Search Boutique Hotels in Cincinnati

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Check availability on Cincinnati Boutique Hotels

Tonight
30 Dec - 31 Dec
Tomorrow
31 Dec - 1 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Our top choices for Cincinnati boutique hotels

Egyptian cotton sheets, premium bedding, in-room safe, laptop workspace
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati
4.5 star property
Downtown Cincinnati
8.6 out of 10, Excellent, (1007)
"Pleasant stay"
United States
Tim
The price is ฿4,720
฿5,787 total
includes taxes & fees
6 Jan - 7 Jan 2026
21c Museum Hotel Cincinnati
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cincinnati Hotel Reviews

21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

10/10 Excellent
"Breakfast was great; but was not included in the price of the room."
Susan 1-night trip
Posted 5 days ago
21c Museum Hotel Cincinnati

Frequently asked questions

What's the best boutique-style hotel in Cincinnati?
21c Museum Hotel Cincinnati is a favourite hotel with Expedia travellers looking for a stylish stay, and features a full-service spa and massages.
What's there to see and do in Cincinnati?
Visitors speak positively about this destination's art galleries, great live music and beautiful island views. Fountain Square, Aronoff Center for the Arts and Taft Theatre are some of the local sights worth visiting. Some other things you might want to enjoy include National Underground Railroad Freedom Center, Cincinnati Reds Hall of Fame and Museum and The Andrew J Brady Music Center.
What kind of weather should I plan for when I travel to Cincinnati?
Understanding the weather in Cincinnati will help you enjoy your stay to the fullest. The hottest months are usually July and August, with an average temperature of 23°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Cincinnati is 1280 mm.
What's the best way to get to my boutique hotel in Cincinnati?
You have a few options for travelling to and around Cincinnati. The closest major airport is Cincinnati, OH (LUK-Cincinnati Municipal - Lunken Field), which is located 4.4 mi (7.1 km) away, but Cincinnati-Northern Kentucky Int'l Airport (CVG) may also be an option. You can walk to nearby metro stations including Fountain Square Tram Stop, 247 Telemarketing Tram Stop and Richter & Phillips Tram Stop.