Day 1: From Cusco to Paradise Lodge. Visit Nincamarca's pre-Incan towers & Paucartambo. Enjoy views from Tres Cruces and explore Manu National Park's flora and fauna.
Day 2: From Paradise Lodge to Hummingbird Lodge. Drive to Atalaya port, visit a local farm and a coca plantation. Boat ride on Madre de Dios river observing wildlife. Evening night safari.
Day 3: From Hummingbird Lodge to Casa Matsiguenka Lodge. Sail on Manu river spotting wildlife. Explore Amazon rainforest trails and visit Cocha Otorongo lake. Optional night jungle tour.
Day 4: Explore Lake Cocha Salvador by canoe, spot wildlife including giant river otters. Hike trails to see monkeys and medicinal plants. Return to Casa Matsiguenka for the night.
Day 5: Early boat ride to Cocha Brascho Lagoon. Look out for anacondas and other snakes. Evening at El Dorado Lodge.
Day 6: From El Dorado Lodge to Palotoa Eco Lodge. Sail on Madre de Dios river, hike to a viewpoint for sunset views of parrots and macaws. Evening nocturnal tour in the reserve.
Day 7: Return from Palotoa to Cusco. Breakfast at the lodge, boat to Atalaya port, and drive back to Cusco, arriving around 07:30 PM.