿3,213 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with a fire pit, lounge chairs, and a building with large windows and a covered patio.

A swimming pool with clear blue water, a diving board, and a seating area with chairs and tables.

A modern hotel lobby with a central seating area, a dining table, and a TV screen.

A modern hotel room with a kitchenette, a bed, a desk, and a large window.

7. TownePlace Suites by Marriott Amarillo West/Medical Center

1.2 km from Don and Sybil Harrington Cancer Center

angela

฿5,631

฿6,476 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor seating area with stone flooring, cushioned benches, and green chairs.

A modern hotel lobby with a seating area, a bar, and a dining space.

A modern bar area with seating, a bar counter, and a television mounted on the ceiling.

A hotel room with a bed, desk, and seating area.

8. Springhill Suites by Marriott Amarillo

1.6 km from Don and Sybil Harrington Cancer Center

Michael

฿4,066

฿4,676 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with two beds, a TV, a window with blinds, a framed picture on the wall, and a bedside lamp.

A modern kitchen with a black microwave, coffee maker, and a refrigerator.

9. My Place Hotel - Amarillo West/ Medical Center, TX

1.6 km from Don and Sybil Harrington Cancer Center

justin

฿3,201

฿3,681 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with a stone fireplace, a grill, and a dining area with chairs and tables.

A spacious lobby with a fireplace, seating area, and a bar.

A hotel with a modern design, featuring a covered entrance, outdoor seating, and a well-maintained landscape.

A hotel lobby with a reception desk, seating area, and a large window with a view.

10. Homewood Suites by Hilton Amarillo

2.2 km from Don and Sybil Harrington Cancer Center

todd

฿2,966

฿3,411 total

includes taxes & fees

4 Oct - 5 Oct

A swimming pool with clear water, a brick deck, and a waterfall feature.

A hotel room with two beds, a desk with a computer, a chair, and a window with curtains.

A hotel room with a desk, office chair, striped armchair, red sofa, ottoman, and a television.

A traditional living room with leather sofas, a fireplace, and a clock on the wall.

11. Country Inn & Suites by Radisson, Amarillo I-40 West, TX

2 km from Don and Sybil Harrington Cancer Center

Gary

฿2,702

฿3,107 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor seating area with wicker chairs and a fire pit.

A sign instructing to clean up after dogs and dispose of waste, with a trash can nearby.

A multi-story hotel with a prominent 'Home2' sign, a covered entrance, and a parking lot.

A hotel room with a bed, a sofa, a desk, and a television.

12. Home2 Suites by Hilton Amarillo

1.3 km from Don and Sybil Harrington Cancer Center

Amanda

฿3,983

฿4,580 total

includes taxes & fees

18 Oct - 19 Oct

A lobby with a reception desk, seating area, and a stone wall with framed pictures.

A living room with a sofa, armchair, ottoman, coffee table, TV, and artwork on the walls.

A hotel lobby with a reception desk, a sofa, a dining area, and a kitchen.

13. Comfort Inn & Suites Amarillo West Near Medical Center

2.2 km from Don and Sybil Harrington Cancer Center

Alvin

฿2,962

฿3,406 total

includes taxes & fees

28 Sept - 29 Sept

A hotel lobby with a blue sofa, a fireplace, a dining area, and a TV mounted on the wall.

A Fairfield Inn & Suites Marriott hotel with a modern design, featuring a large parking lot and well-maintained landscaping.

A modern living room with a fireplace, a blue sectional sofa, and a flat-screen TV mounted on the wall.

An indoor swimming pool with tiled flooring, yellow lounge chairs, and a ceiling with recessed lighting.

14. Fairfield Inn & Suites Amarillo West/Medical Center

1 km from Don and Sybil Harrington Cancer Center

Tania

฿3,419

฿4,010 total

includes taxes & fees

5 Oct - 6 Oct

A modern living room with a blue sofa, wooden flooring, and framed pictures on the walls.

A modern hotel with multiple floors, a parking lot, and a well-lit entrance.

A hotel room with a bed, a desk with a computer, a chair, a sofa, and a large mirror.

An outdoor patio area with stone walls, seating, and string lights.

15. Everhome Suites Amarillo West - Medical Center

1.2 km from Don and Sybil Harrington Cancer Center

Mohammad

฿3,221

฿3,704 total

includes taxes & fees

15 Oct - 16 Oct

A hotel lobby with a high ceiling, a fireplace, a flat-screen TV, and a large abstract painting on the wall.

A modern living room with a fireplace, orange sofas, and a flat-screen TV.

A hotel room with a dining area, a fireplace, a TV, and a bed.

A hotel room with a large bed, two bedside lamps, a wooden headboard, a nightstand, and a vase with flowers.

16. Yellow City Studios

1 km from Don and Sybil Harrington Cancer Center

Ayvan

฿1,915

฿2,202 total

includes taxes & fees

7 Oct - 8 Oct

A spacious living area with a large sofa, a fireplace, and a patterned floor.

An indoor swimming pool with a tiled floor, ceiling fans, and a seating area with tables and chairs.

A spacious kitchen with a large island, wooden cabinetry, and a minibar area.

A hotel with a large parking lot, a covered entrance, and a prominent American flag.

17. Hilton Garden Inn Amarillo

2.4 km from Don and Sybil Harrington Cancer Center

Gregory

฿2,797

฿3,217 total

includes taxes & fees

10 Oct - 11 Oct

An outdoor seating area with a fire feature, surrounded by modern buildings.

A Courtyard by Marriott hotel with a covered entrance, parking lot, and a clear sky.

A modern living room with a stone wall, a fireplace, and a large sectional sofa.

A modern kitchen with a bar area, a round dining table, and a sofa.

18. Courtyard by Marriott Amarillo West/Medical Center

1.4 km from Don and Sybil Harrington Cancer Center

Ronnie

฿3,915

฿4,526 total

includes taxes & fees

6 Oct - 7 Oct

A spacious indoor area with wooden flooring, multiple seating arrangements including sofas and tables, and large windows allowing natural light.

A hotel room with two beds, a headboard, wall art, a lamp, and a window with curtains.

A reception desk with a wooden finish, a modern abstract painting, and a decorative lamp.

A modern interior with a green carpet, wooden flooring, and a wall with a geometric design.

19. Spark by Hilton Amarillo Medical Center

1.1 km from Don and Sybil Harrington Cancer Center

MICHAEL

฿2,430

฿2,795 total

includes taxes & fees

4 Oct - 5 Oct

A hotel entrance with a glass door, stone pillars, and a clear view of the parking lot.

A hotel room with two beds, a desk with a television, and a chair.

A hotel reception area with a reception desk, a large mirror, and a patterned floor.

A buffet setup with multiple serving stations, including a toaster and a grill, against a tiled backsplash.

20. Sleep Inn & Suites West Medical Center

1.1 km from Don and Sybil Harrington Cancer Center

Lina

฿2,563

฿2,947 total

includes taxes & fees

18 Oct - 19 Oct

View all properties

Compare popular hotels close to Don and Sybil Harrington Cancer Center

Property	Property class	Guest rating
Best Western Plus Medical Center	9.4 Exceptional 1,912 reviews	View
Drury Inn & Suites Amarillo	9.4 Exceptional 2,477 reviews	View
Holiday Inn Express & Suites Amarillo West by IHG	9.4 Exceptional 2,305 reviews	View
Hampton Inn & Suites Amarillo West	9.4 Exceptional 515 reviews	View
Hyatt Place Amarillo-West	9.2 Wonderful 1,345 reviews	View

Top Don and Sybil Harrington Cancer Center Hotel Reviews

Drury Inn & Suites Amarillo

10/10 Excellent

"It was great"

Holiday Inn Express & Suites Amarillo West by IHG

8/10 Good

"The property is easy to find. Road construction makes it a bit challenging to get in to but not impossible."

The Cactus Cove Inn and Suites

10/10 Excellent

"Friendly staff and great breakfast"

Atrea Inn Amarillo

10/10 Excellent

"Really liked the easy check in process, cleanliness of the room, location, the breakfast and courtyard. Would definitely recommend and would stay here again."

Comfort Inn & Suites Amarillo West Near Medical Center

8/10 Good

"-"

Spark by Hilton Amarillo Western Plaza

8/10 Good

"Just what we wanted....clean, inexpensive, and comfortable."

Fifth Season Suites

8/10 Good

"A nice place. As I was checking in I asked about the pool and was told that it was open but there was a chain & lock on it. Later, I saw some people in the pool and wonder if it was employees. I asked if there was a handicap room or at least first floor. We were assigned a room on first floor but as far from the front as could be. After lugging our things way down there, I found out that we could have parked in the back close to a door near our room. I wish the woman checking me in would have mentioned that, especially since I'd mentioned handicap. And she watched me walk by with everything. It was shift change time and the person taking her place was very helpful. If it wasn't for this woman, I would have given it 5 stars all around."

Days Inn by Wyndham Amarillo - Medical Center

10/10 Excellent

"Got in very late. Bed was tough which I was happy for. Usually bed is overused at a hotel. I appreciated it being hard. Toilets seats didn't stay in on their own in any place i used the bathroom. Didn't like that."

Red Roof Inn Amarillo West

10/10 Excellent

"I drive from CO to TX regularly and have stayed at a lot of road-side hotels on the route. I usually travel with dogs and bikes, which require a large, pet friendly room. This was the largest and nicest room, in the value space, with a reasonable pet-fee, that I've stayed at in several years, and will become my spot to-stop on the route moving forward. The only thing that could use improvement, was the coffee/breakfast situation - but again, what was there was serviceable. We look forward to staying there again in the future!"

Frequently asked questions

What's the area like around Don and Sybil Harrington Cancer Center?

Don and Sybil Harrington Cancer Center is located in a family-friendly area of Amarillo known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 44 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Don and Sybil Harrington Cancer Center?

Holiday Inn Express & Suites Amarillo West by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.9 mi (1.4 km) from Don and Sybil Harrington Cancer Center. Other good options within a short distance include Spark by Hilton Amarillo Medical Center and Red Roof Inn Amarillo West.

How many hotels should I expect to find near Don and Sybil Harrington Cancer Center?

Expedia has 44 hotels and other accommodation options within a mile from Don and Sybil Harrington Cancer Center.

If I need to cancel the hotel reservation for my stay near Don and Sybil Harrington Cancer Center, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get the best deals near Don and Sybil Harrington Cancer Center.

What can I see and do near Don and Sybil Harrington Cancer Center?

Don Harrington Discovery Center, Amarillo Museum of Art and Amarillo Art Center feature captivating exhibits. Learn about local history at Historic 6th Street Sign and Harrington House. You can enjoy live performances at Amarillo Little Theatre and Globe-News Center.

Search Hotels Near Don and Sybil Harrington Cancer Center, Amarillo

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Our top choices for Don and Sybil Harrington Cancer Center hotels

1. Best Western Plus Medical Center

2. Drury Inn & Suites Amarillo

3. Holiday Inn Express & Suites Amarillo West by IHG

4. Hampton Inn & Suites Amarillo West

5. Hyatt Place Amarillo-West

6. Tru By Hilton Amarillo West

7. TownePlace Suites by Marriott Amarillo West/Medical Center

8. Springhill Suites by Marriott Amarillo

9. My Place Hotel - Amarillo West/ Medical Center, TX

10. Homewood Suites by Hilton Amarillo

11. Country Inn & Suites by Radisson, Amarillo I-40 West, TX

12. Home2 Suites by Hilton Amarillo

13. Comfort Inn & Suites Amarillo West Near Medical Center

14. Fairfield Inn & Suites Amarillo West/Medical Center

15. Everhome Suites Amarillo West - Medical Center

16. Yellow City Studios

17. Hilton Garden Inn Amarillo

18. Courtyard by Marriott Amarillo West/Medical Center

19. Spark by Hilton Amarillo Medical Center

20. Sleep Inn & Suites West Medical Center

Compare popular hotels close to Don and Sybil Harrington Cancer Center

Top Don and Sybil Harrington Cancer Center Hotel Reviews

Drury Inn & Suites Amarillo

Holiday Inn Express & Suites Amarillo West by IHG

The Cactus Cove Inn and Suites

Atrea Inn Amarillo

Comfort Inn & Suites Amarillo West Near Medical Center

Spark by Hilton Amarillo Western Plaza

Fifth Season Suites

Days Inn by Wyndham Amarillo - Medical Center

Red Roof Inn Amarillo West

Frequently asked questions